AP Bio Genetics, RNA, and DNA Practice Exam Questions and Answers Updated 2026

AP Bio Genetics, RNA, and DNA
Practice Exam Questions and
Answers Updated 2026
InBhisBtransformationBexperiments,BwhatBdidBGriffithBobserve?

a.BMutantBmiceBwereBresistantBtoBbacterialBinfections.

b.BMixingBaBheat-killedBpathogenicBstrainBofBbacteriaBwithBaBlivingBnonpathogenic

strainBcanBconvertBsomeBofBtheBlivingBcellsBintoBtheBpathogenicBform.

c.BMixingBaBheat-killedBnonpathogenicBstrainBofBbacteriaBwithBaBlivingBpathogenic

strainBmakesBtheBpathogenicBstrainBnonpathogenic.

d.BInfectingBmiceBwithBnonpathogenicBstrainsBofBbacteriaBmakesBthemBresistantBto

pathogenicBstrains.

e.BMiceBinfectedBwithBaBpathogenicBstrainBofBbacteriaBcanBspreadBtheBinfectionBtoBother

mice.B-BAnswerb



2.BWhatBdoesBtransformationBinvolveBinBbacteria?

a.BtheBcreationBofBaBstrandBofBDNABfromBanBRNABmolecule

b.BtheBcreationBofBaBstrandBofBRNABfromBaBDNABmolecule

c.BtheBinfectionBofBcellsBbyBaBphageBDNABmolecule

d.BtheBtypeBofBsemiconservativeBreplicationBshownBbyBDNA

e.BassimilationBofBexternalBDNABintoBaBcellB-BAnswere



3.BTheBfollowingBscientistsBmadeBsignificantBcontributionsBtoBourBunderstandingBofBtheBstruct
ureBand

functionBofBDNA.BPlaceBtheBscientists'BnamesBinBtheBcorrectBchronologicalBorder,BstartingBwit
hBtheBfirst

scientist(s)BtoBmakeBaBcontribution.

I.BAvery,BMcCarty,BandBMacLeod

II.BGriffith

III.BHersheyBandBChase

IV.BMeselsonBandBStahl

V.BWatsonBandBCrick

,a.BV,BIV,BII,BI,BIII

b.BII,BI,BIII,BV,BIV

c.BI,BII,BIII,BV,BIV

d.BI,BII,BV,BIV,BIII

e.BII,BIII,BIV,BV,BIB-BAnswerb



4.BCytosineBmakesBupB38%BofBtheBnucleotidesBinBaBsampleBofBDNABfromBanBorganism.BAppr
oximately

whatBpercentageBofBtheBnucleotidesBinBthisBsampleBwillBbeBthymine?

a.B12

b.B24

c.B31

d.B38

e.BItBcannotBbeBdeterminedBfromBtheBinformationBprovided.B-BAnswera



5.BChargaff'sBanalysisBofBtheBrelativeBbaseBcompositionBofBDNABwasBsignificantBbecauseBheB
wasBableBto

showBthat

a.BtheBrelativeBproportionBofBeachBofBtheBfourBbasesBdiffersBwithinBindividualsBofBa

species.

b.BtheBhumanBgenomeBisBmoreBcomplexBthanBthatBofBotherBspecies.

c.BtheBamountBofBABisBalwaysBequivalentBtoBT,BandBCBtoBG.

d.BtheBamountBofBriboseBisBalwaysBequivalentBtoBdeoxyribose.

e.BtransformationBcausesBproteinBtoBbeBbroughtBintoBtheBcell.B-BAnswerc



6.BWhichBofBtheBfollowingBcanBbeBdeterminedBdirectlyBfromBX-rayBdiffractionBphotographsBof

crystallizedBDNA?

a.BtheBdiameterBofBtheBhelix

b.BtheBrateBofBreplication

c.BtheBsequenceBofBnucleotides

d.BtheBbondBanglesBofBtheBsubunits

e.BtheBfrequencyBofBABvs.BTBnucleotidesB-BAnswera

,7.BWhyBdoesBtheBDNABdoubleBhelixBhaveBaBuniformBdiameter?

