LECOM Seton Hill Histology Exam 1 Stains with correct answers 100% 2026
LECOM Seton Hill Histology Exam 1 Stains with correct answers 100% 2026 Periodic Acid-Schiff - Correct Answer Magenta: glycogen and carb-rich molecules, tests for Von Gierke's. Haemotoxylin - Correct Answer Purple, stains acids. Eosin - Correct Answer Pink, stains bases. Prussian Blue - Correct Answer Blue, stains iron molecules Congo Red - Correct Answer Red, stain amyloid proteins in beta-pleated sheets like prions. Plane polarized light can see greens? Trichrome - Correct Answer Red, blue/green, and yellow. Stains collagen fibers Reticulin - Correct Answer Can be silver. Dyes reticulin fibers (type III collagen). DAB - Correct Answer Immunochemistry Ab. Binds targeted Ab and releases light. Cytokeratin - Correct Answer Immunochemistry for Epithelial cells. Vimentin - Correct Answer Immunochemistry for mesenchymal cells. Desmin - Correct Answer Immunohistochemical stain for Muscle. Prostate Specific Antigen - Correct Answer Immunohistochemical stain for prostate epithelium. HER2/neu - Correct Answer Immunohistochemical stain for breast cancer (carcinomas). Cell membrane p53 - Correct Answer Stains cancerous nuclei. Von Gierke's disease - Correct Answer glycogen storage disease (G6Pase deficiency) Progeria - Correct Answer Rapid aging caused by Nuclear Lamin A mutant Smooth ER (Detoxification) - Correct Answer Hydroxylation rxn, conjugation rxn, makes toxin water soluble and excrete-able I-cell disease - Correct Answer No Mannose-6-P added to proteins, lysosomal storage disease Hyperproinsulinemia - Correct Answer insulin protein not cleaved properly, presents as diabetic bc insulin not functioning Gaucher disease - Correct Answer Glucocerebroside accumulation due to enzyme mutation Zellweger syndrome - Correct Answer Defective peroxisome biogenesis = defective proxisomal oxidation. Inability to breakdown LC FAs due to peroxisome defect. FAs are cut short and sent to mitochondria. hepatomeg, Mental Retardation, Infantile death. Severe mitochondrial myopathy - Correct Answer disease of the muscle due to mitochondria not functioning correctly microtubules - Correct Answer tubulin, biggest of three, chromosomal movement and intracellular vesicle and organelle transport, kinesin, dynein, associated with herpes intermediate filaments - Correct Answer middle size, cytokeratines( epithelial) Desmin ( smooth muscle), Vimentin (mesenchymal organs) GFA (astrocytes) Microfilaments - Correct Answer smallest, actin, sliding movement and polymerization movement simple squamous epithelium - Correct Answer diffusion and filtration, lines blood vessels endothelium, and serous membrane (mesothelium), loop of henle simple cuboidal epithelium - Correct Answer secretion and absorption, lines ducts of glands, walls of kidney tubules pseudostratified columnar epithelium - Correct Answer tissue that consists of a single layer of irregularly shaped and sized cells that give the appearance of multiple layers; found in ducts of certain glands and the upper respiratory tract Primary cilia diskenesia - Correct Answer Immotile cilia syndrome due to absent dynein arms Occulding junctions - Correct Answer Tight junction at top of lateral border, occludins and claudins belt desmosome (zonula adherens) - Correct Answer E-cadherin, fascia adherens in cardiac muscle Desmosomes - Correct Answer spot attachments along lateral surface Gap junctions - Correct Answer connect two cells chemically Hemi-desmosomes - Correct Answer Basal, anchors intermediate cytoskeleton to basal lamina Focal contacts - Correct Answer basal, anchor actin
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