NR565 MIDTERM ULTIMATE CRAM SHEET:
KEY CONCEPTS & MEDICATIONS | 2026
COMPLETE SOLUTIONS ~ CHAMBERLAIN
UNIVERSITY.
NR565 MIDTERM ULTIMATE CRAM SHEET (Weeks 1–4)
WEEK 1 – FOUNDATIONS
Prescriptive Authority: State law + Nurse Practice Act
Outside scope = Legal & Ethical violation
Valid Prescription: Patient, Drug (generic), Dose, Route, Frequency, Quantity, Refills, Prescriber
credentials & signature
First-pass metabolism: Oral drugs only LOW oral bioavailability
ONLY FREE (unbound) drug is active
CYP450: Inhibitors HOLD it in drug levels; Inducers BURN it up drug levels
Half-life: Time to drug by 50%; long half-life accumulation
Pregnancy categories: A safest, B preferred, C caution, D risk but benefit, X NEVER
Category X MUST KNOW: Isotretinoin, Thalidomide, Warfarin, Methotrexate, Misoprostol
Boxed warnings = risk of serious injury or death
Infants & Elderly: immature vs declining organs toxicity
Pediatric DO NOT USE: CAT-FAPPS (Chloramphenicol, Aspirin, Tetracyclines, Fluoroquinolones,
Promethazine, Sulfonamides, Codeine, Tramadol)
KEY CONCEPTS & MEDICATIONS | 2026
COMPLETE SOLUTIONS ~ CHAMBERLAIN
UNIVERSITY.
NR565 MIDTERM ULTIMATE CRAM SHEET (Weeks 1–4)
WEEK 1 – FOUNDATIONS
Prescriptive Authority: State law + Nurse Practice Act
Outside scope = Legal & Ethical violation
Valid Prescription: Patient, Drug (generic), Dose, Route, Frequency, Quantity, Refills, Prescriber
credentials & signature
First-pass metabolism: Oral drugs only LOW oral bioavailability
ONLY FREE (unbound) drug is active
CYP450: Inhibitors HOLD it in drug levels; Inducers BURN it up drug levels
Half-life: Time to drug by 50%; long half-life accumulation
Pregnancy categories: A safest, B preferred, C caution, D risk but benefit, X NEVER
Category X MUST KNOW: Isotretinoin, Thalidomide, Warfarin, Methotrexate, Misoprostol
Boxed warnings = risk of serious injury or death
Infants & Elderly: immature vs declining organs toxicity
Pediatric DO NOT USE: CAT-FAPPS (Chloramphenicol, Aspirin, Tetracyclines, Fluoroquinolones,
Promethazine, Sulfonamides, Codeine, Tramadol)
