Pathophysiology for the
Health Professions 7th
Edition VanMeter
1
Chapter 01: Introduction to Pathophysiology
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
MULTIPLE CHOICE
1. Which of the following would be the most likely cause of an iatrogenic disease?
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a. An inherited disorder
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b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment
L L L L L L L
ANS: C
2. The manifestations of a disease are best defined as the
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a. subjective feelings of discomfort during a chronic illness.
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b. signs and symptoms of a disease.
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c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection.
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ANS: B
3. The best definition of the term prognosis is the
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a. precipitating factors causing an acute episode. L L L L L
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. L L L L
ANS: C
,4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee L L L
b. Fever
c. Pain in the neck L L L
d. Red rash on the face ANS: B
L L L L L
5. Etiology is defined as the study of the
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a. causes of a disease. L L L
b. course of a disease. L L L
c. expected complications of a disease. L L L L
d. manifestations of a disease. L L L
ANS: A
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as a.
L L L L L L L L L L L L L L L L L L
hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D
7. A change in a tissue marked by cells that vary in size and shape and show increased mitotic
L L L L L L L L L L L L L L L L L
L figures would be called
L L L
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy. ANS: C L
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called a.
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apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis. ANS: B L
9. When a group of cells in the body dies, the change is called
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a. ischemia.
b. gangrene.
, c. hypoxia.
d. necrosis.
ANS: D
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cells
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undergoing a.
L L hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A
11. The term cancer refers to
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. ANS: D L L
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells L L L L L L
b. Ischemic damage to cells L L L
c. Liquefaction of necrotic tissue L L L
d. Preprogrammed cell self-destruction L L
ANS: D
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. L L L L L L L
b. Damaged cells may be able to repair themselves. L L L L L L L
c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death. ANS: B
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14. Caseation necrosis refers to an area where
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a. cell proteins have been denatured.
L L L L