, Nursingmaterials
Table of Contents
Chapter 01 Cellular Biology 1
Chapter 02 Genes and Genetic Diseases 11
Chapter 03 Epigenetics and Disease 21
Chapter 04 Altered Cellular and Tissue Biology 25
Chapter 05 Fluids and Electrolytes, Acids and Bases 37
Chapter 06 Innate Immunity Inflammation and Wound Healing 47
Chapter 07 Adaptive Immunity 59
Chapter 08 Infection and Defects in Mechanisms of Defence 65
Chapter 09 Stress and Disease 76
Chapter 10 Biology of Cancer 81
Chapter 11 Cancer Epidemiology 87
Chapter 12 Cancer in Children and Adolescents 91
Chapter 13 Structure and Function of the Neurological System 94
Chapter 14 Pain, Temperature, Sleep, and Sensory Function 105
Chapter 15 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor
Function 117
Chapter 16 Disorders of the Central and Peripheral Nervous Systems and Neuromuscular
Junction 128
Chapter 17 Developmental Alterations of Neurological Function 140
Chapter 18 Mechanisms of Hormonal Regulation 148
Chapter 19 Alterations of Hormonal Regulation 157
Chapter 20 Structure and Function of the Hematological System 171
Chapter 21 Alterations of Hematological Function 178
Chapter 22 Developmental Alterations of Hematological Function 195
Chapter 23 Structure and Function of the Cardiovascular and Lymphatic Systems 203
Chapter 24 Alterations of Cardiovascular Function 214
Chapter 25 Developmental Alterations of Cardiovascular Function 234
Chapter 26 Structure and Function of the Pulmonary System 241
Chapter 27 Alterations of Pulmonary Function 250
Chapter 28 Developmental Alterations of Pulmonary Function 263
Chapter 29 Structure and Function of the Renal and Urological Systems 270
Chapter 30 Alterations of Renal and Urinary Tract Function 278
Chapter 31 Developmental Alterations of Renal and Urinary Tract Function 285
Chapter 32 Structure and Function of the Reproductive Systems 291
Chapter 33 Alterations of the Female Reproductive System 300
Chapter 34 Alterations of the Male Reproductive System 306
Chapter 35 Structure and Function of the Digestive System 311
Chapter 36 Alterations of Digestive Function 319
Chapter 37 Developmental Alterations of Digestive Function 332
Chapter 38 Structure and Function of the Musculoskeletal System 340
Chapter 39 Alterations of Musculoskeletal Function 349
Nursingmaterials
extra per year?
, Nursingmaterials
Chapter 40 Developmental Alterations of Musculoskeletal Function 359
Chapter 41 Structure, Function, and Disorders of the Integument 364
Chapter 42 Developmental Alterations of the Integument 374
Nursingmaterials
extra per year?
, tandingr-Kean,
Pathophysiology,
2023) Canadian Edition, 2nd Edition (Powe
_____________________________________________________________
Nursingmaterials
Chapter 01: Cellular Biology
: Huether and McCance’s Understandi ng Pathophysiology, Second
Canadian Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. The student notices it to have supercoiled
DNA with histones. What else would the student be expected to observe?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
nucleus; thus, the nucleus should be observed. A prokaryotic cell contains a single circular
chromosome and lacks organelles.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
The cell’s ability to produce energy is respiration. Communication involves maintenance of a
steady dynamic state, while metabolic absorption provides cellular nutrition, and secretion
allows for the delivery or release of new substances.
DIF: Cognitive Level: Remember REF: Cellular Functions
TOP: Physiological Integrity
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
the genetic information be contained?
a. Peroxisomes
b. Ribosomes
c. The nucleolus
d. Suspended in nucleoplasm
ANS: D
The region of the cell that contains genetic material, is the nucleoplasm contained within the
nucleus. The nucleolus, contained within the nucleus, is largely composed of ribosomes.
Peroxisomes contain digestive enzymes.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
______________________________________________________________________________________________
1|Page
Nursingmaterials
extra per year?
