Test bank for Tietz Fundamentals of Clinical
mm mm mm mm mm mm
mm Chemistry and Molecular Diagnostics,
mm mm mm mm
8th Edition by Nader Rifai, PhD
mm mm mm mm mm mm
Chapters 1 - 49 mm mm mm mm
,Tietz mmFundamentals mmof mmClinical mmChemistry mmand mmMolecular mmDiagnostics mm8th m m Edition mmTest
mmBank
Table mmof mmcontents:
I. mmPrinciples mmOf mmLaboratory mmMedicine
Chapter mm1. mmClinical mmChemistry, mmMolecular mmDiagnostics, mmand mmLaboratory mmMedicine
Chapter mm2. mmSelection mmand mmAnalytical mmEvaluation mmof mmMethods mm— mmWith mmStatistical
mmTechniques
Chapter mm3. mmClinical mmEvaluation mmof mmMethods
Chapter mm4. mmEvidence-Based mmLaboratory mmMedicine
Chapter mm5. mmEstablishment mmand mmUse mmof mmReference mmValues
Chapter mm6. mmSpecimen mmCollection, mmProcessing, mmand mmOther mmPreanalytical mmVariables
Chapter mm7. mmQuality mmManagement
II. mmAnalytical mmTechniques mmAnd mmInstrumentation
Chapter mm8. mmPrinciples mmof mmBasic mmTechniques mmand mmLaboratory mmSafety
Chapter mm9. mmOptical mmTechniques
Chapter mm10. mmElectrochemistry mmand mmChemical mmSensors
Chapter mm11. mmElectrophoresis
Chapter mm12. mmChromatography
Chapter mm13. mmMass mmSpectrometry
Chapter mm14. mmEnzyme mmand mmRate mmAnalyses
Chapter mm15. mmImmunochemical mmTechniques
Chapter mm16 mmAutomation
Chapter mm17. mmPoint-of-Care mmInstrumentation
III. m m Analytes
Chapter mm18. mmAmino mmAcids, mmPeptides, mmand mmProteins
Chapter mm19. mmSerum mmEnzymes
Chapter mm20. mmTumor mmMarkers mmand mmCancer mmGenes
Chapter mm21. mmKidney mmFunction mmTests mm— mmCreatinine, mmGFR, mmUrea, mmand mmUric mmAcid
Chapter mm22. mmCarbohydrates
Chapter mm23. mmLipids, mmLipoproteins, mmApolipoproteins, mmand mmOther mmCardiac mmRisk mmFactors
Chapter mm24. mmElectrolytes mmand mmBlood mmGases
Chapter mm25. mmHormones
Chapter mm26. m m Catecholamines mmand mmSerotonin
Chapter mm27. m m Vitamins, mmTrace mmElements, mmNutritional mmAssessment
Chapter mm28. mmHemoglobin, mmIron, mmand mmBilirubin
Chapter mm29. mmPorphyrins mmand mmPorphyrias
Chapter mm30. mmTherapeutic mmDrugs mmand mmTheir mmManagement
Chapter mm31. mmClinical mmToxicology
Chapter mm32. m m Toxic mmMetals
IV. m m Pathophysiology
Chapter mm33. mmDiabetes
,Chapter mm34. m m Cardiovascular mmDisease
Chapter mm35. mmKidney mmDisease
Chapter mm36. m m Physiology mmand mmDisorders mmof mmWater, mmElectrolyte, mmand mmAcid-Base
mmMetabolism
Chapter mm37. mm mmLiver mmDisease
Chapter mm38. m m Gastrointestinal mmand mmPancreatic mmDiseases
Chapter mm39. mm mmDisorders mmof mmBone mmand mmMineral mmMetabolism
Chapter mm40. mm mmDisorders mmof mmthe mmPituitary mmGland
Chapter mm41. m m Disorders mmof mmthe mmAdrenal mmCortex
Chapter mm42. m m Thyroid mmDisorders
Chapter mm43. m m Reproduction-Related mmDisorders
Chapter mm44. mm mmPregnancy mmand mmPrenatal mmTesting
Chapter mm45. m m Newborn mmScreening mmand mmInborn mmErrors mmof mmMetabolism
Chapter mm46. mmPharmacogenetics
V. m m Molecular mmDiagnostics
Chapter mm47. mmPrinciples mmof mmMolecular mmBiology
Chapter mm48. mmNucleic mmAcid mmTechniques mmand mmApplications
Chapter mm49. mmGenomes mmand mmNucleic mmAcid mmAlterations
, Chapter mm01: mmClinical mmChemistry, mmMolecular mmDiagnostics, mmand mmLaboratory
mmMedicine mmTestmBank
m
MULTIPLE mmCHOICE
1. An mmindividual mmworking mmin mma mmclinical mmchemistry mmlaboratory mmis mmmarried mmto mma mmsales
mmrepresentative mmwho mmworks mmfor mma mmcompany mmthat mmsells mmchemistry mmlaboratory
mmsupplies. mmWhen mmthe mmlaboratory mmmanager mmrequests mma mmlist mmof mmneeded mmsupplies,
mmcost mmof mmsupplies, mmand mmvendors, mmthis mmindividual mmonlym
mrecommends mmthe mmspouse’s
mmcompany mmas mmthe mmvendor. mmThis mmis mmconsidered mmto mmbe mma(n):
a. accounting mmissue.
