APEA Orthopedics Pharmacology Test Bank | Updated Questions & Answers Review with A+ Solutions

APEA Orthopedics Pharmacology
Test Bank | Updated Questions &
Answers Review with A+ Solutions

• What is NOT a reason to discontinue allopurinol (Zyloprim)? -
✓✓Acute gout exacerbation


• What is the half-life elimination of colchicine (Colcrys)? -
✓✓Approximately 30 hours


• With which medication should caution be advised when using
salicylates? -✓✓Celecoxib (Celebrex)


• Which medication helps the kidneys excrete uric acid? -✓✓Probenecid


• How is acetaminophen (Tylenol) classified for osteoarthritic pain? -
✓✓Nonopioid analgesic


• For which condition is naproxen (Aleve) NOT indicated? -
✓✓Migraines


• What condition is baclofen (Lioresal) indicated for? -✓✓Multiple
sclerosis

, • What can the concomitant use of aspirin and NSAIDs cause? -
✓✓Abnormally high serum potassium levels


• What are two black box warnings for ibuprofen (Motrin)? -
✓✓Cardiovascular thrombotic events and gastrointestinal bleeding


• What is the best initial medication for acute gout in a patient with a
creatinine clearance of 50 mL/min? -✓✓Colchicine


• How does acetaminophen (Tylenol) work to reduce pain? -
✓✓Inhibiting the synthesis of prostaglandins in the central nervous
system and blocking pain impulse generation peripherally


• What is the generic name for Lioresal? -✓✓Baclofen


• What is the mechanism of action of Ketorolac? -✓✓Decreasing the
synthesis of prostaglandins by reversibly inhibiting COX-1 and COX-2
enzymes


• Which adverse event is NOT related to colchicine? -✓✓Pancreatitis


• What is the recommended therapy for low back pain when NSAIDs are
contraindicated? -✓✓Acetaminophen (Tylenol)