Immunology – MLS Study Guide and Practice Questions forImmunology
Medical Laboratory
– MLSScience
Study Guide
(1) and Practice Questions for Medical Laboratory Science (1).pdf 2026-03-21
Immunology – MLS Study
Guide and Practice
Questions for Medical
Laboratory Science
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_ 1
Page 1 of 40 Page 1
,Immunology - MLS Immunology - MLS.pdf 2026-03-21
2) In the anti-double-stranded DNA procedure, the C
antigen most commonly utilized is:
A) rat stomach tissue
B) mouse kidney tissue
C) Crithidia luciliae
D) Toxoplasma gondii
9) Systemic lupus erythematosus patients with active C
disease often have which of the following test results?
A) high titers of antimicrosomal antibodies
B) high titers of antimicrosomal antibodies
C) marked decrease in serum CH50
D) decreased serum immunoglobin levels
10) Which of the following is decreased in serum during C
the active stages of systemic lupus erythematosus?
A) anti-nuclear antibody
B) immune complexes
C) complement (C3)
D) anti-DNA
Page 2 of 40 2 Page 2
,Immunology - MLS Immunology - MLS.pdf 2026-03-21
11) A positive ANA with the pattern of anticentromere C
antibodies is most frequently seen in patients with:
A) rhematoid arthritis
B) systemic lupus erythematosus
C) CREST syndrome
D) Sjugren syndrome
12) In the indirect fluorescent anti-nuclear antibody test, D
a homogenous pattern indicates the presence of
antibody to:
A) RNP
B) Sm
C) RNA
D) DNA
13) In the direct fluorescent anti-nuclear antibody test, a B
speckled pattern may indicate the presence of antibody
to:
A) histone
B) Sm
C) RNA
D) DNA
Page 3 of 40 3 Page 3
, Immunology - MLS Immunology - MLS.pdf 2026-03-21
14) A patient has the following test result: C
ANA: +, 1:320; ASO: 50 Todd units; Complement:
decreased; RA: +
The above results could be seen in patients with:
A) rheumatic fever
B) rheumatoid arthritis
C) lupus erythematosus
D) glomerulonephritis
15) Autoantibodies in the absence of Sm are found in A
patients with:
A) mixed connective tissue disease
B) systemic lupus erythematosus
C) Crohn disease
D) multiple myeloma
Page 4 of 40 4 Page 4
Medical Laboratory
– MLSScience
Study Guide
(1) and Practice Questions for Medical Laboratory Science (1).pdf 2026-03-21
Immunology – MLS Study
Guide and Practice
Questions for Medical
Laboratory Science
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_ 1
Page 1 of 40 Page 1
,Immunology - MLS Immunology - MLS.pdf 2026-03-21
2) In the anti-double-stranded DNA procedure, the C
antigen most commonly utilized is:
A) rat stomach tissue
B) mouse kidney tissue
C) Crithidia luciliae
D) Toxoplasma gondii
9) Systemic lupus erythematosus patients with active C
disease often have which of the following test results?
A) high titers of antimicrosomal antibodies
B) high titers of antimicrosomal antibodies
C) marked decrease in serum CH50
D) decreased serum immunoglobin levels
10) Which of the following is decreased in serum during C
the active stages of systemic lupus erythematosus?
A) anti-nuclear antibody
B) immune complexes
C) complement (C3)
D) anti-DNA
Page 2 of 40 2 Page 2
,Immunology - MLS Immunology - MLS.pdf 2026-03-21
11) A positive ANA with the pattern of anticentromere C
antibodies is most frequently seen in patients with:
A) rhematoid arthritis
B) systemic lupus erythematosus
C) CREST syndrome
D) Sjugren syndrome
12) In the indirect fluorescent anti-nuclear antibody test, D
a homogenous pattern indicates the presence of
antibody to:
A) RNP
B) Sm
C) RNA
D) DNA
13) In the direct fluorescent anti-nuclear antibody test, a B
speckled pattern may indicate the presence of antibody
to:
A) histone
B) Sm
C) RNA
D) DNA
Page 3 of 40 3 Page 3
, Immunology - MLS Immunology - MLS.pdf 2026-03-21
14) A patient has the following test result: C
ANA: +, 1:320; ASO: 50 Todd units; Complement:
decreased; RA: +
The above results could be seen in patients with:
A) rheumatic fever
B) rheumatoid arthritis
C) lupus erythematosus
D) glomerulonephritis
15) Autoantibodies in the absence of Sm are found in A
patients with:
A) mixed connective tissue disease
B) systemic lupus erythematosus
C) Crohn disease
D) multiple myeloma
Page 4 of 40 4 Page 4
