Pharmaceutics Exam 4 Practice Questions With Correct Answers

Pharmaceutics Exam 4 Practice || || || ||




Questions With Correct Answers || || || ||




Which of the following is not a pharmaceutical semisolid?
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A. Ointment
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B. Cream
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C. Foam
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D. Tablet
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E. None of the above - CORRECT ANSWER(S)✔✔Answer:
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D
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Explanation: I hope you know that tablets are solids.
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Other semisolids include pastes, gels, and suppositories
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What dosage form is incorrectly paired with a route of
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application?


A. Suppository : Body cavity
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B. Nasal : Skin Surface
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C. Dermal : Skin Surface
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,D. Ophthalmic : Mucous Membranes - CORRECT
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ANSWER(S)✔✔Answer: B ||




Explanation: Nasal drugs are applied to mucous || || || || || || ||



membranes.


Which of the following are effects we want to elicit when
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applying a semisolid to the skin?
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A. Effect on the skin surface (protective film)
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B. Effect within the stratum corneum layer (reservoir or
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depot effect)
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C. Deep-seated effect requiring penetration into the
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epidermis and dermis || ||




D. Systemic effect
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E. All of the above - CORRECT ANSWER(S)✔✔Answer: E
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Explanation: This is true. || || ||




What is the preferred method of delivery of a drug
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through the skin? || ||




A. Through the epidermis (diffusion)
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,B. Along hair follicular ducts and sweat glands -
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CORRECT ANSWER(S)✔✔Answer: A || ||




Explanation: While moving along hair particles bypasses || || || || || || ||



the stratum corneum, there is very little area of
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pores/hair for distribution (much lower proportion than
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the skin as a whole).
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Which of the following are examples of dermatological
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factors that affect delivery of topical drugs?
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A. Absorption/penetration
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B. Emollient properties of the drug
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C. Freedom from irritant effect
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D. Ease of application/removal
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E. All of the above - CORRECT ANSWER(S)✔✔Answer: E
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Explanation: These all affect drug delivery. Other || || || || || || ||



examples of factors include the Effect on skin function
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and Miscibility/compatibility with skin secretions.
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What biological factor does not significantly affect
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dermal penetration? ||

, A. Old skin age
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B. Blood flow
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C. Skin metabolism
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D. Skin hydration
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E. Skin pH - CORRECT ANSWER(S)✔✔Answer: A
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Explanation: While skin does change with old age, it does || || || || || || || || ||



not appear to affect drug delivery significantly. However,
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skin function is reduced in young children (SA to body
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ratio is high). Temperature of skin also affects
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penetration.


True/False: Dermal drug delivery is an excellent || || || || || || ||



alternative route of administration for geriatric patients.
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- CORRECT ANSWER(S)✔✔Answer: True
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Which of the following are physicochemical factors tgat
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ubfkyebce dernak oebetratuib - CORRECT || || || || ||



ANSWER(S)✔✔I'm sorry, I am so tired || || || || ||




Which of the following are physicochemical factors that
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influence dermal penetration? || ||




A. Partition coefficient/lipophilicity
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