APPLIED PATHOPHYSIOLOGY A CONCEPTUAL APPRO
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ACH TO THE = = =======
MECHANISMS OF DISEASE 4TH EDITION = = = = ==
(Answers are at the End of Each Chapter)
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Chapter 1: Introduction to Pathophysiology
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1. The nucleus
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A) is the site of protein synthesis
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B) contains the genetic code = = = =
C) transforms cellular energy = = =
D) initiates aerobic metabolism = = =
2. Although energy is not made in mitochondria, they are known as the power plants
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of the cell because they:
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A) contain RNA for protein synthesis. = = = = =
B) utilize glycolysis for oxidative energy.
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C) extract energy from organic compounds.
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D) store calcium bonds for muscle contractions.
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3. Although the basic structure of the cell plasma membrane is formed by a lipid
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bilayer, most of the specific membrane functions are carried out by: A) bound and
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transmembrane proteins. = =
B) complex, long carbohydrate chains. = = = =
C) surface antigens and hormone receptors.
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D) a gating system of selective ion channels.
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4. To effectively relay signals, cell-to-
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cell communication utilizes chemical messenger systems that:
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A) displace surface receptor proteins. = = = =
B) accumulate within cell gap junctions. = = = = =
C) bind to contractile microfilaments.
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D) release secretions into extracellular fluid.
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,Test bank for Applied pathophysiology a conceptual approach to the mechanisms of disease 4th Edition.
5. Aerobic metabolism, also known as oxidative metabolism, provides energy by:
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A) removing the phosphate bonds from ATP. = = = = = =
B) combining hydrogen and oxygen to form water. = = = = = = =
C) activating pyruvate stored in the cytoplasm. = = = = = =
D) breaking down glucose to form lactic acid. = = = = = = =
6. Exocytosis, the reverse of endocytosis, is important in
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into the extracellular fluid.
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A) Engulfing and ingesting fluid and proteins for transport
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B) Killing, degrading, and dissolving harmful microorganisms
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C) Removing cellular debris and releasing synthesized substances
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D) Destruction of particles by lysosomal enzymes for secretion = = = = = = = =
7. The process responsible for generating and conducting membrane potentials is: A
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) diffusion of current-carrying ions.
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B) millivoltage of electrical potential. = = = =
C) polarization of charged particles. = = = =
D) ion channel neurotransmission.
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8. Epithelial tissues are classified according to the shape of the cells and the nu
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mber of layers. Which of the following is a correctly matched description a
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nd type of epithelial tissue?
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A) Simple epithelium: cells in contact with intercellular matrix; some do not e
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xtend to surface = = =
B) Stratified epithelium: single layer of cells; all cells rest on basement membr
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ane =
C) Glandular epithelium: arise from surface epithelia and underlying connecti
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ve tissue = =
D) Pseudostratified epithelium: multiple layers of cells; deepest layer rests on = = = = = = = = = =
basement membrane = =
9. Connective tissue contains fibroblasts that are responsible for: A)
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providing a fibrous framework for capillaries.
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B) synthesis of collagen, elastin, and reticular fibers.
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,Test bank for Applied pathophysiology a conceptual approach to the mechanisms of disease 4th Edition.
C) forming tendons and the fascia that covers muscles.
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D) filling spaces between tissues to keep organs in place.
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10. Although all muscle tissue cells have some similarities, smooth muscle (also kno
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wn as involuntary muscle) differs by:
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A) having dense bodies attached to actin filaments.
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B) containing sarcomeres between Z lines and M bands.
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C) having rapid contractions and abundant cross-striations.
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D) contracting in response to increased intracellular calcium.
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11. Which of the following aspects of the function of the nucleus is performed by ribo
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somal RNA (rRNA)? = = =
A) Copying and carrying DNA instructions for protein synthesis
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B) Carrying amino acids to the site of protein synthesis
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C) Providing the site where protein synthesis occurs
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D) Regulating and controlling protein synthesis
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12. Breakdown and removal of foreign substances and worn-
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out cell parts are performed by which of the following organelles?
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A) Lysosomes =
B) Golgi apparatus = =
C) Ribosomes =
D) Endoplasmic reticulum (ER) = = =
13. Impairment in the function of peroxisomes would result in: A)
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inadequate sites for protein synthesis.
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B) an inability to transport cellular products across the cell membrane.
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C) insufficient energy production within a cell.= = = = = =
D) accumulation of free radicals in the cytoplasm. = = = = = = =
14. After several months of trying to conceive, a couple is undergoing fertility testi
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ng. Semen analysis indicates that the mans sperm have decreased motility, a fi
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nding that is thought to underlie the couples inability to become pregnant.
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, Test bank for Applied pathophysiology a conceptual approach to the mechanisms of disease 4th Edition.
Which of the following cellular components may be defective within the mans s
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perm? =
A) Ribosomes =
B) Microtubules =
C) Mitochondria =
D) Microfilaments =
15. Which of the following statements is true of glycolysis? A)
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Glycolysis requires oxygen.
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B) Glycolysis occurs in cells without mitochondria. = = = = = =
C) Glycolysis provides the majority of the bodys energy needs.
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D) Glycolysis produces energy, water, and carbon dioxide. = = = = = = =
16. Which of the following membrane transport mechanisms requires the greatest am
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ount of energy?
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A) Facilitated diffusion = =
B) Passive transport = =
C) Vesicular transport = =
D) Simple diffusion = =
17. A male patient with a diagnosis of type 1 diabetes mellitus is experiencing hyper
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glycemia because he lacks sufficient insulin to increase the availability of gluc
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ose transporters in his cell membranes. Consequently, his cells lack intracellula
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r glucose and it accumulates in his blood. Which of the following processes wo
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uld best allow glucose to cross his cell membranes?
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A) Facilitated diffusion = =
B) Simple diffusion = =
C) Secondary active transport = = =
D) Endocytosis =
18. Which of the following statements is true of skeletal muscle cells?
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A) Skeletal muscle cells each have an apical, lateral, and basal surface.
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B) They are closely apposed and are joined by cell-to-
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cell adhesion molecules.
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