Chemotherapy & Biotherapy Certification Exam – Study Guide and Practice Questions Page 1 2026-03-30
Chemotherapy &
Biotherapy Certification
Exam – Study Guide and
Practice Questions
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Chemotherapy Biotherapy Certification Exam
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
chemo- injects chemo directly into the subarachnoid space so it
reaches the CNA
-leukemia and lymphoma spreading to CNS since most chemo does not
cross blood brain barrier
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine can
be given IT
-IT hydrocorisone given at same time to reduce inflammation
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
time- IVP not reommended
vinblastine -dilute in 25-50 ns
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines: interfere
with enzymes for DNA to replicate, work phases of the cell cycle
lifetime dose limites because they are cardiotoxic
-daunorubicin, doxorubicin, epirubicin, idarubicin
nonanthracycline: actinomycin, mitomycin, bleomycin
5. doxorubicin - ANS ✔vesicant
extravasation possible- must eval cardiac funciton, ongoing cardiac
monitoring, hypersensitivity risk
Chemotherapy Biotherapy Certification
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-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
impairment, secondary cancer
-cardiac: SOB< skipped beats, weight gain
-myelosuppress: oral temp daily, report >100.5
GI: nausea vomiting diarrhea, inspect mucosa
neuro: numbness/ tingling, burning
GU: change in color of urine
6. dexrazoxane - ANS ✔cardiac protectant given before
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
-can cause hypersensitivity, skin reaction
-report SOB< skin issues, protect from sun
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
induced nausea and vomiting
-lead to dehydration, dec functional status, increased costs and withdrawal
from treatment
-70% patient will experience.
RISK Factors: younger, history of low alcohol consumption, female,
morning/ motion sickness
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
daarbazine, mechlorethamine, streptozocin
Chemotherapy Biotherapy Certification
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Chemotherapy &
Biotherapy Certification
Exam – Study Guide and
Practice Questions
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_
Chemotherapy & Biotherapy Certification Exam – Study Guide and Practice Questions 1 Chemotherapy & Biotherapy Certification Exam – Study Guide and Practice Questions.pdf
,Chemotherapy Biotherapy Certification Exam Page 2 2026-03-30
1
Chemotherapy Biotherapy Certification Exam
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
chemo- injects chemo directly into the subarachnoid space so it
reaches the CNA
-leukemia and lymphoma spreading to CNS since most chemo does not
cross blood brain barrier
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine can
be given IT
-IT hydrocorisone given at same time to reduce inflammation
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
time- IVP not reommended
vinblastine -dilute in 25-50 ns
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines: interfere
with enzymes for DNA to replicate, work phases of the cell cycle
lifetime dose limites because they are cardiotoxic
-daunorubicin, doxorubicin, epirubicin, idarubicin
nonanthracycline: actinomycin, mitomycin, bleomycin
5. doxorubicin - ANS ✔vesicant
extravasation possible- must eval cardiac funciton, ongoing cardiac
monitoring, hypersensitivity risk
Chemotherapy Biotherapy Certification
Chemotherapy Biotherapy Certification Exam 2 Chemotherapy Biotherapy Certification Exam.pdf
, Chemotherapy Biotherapy Certification Exam Page 3 2026-03-30
2
-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
impairment, secondary cancer
-cardiac: SOB< skipped beats, weight gain
-myelosuppress: oral temp daily, report >100.5
GI: nausea vomiting diarrhea, inspect mucosa
neuro: numbness/ tingling, burning
GU: change in color of urine
6. dexrazoxane - ANS ✔cardiac protectant given before
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
-can cause hypersensitivity, skin reaction
-report SOB< skin issues, protect from sun
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
induced nausea and vomiting
-lead to dehydration, dec functional status, increased costs and withdrawal
from treatment
-70% patient will experience.
RISK Factors: younger, history of low alcohol consumption, female,
morning/ motion sickness
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
daarbazine, mechlorethamine, streptozocin
Chemotherapy Biotherapy Certification
Chemotherapy Biotherapy Certification Exam 3 Chemotherapy Biotherapy Certification Exam.pdf
