COMSAE ALL
1st technology antihistamines - ANS-diphenhydramine, dimenhydrinate, chlorpheniramine
"en/ine" or "en/ate"
use: hypersensitive reaction motion unwell, sleep useful resource
AE: sedation, antimuscarinic, anti alpha adrenergic
2 bitemporal hemianopia - ANS-optic chiasm, pituitary tumor
2nd generation antihistimes - ANS-loratadine, fexofenadine, desloratadine, cetgirizine "adines"
use: hypersensitive reaction; a long way much less sedation than first gen bc dec access into
CNS
A beta lipoproteinemia - ANS-AR
chylomicrons VLDL LDL absent
deficiency within the B's ApoB-forty eight, and B100
toddlers: excessive fat malabsorption, steatorrhea, fail to thrive
later: retinitis pigments, spinocerebellar degeneration> Vit E deficiency, innovative ataxia,
acanthocytosis
Tx: massive dose oral Vitamin E; limit of lengthy chain fatty acids
Acanthocytosis - ANS-spiky spiny RBC
-indicative of pancreatitis, cirrhosis or abetalipoproteinemia
Acetaminophen - ANS-moa: reversibly inhibit COX, primarily CNS;
AE: OD>> hepatic necrosis; NAPQI depletes glutathione>> toxic byproducts liver; NAC=
antidote>> regenerate glutathione
Acidic amino acids - ANS-aspartic acid
glutamic acid
neg charged @ frame pH
Albinism - ANS-Defective tyrosinase (DEC DOPA> MELANIN)
ALKAPTONURIA - ANS-Congenital AR deficiency homogentisate oxidase (tyrosine> fumarate);
pigment forming homogentisic acid accumulate in tissue;
findings: bluish black CT; ear cartilage, sclerae (ochronosis); urine black on lengthen exposure
to air; poss debilitating arthralgia (poisonous to cartilage)
,Alkaptonuria - ANS-homogentisate oxidase deficiency (tyrosine> homogentisic acid>***
maleylacetoacetic acid> fumarate> TCA
alpha agonists must be averted in - ANS-closed angle glaucoma pts
Alpha galactosidase A (fAbrAy disease) - ANS-Fabr(a)y ailment
Early: triad: peripheral neuropathy, angiokeratomas, hypohidrosis
LatE: modern renal fail, CV sickness
buildup: Ceramide trihexoside; X hyperlink Recessive
assume Quinn Fabray gives to her youngsters (x hyperlink)
Amino Acids handiest L in proteins; glucogenic - ANS-I met his valentine, she's so sweet
(glycogenic)
methionine
histidine
valine
=gluconeogenic
AntiHistamines - ANS-Reversible inhibitor of H1 histamine receptors
Apo A-I - ANS-Activates LCAT (maturation of HDL)
chylomicron and HDL
Apo B-forty eight - ANS-mediate chylomicron secrete to lymphatics
precise to chylomicron and remnant!!
Apo C-II - ANS-lipoprotien lipase Cofactor that Catalyzes Cleavage
Chylomicron; VLDL, HDL
Apo E - ANS-mediate remnant uptake (Everything Except LDL)
Arginine - ANS--creatine
-urea
(BH4)>nitric oxid
Arylsulfatase A=Metaryl chromatic leukodystrophy - ANS-Metachromatic leukodystrophy
crucial and peripheral demyelination, w/ ataxia, dementia
AR
, buildup Cerebroside sulfate
Axillary nerve C5-C6 - ANS-flat deltoid; loss arm abduction, loss sensation over deltoid and
lateral arm
B-100 - ANS-bind LDL receptor
wished on all of the density DL's except High (HDL)
VLDL, IDL, LDL
Baroreceptors - ANS-hypotension: dec arterial pressure, dec stretch, dec afferent receptor firing,
growth efferent sympathetic firing, dec efferent parasympathetic stimulation>> vasoconstriction>
inc HR/contractility/BP
response to severe hemorrhage
Basic - ANS-Histidine
Arginine
Lysine
(arg maximum primary); His no price frame pH; Arg and His are required in the course of
periods of increase; Arg and Lys are increase in histones
Beta blockers: timolol, betaxolol, carteolol - ANS-dec AH synthesis; no scholar/imaginative and
prescient changes
Beta oxidation mediated by - ANS-acyl coA dehydrogenases
Bronchiectasis - ANS-continual necrotizing infection bronchi>> perm dilated airways, purulent
sputum, recurrent infecting, hemoptysis, virtual clubbing;
assoc: obstruction, negative ciliary motility (Kartagener syndrome, smoking) CF, allergic
bronchopulmonary aspergillosis
Buproprion - ANS-Atypical antidepressants
inhibit NE and dopamine reuptake
use smoking cessation
Toxicity: tachy, insomnia, headache, seizure in anorexic/bulimic pts; may additionally alleviate
sexual dysfxn
Buspirone - ANS-stimulate 5HT1A receptors
Generalized tension disorder, no sedation, addict, tolerance; 1-2 weeks to paintings; no engage
