Antidysrhythmics and Blood Pressure Regulation: Key
Concepts and Mechanisms, Exams of Health sciences
-treats atrial and ventricular tachydysrhyhmias
-adverse effects: dysrhythmias, blood disorders, lupus like syndrome, vomiting,
diarrhea, prolonged QT interval, - ANSWERProcainamide (Pronestyl)
-Class Ib
-block sodium channels
-accelerate repolarization
-increase or decrease APD
-used for atrial and ventricular tachydysrhythmias caused by digitalis toxicity or
prolonged QT interval - ANSWERPhenytoin
-used to treat ventricular tachydysrhythmias
-raises ventricular fibrillation threshold
-can cause twitching, convulsions, confusion, respiratory depression, hypotension,
bradycardia, dysrhythmias - ANSWERLidocaine (Xylocaine)
-more pronounced effect on blocking sodium channels
-class Ic
-has little effect on APD or repolarization
-used for severe ventricular dysrhythmias
-first line drug in treatment of afib
-negative inotropic effect and depresses left ventricle
, -contraindicated in hypersensitivity, cardiogenic shock, second or third degree AV
block and non-life threatening dysrhythmias - ANSWERFlecainide
Beta blockers
-depressants for both supraventricular and ventricular dysrhythmias - ANSWERClass II
Antidysrhythmics
-cardioselective beta blocker
-contraindications severe bradycardia, second and third degree heart block,
cardiogenic shock or hypersensitivity - ANSWERAtenolol
-increase APD
-prolong repolarization of phase 3
-used for dysrhythmias that are difficult to treat - ANSWERClass III Antidysrhythmics
-one of the most effective drugs for controlling supraventricular and ventricular drugs
-drug of choice for controlling ventricular dysrhythmias
-adverse effects: corneal microdeposits, photophobia, dry eyes, halos, pulmonary
toxicity
contraindications: severe sinus bradycardia, second or third degree heart block,
hypersensitivity - ANSWERAmiodarone
Calcium channel blockers
-depress phase 4 repolarization
-reduce AV node conduction
-used for paroxysmal supraventricular tachycardia, rate controll for atrial fibrillation
and flutter - ANSWERClass IV
Concepts and Mechanisms, Exams of Health sciences
-treats atrial and ventricular tachydysrhyhmias
-adverse effects: dysrhythmias, blood disorders, lupus like syndrome, vomiting,
diarrhea, prolonged QT interval, - ANSWERProcainamide (Pronestyl)
-Class Ib
-block sodium channels
-accelerate repolarization
-increase or decrease APD
-used for atrial and ventricular tachydysrhythmias caused by digitalis toxicity or
prolonged QT interval - ANSWERPhenytoin
-used to treat ventricular tachydysrhythmias
-raises ventricular fibrillation threshold
-can cause twitching, convulsions, confusion, respiratory depression, hypotension,
bradycardia, dysrhythmias - ANSWERLidocaine (Xylocaine)
-more pronounced effect on blocking sodium channels
-class Ic
-has little effect on APD or repolarization
-used for severe ventricular dysrhythmias
-first line drug in treatment of afib
-negative inotropic effect and depresses left ventricle
, -contraindicated in hypersensitivity, cardiogenic shock, second or third degree AV
block and non-life threatening dysrhythmias - ANSWERFlecainide
Beta blockers
-depressants for both supraventricular and ventricular dysrhythmias - ANSWERClass II
Antidysrhythmics
-cardioselective beta blocker
-contraindications severe bradycardia, second and third degree heart block,
cardiogenic shock or hypersensitivity - ANSWERAtenolol
-increase APD
-prolong repolarization of phase 3
-used for dysrhythmias that are difficult to treat - ANSWERClass III Antidysrhythmics
-one of the most effective drugs for controlling supraventricular and ventricular drugs
-drug of choice for controlling ventricular dysrhythmias
-adverse effects: corneal microdeposits, photophobia, dry eyes, halos, pulmonary
toxicity
contraindications: severe sinus bradycardia, second or third degree heart block,
hypersensitivity - ANSWERAmiodarone
Calcium channel blockers
-depress phase 4 repolarization
-reduce AV node conduction
-used for paroxysmal supraventricular tachycardia, rate controll for atrial fibrillation
and flutter - ANSWERClass IV
