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HESI A2 Anatomy & Physiology Practice Test | Actual Exam Questions & 100% Correct Answers | Latest Update 2026 | HESI Exam Prep

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Prepare with confidence for the HESI A2 Anatomy & Physiology Exam using this latest 2026 updated practice test. This resource includes actual exam-style questions with 100% correct answers, designed to closely match the format and difficulty of the real HESI A2 test. Perfect for nursing school applicants, this practice test helps you assess your knowledge, identify weak areas, and improve overall exam performance. What this resource offers: Full-length A&P practice test experience Realistic HESI A2 exam-style questions 100% correct answers for accurate study Efficient and focused exam preparation Topics covered include: Cell structure and function Skeletal and muscular systems Nervous and endocrine systems Cardiovascular and respiratory systems Digestive, urinary, and reproductive systems Homeostasis and system integration This study guide is ideal for students who want to test their knowledge, build confidence, and maximize their HESI A2 exam score.

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HESI A2 Anatomy & Physiology Practice
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HESI A2 Anatomy & Physiology Practice

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HESI A2 Anatomy & Physiology Practice Test | Actual
Exam Questions & 100% Correct Answers | Latest
Update 2026 | HESI Exam Prep

1. Which of the following structures is essential for maintaining an open tracheal
air passage in the posterior aspect of the trachea?




Proximity of the esophagus to the posterior tracheal wall

Respiratory epithelium with elastic fibers in the lamina propria

Cartilaginous rings

Connective tissue in the adventitia

Dense connective tissue in the submucosa

2. In a healthy individual, each heart beat is initiated by the:

sinoatrial node

atrioventricular node

bundle of his

, purkinje fibers
3. If a patient has damaged motor neurons, what physiological effect might they
experience?

Impaired movement

Improved coordination

Increased sensory perception

Enhanced reflexes

4. Of the following skull bones, which is the only bone that is capable of
movement?

Mandible

Temporal Bone

Sacrum

Frontal Bone

5. Describe the role of the placenta in hormone production during pregnancy.

The placenta is responsible for nutrient absorption only.

The placenta regulates blood pressure during pregnancy.

The placenta produces hormones that maintain the endometrium
and prepare the breasts for lactation.

The placenta produces red blood cells for the fetus.

6. The epidermis is composed of:

Connective

Muscle

Nerve

, Epithelial

7. What term is used to describe muscles that are under conscious control?

Cardiac muscles

Involuntary muscles

Smooth muscles

Voluntary muscles

8. If a patient has a fracture in the diaphysis of the humerus, what implications
might this have for their arm function?

It will only affect the range of motion at the shoulder joint.

It will have no effect on arm function.

It may impair the arm's ability to bear weight and perform
movements.

It will cause immediate swelling in the wrist.

9. If a patient has a condition affecting the pelvic cavity, which organs would
likely be impacted?

Lungs and heart

Stomach and intestines

Urinary bladder and internal reproductive organs

Kidneys and adrenal glands

10. What is the primary mineral that helps regulate fluid balance in the body?

Calcium

Sodium

, Magnesium

Potassium

11. What are the functional units of the kidney?

Nephrons

Alveoli

Glomeruli

Hepatocytes

12. What type of neurons transmit nerve impulses away from the central nervous
system (CNS)?

Sensory

Motor

Interneurons

Efferent

13. Describe the significance of the diaphysis in the structure of long bones like
the humerus.

The diaphysis is the region where blood vessels enter the bone.

The diaphysis is the end part of a long bone that articulates with
other bones.

The diaphysis is the area where bone growth occurs during
childhood.

The diaphysis is the long, tubular shaft of a long bone that provides
strength and support.
14. What is the basic structural and functional unit of all living organisms?

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