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APEA 3P Actual Exam Test Bank 2026 – Complete Practice Questions with Verified Answers

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This document contains a comprehensive test bank for the APEA 3P Actual Exam 2026. It includes practice questions and verified answers covering advanced pathophysiology, advanced pharmacology, and advanced physical assessment concepts. The material is structured to support exam preparation and reinforce clinical reasoning for nurse practitioner students.

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APEA 3P EXAM TEST BANK | 2026
UPDATE VERSION


A 67-year-old woman with a history of A-fib and an ejection fraction of 48% has
had normal digoxin levels. Which can cause a decrease of digoxin level?
• a) Decreased creatinine clearance
• b) Weight loss
• c) Increased exercise
• d) Regular use of antacids
d) Regular use of antacids
• Rationale: Antacids can decrease digoxin absorption, lowering serum levels.




A pediatric patient has areas of scaling on the scalp with round patches of
alopecia. This clinical finding is consistent with:
• a) Tinea capitis
• b) Seborrheic dermatitis
• c) Trichotillomania
• d) Alopecia areata
a) Tinea capitis
• Rationale: Tinea capitis presents with scaly patches and alopecia on the scalp.

,Which finding below would be unusual in a patient with diabetic retinopathy?


a) Papilledema


b) Dot and blot hemorrhages


c) Microaneurysms


d) Cotton wool spots


a) Papilledema


Rationale: Papilledema is not a feature of diabetic retinopathy; it is more
associated with increased intracranial pressure.




Why would a combined hormonal contraceptive be contraindicated in a 36-year-
old patient with a past medical history of type 2 diabetes, obesity, chronic
smoking, and a sedentary lifestyle?
• a) She is obese
• b) She has type 2 diabetes mellitus
• c) Her age and tobacco use
• d) She leads a sedentary lifestyle
c) Her age and tobacco use
• Rationale: Combined oral contraceptives are contraindicated in women older
than 35 who smoke due to an increased risk of cardiovascular events.

,5-alpha reductase inhibitors work to improve symptoms of benign prostatic
hyperplasia by:
• a) Decreasing the size of the prostate
• b) Increasing blood flow to the prostate
• c) Relaxing smooth muscle in the bladder neck
• d) Relaxing smooth muscle in the prostate capsule
a) Decreasing the size of the prostate
• Rationale: 5-alpha reductase inhibitors reduce dihydrotestosterone levels,
leading to prostate shrinkage.




Which medication is indicated for patients with generalized anxiety disorder?
• a) Buspirone (Buspar)
• b) Citalopram (Celexa)
• c) Imipramine (Tofranil)
• d) Bupropion HCL (Wellbutrin)
a) Buspirone (Buspar)
• Rationale: Buspirone is specifically indicated for generalized anxiety disorder,
while the other medications are primarily antidepressants.

, Pregnant women are evaluated for syphilis with serology testing because:
• a) Syphilis during pregnancy predisposes the fetus to spontaneously abort or the
newborn to have congenital syphilis
• b) Hormonal changes associated with pregnancy may trigger activation of latent
syphilis
• c) Syphilis may be passed to the fetus beginning in the third trimester
• d) Untreated syphilis can cause neonatal respiratory distress
a) Syphilis during pregnancy predisposes the fetus to spontaneously abort or the
newborn to have congenital syphilis
• Rationale: Syphilis can result in severe complications for both the mother and
fetus, including congenital syphilis and spontaneous abortion.




Which lesion is dark, raised, and asymmetric with an irregular border?
• a) Nevus
• b) Actinic keratosis
• c) Keratoacanthoma
• d) Melanoma
d) Melanoma
• Rationale: Melanomas are dark, asymmetric lesions with irregular borders and
require immediate evaluation.




A 32-year-old woman presents with dull puffiness of the eyes and pronounced
non-pitting periorbital edema. This finding is suggestive of which condition?
• a) Nephrotic syndrome

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