a.BPurinesBpairBwithBpyrimidines.

b.BCBnucleotidesBpairBwithBABnucleotides.

c.BDeoxyriboseBsugarsBbindBwithBriboseBsugars.

d.BNucleotidesBbindBwithBnucleosides.

e.BNucleotidesBbindBwithBnucleosideBtriphosphates.B-BAnswera



8.BWhatBkindBofBchemicalBbondBisBfoundBbetweenBpairedBbasesBofBtheBDNABdoubleBhelix?

a.Bhydrogen

b.Bionic

c.Bcovalent

d.Bsulfhydryl

e.BphosphateB-BAnswera



9.BInBanBanalysisBofBtheBnucleotideBcompositionBofBDNA,BwhichBofBtheBfollowingBwillBbeBfou
nd?

a.BAB=BC

b.BAB=BGBandBCB=BT

c.BAB+BCB=BGB+BT

d.BGB+BCB=BTB+BAB-BAnswerc



10.BReplicationBinBprokaryotesBdiffersBfromBreplicationBinBeukaryotesBforBwhichBofBtheseBreas
ons?

a.BTheBprokaryoticBchromosomeBhasBhistones,BwhereasBeukaryoticBchromosomesBdo

not.

b.BProkaryoticBchromosomesBhaveBaBsingleBoriginBofBreplication,BwhereasBeukaryotic

chromosomesBhaveBmany.

c.BTheBrateBofBelongationBduringBDNABreplicationBisBslowerBinBprokaryotesBthanBin

eukaryotes.

d.BProkaryotesBproduceBOkazakiBfragmentsBduringBDNABreplication,BbutBeukaryotes

doBnot.

, e.BProkaryotesBhaveBtelomeres,BandBeukaryotesBdoBnot.B-BAnswerb



11.BWhatBisBmeantBbyBtheBdescriptionB"antiparallel"BregardingBtheBstrandsBthatBmakeBupBDN
A?

a.BTheBtwistingBnatureBofBDNABcreatesBnonparallelBstrands.

b.BTheB5'BtoB3'BdirectionBofBoneBstrandBrunsBcounterBtoBtheB5'BtoB3'BdirectionBofBtheBother

strand.

c.BBaseBpairingsBcreateBunequalBspacingBbetweenBtheBtwoBDNABstrands.

d.BOneBstrandBisBpositivelyBchargedBandBtheBotherBisBnegativelyBcharged.

e.BOneBstrandBcontainsBonlyBpurinesBandBtheBotherBcontainsBonlyBpyrimidines.B-BAnswerb



12.BAnBOkazakiBfragmentBhasBwhichBofBtheBfollowingBarrangements?

a.Bprimase,Bpolymerase,Bligase

b.B3'BRNABnucleotides,BDNABnucleotidesB5'

c.B5'BRNABnucleotides,BDNABnucleotidesB3'

d.BDNABpolymeraseBI,BDNABpolymeraseBIII

e.B5'BDNABtoB3'B-BAnswerc



13.BWhichBenzymeBcatalyzesBtheBelongationBofBaBDNABstrandBinBtheB5'B3'Bdirection?

a.Bprimase

b.BDNABligase

c.BDNABpolymeraseBIII

d.Btopoisomerase

e.BhelicaseB-BAnswerc



14.BWhatBdeterminesBtheBnucleotideBsequenceBofBtheBnewlyBsynthesizedBstrandBduringBDNA
Breplication?

a.BtheBparticularBDNABpolymeraseBcatalyzingBtheBreaction

b.BtheBrelativeBamountsBofBtheBfourBnucleosideBtriphosphatesBinBtheBcell

c.BtheBnucleotideBsequenceBofBtheBtemplateBstrand

d.BtheBprimaseBusedBinBtheBreaction

e.BtheBarrangementBofBhistonesBinBtheBsugarBphosphateBbackboneB-BAnswerc