Pass the PSA e-Book
Authors : William Brown & Kevin W Loudon & James Fisher & Laura B Marsland
,PSA e-Book, 1st Edition
Chapter 1: Basic Principles of Prescribing
Q1
A 72-year-old man with chronic kidney disease (eGFR 25 mL/min) is prescribed morphine
for pain.
What is the safest prescribing decision?
A. Prescribe standard-dose morphine
B. Avoid opioids completely
C. Prescribe reduced-dose morphine with monitoring
D. Switch to NSAIDs
E. Prescribe codeine at normal dose
Correct Answer: C
Clinical Reasoning
• Morphine metabolites accumulate in renal impairment → toxicity risk.
• Dose reduction + monitoring is safest.
Prescribing Safety Justification
• BNF-style: adjust dose in renal impairment; monitor sedation/respiratory
depression.
Incorrect Options
• A: Risk of accumulation → respiratory depression
• B: Pain untreated
• D: NSAIDs contraindicated in CKD
• E: Codeine also accumulates
Q2
A prescription chart reads: “Paracetamol 1 g QDS”.
,What is the main prescribing error?
A. Dose too high
B. Route missing
C. Frequency unsafe
D. Drug inappropriate
E. Legal requirement breached
Correct Answer: B
Reasoning
• Route (oral/IV) must be specified.
Safety Note
• Incomplete prescriptions = medication error risk.
Incorrect
• A: Dose acceptable
• C: QDS appropriate
• D: Drug appropriate
• E: Not primary issue
Q3
A patient reports a penicillin allergy (anaphylaxis). You prescribe co-amoxiclav.
Best interpretation?
A. Safe alternative
B. Minor risk
C. Serious prescribing error
D. Acceptable with monitoring
E. Only avoid IV form
Answer: C
Reasoning
• Co-amoxiclav contains amoxicillin → contraindicated.
, Safety
• Always check allergy status before prescribing.
Incorrect
All other options ignore life-threatening risk
Q4
Which is MOST important before prescribing a drug?
A. Cost
B. Patient preference
C. Indication
D. Drug availability
E. Brand name
Answer: C
Reasoning
• Prescribing must be clinically justified.
Q5
An elderly patient is prescribed diazepam for insomnia.
Main concern?
A. Ineffective drug
B. Risk of falls
C. Hepatotoxicity
D. Poor absorption
E. Cost
Answer: B
Reasoning
• Benzodiazepines → sedation, falls in elderly.
Q6