b. possible mmconflict mmof mminterest.
c. maintenance mmof mmconfidentiality mmissue.
d. problem mmwith mmresource mmallocation.
ANS: m m B
Concern mmhas mmbeen mmraised mmover mmthe mminterrelationships mmbetween mmpractitioners mmin mmthe
mmmedical mmfieldm and mmcommercial mmsuppliers mmof mmdrugs, mmdevices, mmequipment, mmetc., mmto
m
mmthe mmmedical mm profession.
Similarly, mmrelationships mmhave mmbeen mmscrutinized mmbetween mmclinical mmlaboratorians mmand
mmmanufacturers mmand mmproviders mmof mmdiagnostic mmequipment mmand mmsupplies. mmThese
mmconcerns mmled mmthe mmNational mmInstitutes mmof mmHealth mm(NIH) mmin mm1995 mmto mmrequire
mmofficial mminstitutional mmreview mmof mmfinancial mmdisclosure mmby mmresearchers mmand
mmmanagement mmof mmsituations mmin mmwhich mmdisclosure mmindicates mmpotentialm conflicts mmof
m
mminterest.
DIF: 1 REF: mm mm mmPage mm4-5 OBJ: m m 6 mm| mm7
2. A mmpatient mmvisits mmher mmphysician mmstating mmthat mmher mmprescribed mmpainkiller mmis mmnot
mmworking mmto mmreduce mmthe mmpain mmfollowing mmher mmrecent mmsurgery. mmA mmfriend mmof mmthe
mmpatient mmclaims mmthat mmthe mmsame mmpainkillermm―worked mmwonders‖ mmto mmreduce mmher mmpain
mmafter mmthe mmsame mmsurgery. mmThe mmphysician mmstates mmthat mmthe mmdifference mmin mmthe mmeffect
mmof mm the mmdrug mmmight mmbe mmcaused mmby , mmwhich mmis mmstudied mmin
mmpharmacogenetics.
a. epidemiology
b. an mminherited mmdisease
c. a mmconflict mmof mminterest
d. a mmgenetic mmvariation mmin mmdrug-metabolizing mmenzymes
ANS: m m D
Pharmacogenetics mmis mmthe mmstudy mmof mmthe mmgenetic mmvariation mmof mmdrug
mmmetabolism mmbetweenm individuals.
m
DIF: 1 REF: mm mm mmPage mm3 OBJ: m m 1
3. John mmworks mmin mma mmmolecular mmdiagnostics mmlaboratory mmand mmreceives mma mmblood
mmsample mmthat mmhas mmthe mmname mmof mma mmclose mmfriend mmprinted mmon mmthe mmbar-coded mmlabel.
mmThe mmgenetic mmtest mmthat mmis mmordered mmon mmthemmfriend’s mmsample mmwould mmprovide
mmdiagnostic mminformation mmabout mma mmdisorder mmthat mmhas mma mmpoor mmprognosis, mmand mmthe
mmtest mmis mmusually mmperformed mmby mmJohn. mmHe mmasks mma mmfellow mmemployee mmto mmanalyze
m
mthe mmsample mmfor mmhim mmand mmnot mmdivulge mmthe mmresults. mmThis mmethical mmissue mmconcerns:
a. confidentiality mmof mmpatient mmgenetic mmand mmmedical mminformation.
b. a mmconflict mmof mminterest.
c. resource mmallocation.
