solu on | Updated RATED A+ 2026| NEW
What 3 types of pa ent characteris cs may alter the volume of distribu on?
* Age
* Edema
* Gender
What is the term for a drug that displays a degree of affinity for a receptor that s mulates a
response?
Agonist
Which route of administra on guarantees 100% bioavailability?
IV
The healthcare provider is going to prescribe a medica on for topical administra on. To prevent
water absorp on or evapora on, which formula should be used?
Ointment
What type of drug results in a higher volume of distribu on b/c of the low-fat content content
in the bloodstream?
Lipid-soluble drugs
Which factor affec ng oral absorp on of a drug is decreased in pregnant compared to non
pregnant women?
GI mo lity
At which point a-er concep on does a developing fetus become suscep ble to the effects of
drugs?
Day 14
What is the most common method for pediatric dosing?
Body weight-based dosing. mg/kg
What is the. best method for reducing the likelihood of a medica on error in a pediatric
pa ent?
,Verifying pa ent weight
A medica on with what characteris c is preferred for use during breas2eeding to reduce the
risk of harm to the infant?
Short half-life
What accounts for the increased risk of orthosta c hypotension in older adults?
* Changes in cerebral blood flow
* Loss of the baroreceptor reflex
A 73-year-old woman is admi8ed to the hospital for pos-op management following a fall and hip
fx. The pa ent typically drinks 3 to 4 alcoholic drinks per day. What 1st line symptom-directed
therapy for mild symptoms of alcohol withdrawal is most appropriate?
Lorazepam
Which pa ent with demen a is an appropriate candidate for considera on of an psycho c
medica on?
A. Pa ent who is agitated and threatening self-harm
B. Pa ent experiencing new onset insomnia
C. Pa ent with uncontrolled pain
D. Pa ent experiencing new-onset anxiety
A. pa ent who is agitated and threatening self-harm
What is an appropriate HgA1c goal for an OA with moderate comorbidity and a life expectancy
of less than 10 years?
A. < 6.5%
B. 6.5-7%
C. 7.5-8%
D. 8.5-9 %
C. 7.5-8%
,What term refers to the study of inherited single or a few gene varia ons on drug therapy and
response?
Pharmacogene cs
On average, what percentage of the human genome is iden cal b/w two unrelated individuals?
99.9%
When interviewing the parent of a 7yo with CF, the health care provider discovers that the
child's aunt has a hx of hearing loss. The provider counsels the child's parent that the child may
benefit from gene c screening prior to therapy with what class of drugs?
Aminoglycosides
A 66 yo pa ent who is prescribed warfarin for afib has a persistently supra therapeu c INR
despite mul ple dosage adjustments and excellent medica on adherence. The pa ent is taking
no other medica ons. Gene c tes ng of the pa ent's CYP2C9 may reveal that the pa ent's
enzyme ac vity is ...
decreased
A pa ent who recently had a stent placed following a MI undergoes gene c tes ng. As a result,
the provider decides that the pa ent should not be given clopidogrel. Which result appears on
the pa ent's test?
A. CYP2C19 (1/1)
B. CYP2C19 (2/2)
C. CYP2C9 (1/1)
D. CYP2C9 (2/2)
B. CYP2C19 (2/2)
What is the first step in the prescribing process?
Determine an accurate diagnosis
In which phase of clinical trials is the most effec ve routes of administra on and dosage ranges
for a drug determined?
Phase I
, What is the best method for disposing of an unused drug?
Take it to a community drug take-back program
Which type of controlled substances require a new prescrip on to be wri8en prior to each
dispense?
Schedule II drugs
Any noxious, unintended, and undesired effect that occurs at normal drug doses
Adverse drug reac on
A 73 yo pa ent has been recently prescribed a PRN medica on for arthri c pain management.
The pa ents reports at a follow-up appointment that "the medica on has not helped much."
What ques on should the health care provider managing the pa ent's care ask the pa ent
ini ally to assess the cause of the pa ent's report?
A. "How o-en are you taking the drug?"
B. " Are you aware of any drug allergies?"
C. " Since star ng the PRN, are you taking any new drugs on a regular basis?"
D. " Are you consistently taking the food with or without food?"
C. "Since star ng the PRN, are you taking any new drugs on a regular basis?"
A pregnant pa ent recently diagnosed with HIV was recently prescribed oral zidovudine to help
minimize the risk of transferring the infec on to the fetus. The pa ent reports experiencing
diarrhea since star ng the therapy. What interven on will the health care provider managing
the pa ent's care ini ally prescribe?
A. Prescribing an an diarrheal drug
B. Taking the drug as prescribed with a small amount of food
C. d/c the zidovudine and replacing it with another drug
D. Changing the route of administra on of the zidovudine to IV
B. taking the drug as prescribed with a small amount of food