NR546 WEEK 2: TEST YOUR KNOWLEDGE QUIZ
QUESTIONS AND ANSWERS 100% CORRECT!!
Pharmacokinetics - ANSWER the study of what happens to a drug from the time of
administration until the parent drug and all metabolites leave the body
Pharmacokinetics concepts - ANSWER absorption
distribution
metabolism
excretion
Flockhart Table - ANSWER drug interactions that are mediated by cytochrome P450
enzymes
comprehensive list of drugs and the interactions related to the cytochrome P450 system
client factors that impact the effect of psychotropic medications - ANSWER -age
-diet
-smoking status
-other prescribed medications
-over-the-counter medications
*all impact drug metabolism
Neurotransmitters - ANSWER chemicals released by neurons to send communication
across synaptic clefts to other neurons
-impact human emotion and behavior
Many psychiatric disorders and client symptoms occur from an excess, deficiency, or
imbalance of _________ - ANSWER neurotransmitters
Neurotransmission: - ANSWER the chemical transmission of information between
neurons and their target cells
, -the chemicals, or neurotransmitters, are released from their transport vesicles to bind
with receptor sites to perform their duties, which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use (reuptake) or inactivated
and dissolved by enzymes
Excitatory neurotransmitters: - ANSWER increase the likelihood that the neuron will fire
an action potential
inhibitory neurotransmitters: - ANSWER decrease the likelihood that a neuron will fire
an action
Inhibitors: VISA CKGQ - ANSWER Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Ketoconazole
Grapefruit Juice
Quinidine
-decrease medication metabolism
Inducers: CRAP GPS - ANSWER Carbamazepine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas
-increase medication metabolism
neurotransmitters that may be responsible for a client's symptoms of depression -
ANSWER Imbalanced levels of acetylcholine, norepinephrine, serotonin, histamine, or
glutamate can contribute to symptoms of depression
client who is a poor metabolizer: - ANSWER has a lower concentration of the necessary
enzyme to metabolize a drug, which results in higher blood concentrations of the drug.
-increase the risk of side effects and adverse reactions
QUESTIONS AND ANSWERS 100% CORRECT!!
Pharmacokinetics - ANSWER the study of what happens to a drug from the time of
administration until the parent drug and all metabolites leave the body
Pharmacokinetics concepts - ANSWER absorption
distribution
metabolism
excretion
Flockhart Table - ANSWER drug interactions that are mediated by cytochrome P450
enzymes
comprehensive list of drugs and the interactions related to the cytochrome P450 system
client factors that impact the effect of psychotropic medications - ANSWER -age
-diet
-smoking status
-other prescribed medications
-over-the-counter medications
*all impact drug metabolism
Neurotransmitters - ANSWER chemicals released by neurons to send communication
across synaptic clefts to other neurons
-impact human emotion and behavior
Many psychiatric disorders and client symptoms occur from an excess, deficiency, or
imbalance of _________ - ANSWER neurotransmitters
Neurotransmission: - ANSWER the chemical transmission of information between
neurons and their target cells
, -the chemicals, or neurotransmitters, are released from their transport vesicles to bind
with receptor sites to perform their duties, which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use (reuptake) or inactivated
and dissolved by enzymes
Excitatory neurotransmitters: - ANSWER increase the likelihood that the neuron will fire
an action potential
inhibitory neurotransmitters: - ANSWER decrease the likelihood that a neuron will fire
an action
Inhibitors: VISA CKGQ - ANSWER Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Ketoconazole
Grapefruit Juice
Quinidine
-decrease medication metabolism
Inducers: CRAP GPS - ANSWER Carbamazepine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas
-increase medication metabolism
neurotransmitters that may be responsible for a client's symptoms of depression -
ANSWER Imbalanced levels of acetylcholine, norepinephrine, serotonin, histamine, or
glutamate can contribute to symptoms of depression
client who is a poor metabolizer: - ANSWER has a lower concentration of the necessary
enzyme to metabolize a drug, which results in higher blood concentrations of the drug.
-increase the risk of side effects and adverse reactions