Table of Contents
Chapter 01 Cellular Biology 1
Chapter 02 Genes and Genetic Diseases 11
Chapter 03 Epigenetics and Disease 21
Chapter 04 Altered Cellular and Tissue Biology 25
Chapter 05 Fluids and Electrolytes, Acids and Bases 37
Chapter 06 Innate Immunity Inflammation and Wound Healing 47
Chapter 07 Adaptive Immunity 59
Chapter 08 Infection and Defects in Mechanisms of Defence 65
Chapter 09 Stress and Disease 76
Chapter 10 Biology of Cancer 81
Chapter 11 Cancer Epidemiology 87
Chapter 12 Cancer in Children and Adolescents 91
Chapter 13 Structure and Function of the Neurological System 94
Chapter 14 Pain, Temperature, Sleep, and Sensory Function 105
Chapter 15 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor
Function 117
Chapter 16 Disorders of the Central and Peripheral Nervous Systems and Neuromuscular
Junction 128
Chapter 17 Developmental Alterations of Neurological Function 140
Chapter 18 Mechanisms of Hormonal Regulation 148
Chapter 19 Alterations of Hormonal Regulation 157
Chapter 20 Structure and Function of the Hematological System 171
Chapter 21 Alterations of Hematological Function 178
Chapter 22 Developmental Alterations of Hematological Function 195
Chapter 23 Structure and Function of the Cardiovascular and Lymphatic Systems 203
Chapter 24 Alterations of Cardiovascular Function 214
Chapter 25 Developmental Alterations of Cardiovascular Function 234
Chapter 26 Structure and Function of the Pulmonary System 241
Chapter 27 Alterations of Pulmonary Function 250
Chapter 28 Developmental Alterations of Pulmonary Function 263
Chapter 29 Structure and Function of the Renal and Urological Systems 270
Chapter 30 Alterations of Renal and Urinary Tract Function 278
Chapter 31 Developmental Alterations of Renal and Urinary Tract Function 285
Chapter 32 Structure and Function of the Reproductive Systems 291
Chapter 33 Alterations of the Female Reproductive System 300
Chapter 34 Alterations of the Male Reproductive System 306
Chapter 35 Structure and Function of the Digestive System 311
Chapter 36 Alterations of Digestive Function 319
Chapter 37 Developmental Alterations of Digestive Function 332
Chapter 38 Structure and Function of the Musculoskeletal System 340
Chapter 39 Alterations of Musculoskeletal Function 349
Nursingmaterials
extra per year?
, Nursingmaterials
Chapter 40 Developmental Alterations of Musculoskeletal Function 359
Chapter 41 Structure, Function, and Disorders of the Integument 364
Chapter 42 Developmental Alterations of the Integument 374
Nursingmaterials
extra per year?
, tandingr-Kean,
Pathophysiology,
2023) Canadian Edition, 2nd Edition (Powe
_____________________________________________________________
Nursingmaterials
Chapter 01: Cellular Biology
: Huether and McCance’s Understandi ng Pathophysiology, Second
Canadian Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. The student notices it to have supercoiled
DNA with histones. What else would the student be expected to observe?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
nucleus; thus, the nucleus should be observed. A prokaryotic cell contains a single circular
chromosome and lacks organelles.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
The cell’s ability to produce energy is respiration. Communication involves maintenance of a
steady dynamic state, while metabolic absorption provides cellular nutrition, and secretion
allows for the delivery or release of new substances.
DIF: Cognitive Level: Remember REF: Cellular Functions
TOP: Physiological Integrity
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
the genetic information be contained?
a. Peroxisomes
b. Ribosomes
c. The nucleolus
d. Suspended in nucleoplasm
ANS: D
The region of the cell that contains genetic material, is the nucleoplasm contained within the
nucleus. The nucleolus, contained within the nucleus, is largely composed of ribosomes.
Peroxisomes contain digestive enzymes.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
______________________________________________________________________________________________
1|Page
Nursingmaterials
extra per year?