d. diagnostic mmaccuracy.
mm mm mm mm mm mm
mm Chemistry and Molecular Diagnostics,
mm mm mm mm
8th Edition by Nader Rifai, PhD
mm mm mm mm mm mm
Chapters 1 - 49 mm mm mm mm
,Tietz mmFundamentals mmof mmClinical mmChemistry mmand mmMolecular mmDiagnostics mm8th m m Edition mmTest
mmBank
Table mmof mmcontents:
I. mmPrinciples mmOf mmLaboratory mmMedicine
Chapter mm1. mmClinical mmChemistry, mmMolecular mmDiagnostics, mmand mmLaboratory mmMedicine
Chapter mm2. mmSelection mmand mmAnalytical mmEvaluation mmof mmMethods mm— mmWith mmStatistical
mmTechniques
Chapter mm3. mmClinical mmEvaluation mmof mmMethods
Chapter mm4. mmEvidence-Based mmLaboratory mmMedicine
Chapter mm5. mmEstablishment mmand mmUse mmof mmReference mmValues
Chapter mm6. mmSpecimen mmCollection, mmProcessing, mmand mmOther mmPreanalytical mmVariables
Chapter mm7. mmQuality mmManagement
II. mmAnalytical mmTechniques mmAnd mmInstrumentation
Chapter mm8. mmPrinciples mmof mmBasic mmTechniques mmand mmLaboratory mmSafety
Chapter mm9. mmOptical mmTechniques
Chapter mm10. mmElectrochemistry mmand mmChemical mmSensors
Chapter mm11. mmElectrophoresis
Chapter mm12. mmChromatography
Chapter mm13. mmMass mmSpectrometry
Chapter mm14. mmEnzyme mmand mmRate mmAnalyses
Chapter mm15. mmImmunochemical mmTechniques
Chapter mm16 mmAutomation
Chapter mm17. mmPoint-of-Care mmInstrumentation
III. m m Analytes
Chapter mm18. mmAmino mmAcids, mmPeptides, mmand mmProteins
Chapter mm19. mmSerum mmEnzymes
Chapter mm20. mmTumor mmMarkers mmand mmCancer mmGenes
Chapter mm21. mmKidney mmFunction mmTests mm— mmCreatinine, mmGFR, mmUrea, mmand mmUric mmAcid
Chapter mm22. mmCarbohydrates
Chapter mm23. mmLipids, mmLipoproteins, mmApolipoproteins, mmand mmOther mmCardiac mmRisk mmFactors
Chapter mm24. mmElectrolytes mmand mmBlood mmGases
Chapter mm25. mmHormones
Chapter mm26. m m Catecholamines mmand mmSerotonin
Chapter mm27. m m Vitamins, mmTrace mmElements, mmNutritional mmAssessment
Chapter mm28. mmHemoglobin, mmIron, mmand mmBilirubin
Chapter mm29. mmPorphyrins mmand mmPorphyrias
Chapter mm30. mmTherapeutic mmDrugs mmand mmTheir mmManagement
Chapter mm31. mmClinical mmToxicology
Chapter mm32. m m Toxic mmMetals
IV. m m Pathophysiology
Chapter mm33. mmDiabetes
,Chapter mm34. m m Cardiovascular mmDisease
Chapter mm35. mmKidney mmDisease
Chapter mm36. m m Physiology mmand mmDisorders mmof mmWater, mmElectrolyte, mmand mmAcid-Base
mmMetabolism
Chapter mm37. mm mmLiver mmDisease
Chapter mm38. m m Gastrointestinal mmand mmPancreatic mmDiseases
Chapter mm39. mm mmDisorders mmof mmBone mmand mmMineral mmMetabolism
Chapter mm40. mm mmDisorders mmof mmthe mmPituitary mmGland
Chapter mm41. m m Disorders mmof mmthe mmAdrenal mmCortex
Chapter mm42. m m Thyroid mmDisorders
Chapter mm43. m m Reproduction-Related mmDisorders
Chapter mm44. mm mmPregnancy mmand mmPrenatal mmTesting
Chapter mm45. m m Newborn mmScreening mmand mmInborn mmErrors mmof mmMetabolism
Chapter mm46. mmPharmacogenetics
V. m m Molecular mmDiagnostics
Chapter mm47. mmPrinciples mmof mmMolecular mmBiology
Chapter mm48. mmNucleic mmAcid mmTechniques mmand mmApplications
Chapter mm49. mmGenomes mmand mmNucleic mmAcid mmAlterations
, Chapter mm01: mmClinical mmChemistry, mmMolecular mmDiagnostics, mmand mmLaboratory
mmMedicine mmTestmBank
m
MULTIPLE mmCHOICE
1. An mmindividual mmworking mmin mma mmclinical mmchemistry mmlaboratory mmis mmmarried mmto mma mmsales
mmrepresentative mmwho mmworks mmfor mma mmcompany mmthat mmsells mmchemistry mmlaboratory
mmsupplies. mmWhen mmthe mmlaboratory mmmanager mmrequests mma mmlist mmof mmneeded mmsupplies,
mmcost mmof mmsupplies, mmand mmvendors, mmthis mmindividual mmonlym
mrecommends mmthe mmspouse’s
mmcompany mmas mmthe mmvendor. mmThis mmis mmconsidered mmto mmbe mma(n):
a. accounting mmissue.
