1. Is the following statement correct: A virus con- N
tains DNA and RNA?
2. Is the following statement correct: Viruses must N
have either double-stranded DNA or RNA?
3. Is the following statement correct: All viruses N
have an envelop?
4. Is the following statement correct: Viruses can be N
propagated in rich artificial media without cells?
5. Most DNA viruses replicate in the Nucleus, Cytoplasm
whereas most RNA viruses replicate in the
.
6. Which DNA viruses replicate in the cytoplasm? Poxviridae, African Swine Fever
7. Which RNA viruses replicate in the nucleus? Orthomyxoviridae, Retroviridae,
Some Paramyxoviruses
8. What is the replication cycle of a virus (very simple Attachment, Penetration, Uncoat-
version)? ing, Synthesis of viral material, As-
sembly, Maturation, Release
9. A virus attaches to cell surface through ionic in- Attachment, Adsorption
teractions (temperature-independent)
10. Is the following statement correct: Cells without Y
receptors for a virus are not susceptible to the
virus.
11. Virus enters the cells through either fusion, endo- Penetration
cytosis, or directly crossing the membrane
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, Viral Replication Test Questions with Answers Rated A
12. What are the two ways enveloped viruses enter Fusion, Endocytosis
the cell?
13. Entry by fusion with the plasma membrane Fusion
14. Viral membrane fuses with the endosome mem- Endocytosis
brane when the endosomes become acidified.
Fusion of the endosome and virion membranes
results in releasing of internal components of the
virus
15. Is the following statement correct: Nonenveloped Y
viruses may cross the plasma membrane direct-
ly?
16. Nucleic acid has to be sufficiently uncoated be- Uncoating
fore virus replication can begin
17. In the final stage of the assembly pathway, most Assembly/Maturation
viruses go through a set of structural transitions
and/or biochemical modifications that transform
precursor particles into infectious particles
18. Cell lysis and Budding occur Release
19. Are all released viral particles infectious? N
20. All proteins in a mature virus even if the pro- Structural Protein
tein makes no contribution to the morphology or
rigidity of the virion
21. Viral proteins found in the cell but not packaged Non-Structural Protein
into the virion
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