alcohol
1st technology antihistamines - ANS-diphenhydramine, dimenhydrinate, chlorpheniramine
"en/ine" or "en/ate"
use: hypersensitive reaction motion unwell, sleep useful resource
AE: sedation, antimuscarinic, anti alpha adrenergic
2 bitemporal hemianopia - ANS-optic chiasm, pituitary tumor
2nd generation antihistimes - ANS-loratadine, fexofenadine, desloratadine, cetgirizine "adines"
use: hypersensitive reaction; a long way much less sedation than first gen bc dec access into
CNS
A beta lipoproteinemia - ANS-AR
chylomicrons VLDL LDL absent
deficiency within the B's ApoB-forty eight, and B100
toddlers: excessive fat malabsorption, steatorrhea, fail to thrive
later: retinitis pigments, spinocerebellar degeneration> Vit E deficiency, innovative ataxia,
acanthocytosis
Tx: massive dose oral Vitamin E; limit of lengthy chain fatty acids
Acanthocytosis - ANS-spiky spiny RBC
-indicative of pancreatitis, cirrhosis or abetalipoproteinemia
Acetaminophen - ANS-moa: reversibly inhibit COX, primarily CNS;
AE: OD>> hepatic necrosis; NAPQI depletes glutathione>> toxic byproducts liver; NAC=
antidote>> regenerate glutathione
Acidic amino acids - ANS-aspartic acid
glutamic acid
neg charged @ frame pH
Albinism - ANS-Defective tyrosinase (DEC DOPA> MELANIN)
ALKAPTONURIA - ANS-Congenital AR deficiency homogentisate oxidase (tyrosine> fumarate);
pigment forming homogentisic acid accumulate in tissue;
findings: bluish black CT; ear cartilage, sclerae (ochronosis); urine black on lengthen exposure
to air; poss debilitating arthralgia (poisonous to cartilage)
,Alkaptonuria - ANS-homogentisate oxidase deficiency (tyrosine> homogentisic acid>***
maleylacetoacetic acid> fumarate> TCA
alpha agonists must be averted in - ANS-closed angle glaucoma pts
Alpha galactosidase A (fAbrAy disease) - ANS-Fabr(a)y ailment
Early: triad: peripheral neuropathy, angiokeratomas, hypohidrosis
LatE: modern renal fail, CV sickness
buildup: Ceramide trihexoside; X hyperlink Recessive
assume Quinn Fabray gives to her youngsters (x hyperlink)
Amino Acids handiest L in proteins; glucogenic - ANS-I met his valentine, she's so sweet
(glycogenic)
methionine
histidine
valine
=gluconeogenic
AntiHistamines - ANS-Reversible inhibitor of H1 histamine receptors
Apo A-I - ANS-Activates LCAT (maturation of HDL)
chylomicron and HDL
Apo B-forty eight - ANS-mediate chylomicron secrete to lymphatics
precise to chylomicron and remnant!!
Apo C-II - ANS-lipoprotien lipase Cofactor that Catalyzes Cleavage
Chylomicron; VLDL, HDL
Apo E - ANS-mediate remnant uptake (Everything Except LDL)
Arginine - ANS--creatine
-urea
(BH4)>nitric oxid
Arylsulfatase A=Metaryl chromatic leukodystrophy - ANS-Metachromatic leukodystrophy
crucial and peripheral demyelination, w/ ataxia, dementia
AR
, buildup Cerebroside sulfate
Axillary nerve C5-C6 - ANS-flat deltoid; loss arm abduction, loss sensation over deltoid and
lateral arm
B-100 - ANS-bind LDL receptor
wished on all of the density DL's except High (HDL)
VLDL, IDL, LDL
Baroreceptors - ANS-hypotension: dec arterial pressure, dec stretch, dec afferent receptor firing,
growth efferent sympathetic firing, dec efferent parasympathetic stimulation>> vasoconstriction>
inc HR/contractility/BP
response to severe hemorrhage
Basic - ANS-Histidine
Arginine
Lysine
(arg maximum primary); His no price frame pH; Arg and His are required in the course of
periods of increase; Arg and Lys are increase in histones
Beta blockers: timolol, betaxolol, carteolol - ANS-dec AH synthesis; no scholar/imaginative and
prescient changes
Beta oxidation mediated by - ANS-acyl coA dehydrogenases
Bronchiectasis - ANS-continual necrotizing infection bronchi>> perm dilated airways, purulent
sputum, recurrent infecting, hemoptysis, virtual clubbing;
assoc: obstruction, negative ciliary motility (Kartagener syndrome, smoking) CF, allergic
bronchopulmonary aspergillosis
Buproprion - ANS-Atypical antidepressants
inhibit NE and dopamine reuptake
use smoking cessation
Toxicity: tachy, insomnia, headache, seizure in anorexic/bulimic pts; may additionally alleviate
sexual dysfxn
Buspirone - ANS-stimulate 5HT1A receptors
Generalized tension disorder, no sedation, addict, tolerance; 1-2 weeks to paintings; no engage
alcohol
