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Pharmacotherapeutics for Advanced Practice
Nurse Prescribers
1. Nurse practitioner prescriptive authority is regulated by who?: The State
Board of Nursing for Each State
2. What is the benefits of having an APRN prescriber?: APRN's care for patients
more holistically and include patients in making decisions regarding their care
3. What does clinical judgement in prescribing include?: Factoring in the cost
of the particular
4. What is included in the criteria for choosing and effective drug for a
disorder?: Consulting nationally recognized guidelines for disease management
5. NP's thrive under the new health-care reform because of what?: NP's have the
ability to control care cost and improve patient outcome
6. Nutritional intake and lab results reflect hypoalbuminemia; why is this
important for prescribers?: The Distribution of drugs to target tissues may be affected
7. Drugs that have an significant first-pass effect what?: they are rapidly metabolized by
the liver and may have little if any desired action
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8. The route of excretion of a volatile drug will likely be?: Lungs
9. Medroxyprogesterone (Depo Provera) is prescribed IM to create storage
reservoir of the drug. What are storage reservoir?>: Increased the length of time a drug
is available and active
10. Why is Cephalexin given every 8 hours? What knowledge of the
drug does the NP know?: Half Life
11. Azithromycin doing requires that the first day's doing be twice those of
the other four day; This is considered a loading does. What is a loading dose?:
Rapidly actives drug levels in the therapeutic range
12. The point in time on the drug concentration curve that indicates the
first sign of a therapeutic effect is the:: Onset of action
13. Phenytoin required that a trough level be drawn. When and why are
peak and trough levels are done: To determine if a d rug is in the therapeutic range
14. Drugs that are receptor agonists may demonstrate what property?:
Concentrations will produce an adverse effect
15. Factors that affect gastric drug absorption include: Lipid solubility of the
drug
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16. Drugs that are receptors antagonists, such as beta-blockers, may cause
what?: An exaggerated response if abrupt discontinues
17. Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed: Are easily absorbed if they are nonionized
18. What is the combination effect when a medication is added to a
regimen for a synergistic effect?: Greater than the sum of the effects of each drug individually
19. Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow
therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3) Drugs that are administered more than once a day have greater
AA
Pharmacotherapeutics for Advanced Practice
Nurse Prescribers
1. Nurse practitioner prescriptive authority is regulated by who?: The State
Board of Nursing for Each State
2. What is the benefits of having an APRN prescriber?: APRN's care for patients
more holistically and include patients in making decisions regarding their care
3. What does clinical judgement in prescribing include?: Factoring in the cost
of the particular
4. What is included in the criteria for choosing and effective drug for a
disorder?: Consulting nationally recognized guidelines for disease management
5. NP's thrive under the new health-care reform because of what?: NP's have the
ability to control care cost and improve patient outcome
6. Nutritional intake and lab results reflect hypoalbuminemia; why is this
important for prescribers?: The Distribution of drugs to target tissues may be affected
7. Drugs that have an significant first-pass effect what?: they are rapidly metabolized by
the liver and may have little if any desired action
AA
,A
8. The route of excretion of a volatile drug will likely be?: Lungs
9. Medroxyprogesterone (Depo Provera) is prescribed IM to create storage
reservoir of the drug. What are storage reservoir?>: Increased the length of time a drug
is available and active
10. Why is Cephalexin given every 8 hours? What knowledge of the
drug does the NP know?: Half Life
11. Azithromycin doing requires that the first day's doing be twice those of
the other four day; This is considered a loading does. What is a loading dose?:
Rapidly actives drug levels in the therapeutic range
12. The point in time on the drug concentration curve that indicates the
first sign of a therapeutic effect is the:: Onset of action
13. Phenytoin required that a trough level be drawn. When and why are
peak and trough levels are done: To determine if a d rug is in the therapeutic range
14. Drugs that are receptor agonists may demonstrate what property?:
Concentrations will produce an adverse effect
15. Factors that affect gastric drug absorption include: Lipid solubility of the
drug
AA
,A
16. Drugs that are receptors antagonists, such as beta-blockers, may cause
what?: An exaggerated response if abrupt discontinues
17. Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed: Are easily absorbed if they are nonionized
18. What is the combination effect when a medication is added to a
regimen for a synergistic effect?: Greater than the sum of the effects of each drug individually
19. Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow
therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3) Drugs that are administered more than once a day have greater
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