b. possible mmconflict mmof mminterest.
c. maintenance mmof mmconfidentiality mmissue.
d. problem mmwith mmresource mmallocation.
ANS: m m B
Concern mmhas mmbeen mmraised mmover mmthe mminterrelationships mmbetween mmpractitioners mmin mmthe
mmmedical mmfieldm and mmcommercial mmsuppliers mmof mmdrugs, mmdevices, mmequipment, mmetc., mmto
m
mmthe mmmedical mm profession.
Similarly, mmrelationships mmhave mmbeen mmscrutinized mmbetween mmclinical mmlaboratorians mmand
mmmanufacturers mmand mmproviders mmof mmdiagnostic mmequipment mmand mmsupplies. mmThese
mmconcerns mmled mmthe mmNational mmInstitutes mmof mmHealth mm(NIH) mmin mm1995 mmto mmrequire
mmofficial mminstitutional mmreview mmof mmfinancial mmdisclosure mmby mmresearchers mmand
mmmanagement mmof mmsituations mmin mmwhich mmdisclosure mmindicates mmpotentialm conflicts mmof
m
mminterest.
DIF: 1 REF: mm mm mmPage mm4-5 OBJ: m m 6 mm| mm7
2. A mmpatient mmvisits mmher mmphysician mmstating mmthat mmher mmprescribed mmpainkiller mmis mmnot
mmworking mmto mmreduce mmthe mmpain mmfollowing mmher mmrecent mmsurgery. mmA mmfriend mmof mmthe
mmpatient mmclaims mmthat mmthe mmsame mmpainkillermm―worked mmwonders‖ mmto mmreduce mmher mmpain
mmafter mmthe mmsame mmsurgery. mmThe mmphysician mmstates mmthat mmthe mmdifference mmin mmthe mmeffect
mmof mm the mmdrug mmmight mmbe mmcaused mmby , mmwhich mmis mmstudied mmin
mmpharmacogenetics.
a. epidemiology
b. an mminherited mmdisease
c. a mmconflict mmof mminterest
d. a mmgenetic mmvariation mmin mmdrug-metabolizing mmenzymes
ANS: m m D
Pharmacogenetics mmis mmthe mmstudy mmof mmthe mmgenetic mmvariation mmof mmdrug
mmmetabolism mmbetweenm individuals.
m
DIF: 1 REF: mm mm mmPage mm3 OBJ: m m 1
3. John mmworks mmin mma mmmolecular mmdiagnostics mmlaboratory mmand mmreceives mma mmblood
mmsample mmthat mmhas mmthe mmname mmof mma mmclose mmfriend mmprinted mmon mmthe mmbar-coded mmlabel.
mmThe mmgenetic mmtest mmthat mmis mmordered mmon mmthemmfriend’s mmsample mmwould mmprovide
mmdiagnostic mminformation mmabout mma mmdisorder mmthat mmhas mma mmpoor mmprognosis, mmand mmthe
mmtest mmis mmusually mmperformed mmby mmJohn. mmHe mmasks mma mmfellow mmemployee mmto mmanalyze
m
mthe mmsample mmfor mmhim mmand mmnot mmdivulge mmthe mmresults. mmThis mmethical mmissue mmconcerns:
a. confidentiality mmof mmpatient mmgenetic mmand mmmedical mminformation.
b. a mmconflict mmof mminterest.
c. resource mmallocation.
d. diagnostic mmaccuracy.