NUR 1141: Introduction to Pharmacotherapeutics (AS)
Pharmacology: Endocrine, Antibiotics, and Cardiovascular
Drugs Overview
Acyclovir Correct Answers A guanosine analogue.
Adverse effects (Acyclovir) Correct Answers Renal dysfunction
(IV), headache, GI upset, local irritation.
Adverse effects (Amphotericin B) Correct Answers Infusion
reactions (fever/chills), nephrotoxicity (hypokalemia,
hypomagnesemia), anemia.
Adverse effects (Hormonal Contraceptives) Correct Answers
Nausea, breast tenderness, breakthrough bleeding, increased risk
of VTE with estrogen (esp. smokers >35), possible slight HTN
risk.
Adverse effects (Isoniazid) Correct Answers Hepatotoxicity,
peripheral neuropathy (pyridoxine prevents), drug interactions
via CYP inhibition.
Adverse effects (Tetracyclines) Correct Answers Teeth
discoloration and bone growth inhibition — avoid in pregnancy
and children <8, GI upset.
Adverse effects Correct Answers Hyperglycemia,
immunosuppression, osteoporosis, weight gain, Cushingoid
features, adrenal suppression, mood changes, peptic ulcers.
,Adverse effects of Alendronate Correct Answers
Esophagitis/erosion, osteonecrosis of the jaw (rare), atypical
femoral fractures (long-term).
Adverse effects of Aspirin Correct Answers GI
bleeding/ulceration, tinnitus (salicylism), bronchospasm in
aspirin-sensitive asthmatics.
Adverse effects of Celecoxib Correct Answers Edema, HTN,
increased CV risk, possible renal impairment.
Adverse effects of cephalosporins Correct Answers
Hypersensitivity, GI upset, C. difficile; some (cefotetan) cause
disulfiram-like reaction with alcohol.
Adverse effects of Finasteride Correct Answers Decreased
libido, erectile dysfunction, decreased ejaculate volume,
possible breast tenderness/enlargement.
Adverse effects of Fluconazole Correct Answers Hepatotoxicity
(rare), GI upset, QT prolongation (rare).
Adverse effects of Fludrocortisone Correct Answers
Hypertension, edema, hypokalemia, weight gain, heart failure
exacerbation.
Adverse effects of Glipizide Correct Answers Hypoglycemia,
weight gain, GI upset, possible dermatologic reactions.
, Adverse effects of Ibuprofen Correct Answers GI
bleeding/ulceration, renal impairment, exacerbation of heart
failure, increased CV risk with long term use.
Adverse effects of Indinavir Correct Answers Nephrolithiasis
(crystalluria), hyperglycemia, lipodystrophy, hyperlipidemia, GI
upset.
Adverse effects of Insulin Correct Answers Hypoglycemia,
weight gain, injection site reactions, lipodystrophy.
Adverse effects of Levothyroxine Correct Answers Symptoms
of hyperthyroidism if over-replaced (tachycardia, weight loss,
tremor, heat intolerance).
Adverse effects of macrolides Correct Answers GI upset, QT
prolongation (esp. azithro/clarithro), cholestatic jaundice (rare).
Adverse effects of Metformin Correct Answers GI upset
(nausea, diarrhea), metallic taste, rare lactic acidosis (in renal
failure/sepsis/hypoxia).
Adverse effects of Metronidazole Correct Answers GI upset,
metallic taste, neuropathy with prolonged use, disulfiram-like
reaction.
Adverse effects of ovulation induction Correct Answers Hot
flashes, ovarian enlargement, visual disturbances, multiple
pregnancy risk.
Pharmacology: Endocrine, Antibiotics, and Cardiovascular
Drugs Overview
Acyclovir Correct Answers A guanosine analogue.
Adverse effects (Acyclovir) Correct Answers Renal dysfunction
(IV), headache, GI upset, local irritation.
Adverse effects (Amphotericin B) Correct Answers Infusion
reactions (fever/chills), nephrotoxicity (hypokalemia,
hypomagnesemia), anemia.
Adverse effects (Hormonal Contraceptives) Correct Answers
Nausea, breast tenderness, breakthrough bleeding, increased risk
of VTE with estrogen (esp. smokers >35), possible slight HTN
risk.
Adverse effects (Isoniazid) Correct Answers Hepatotoxicity,
peripheral neuropathy (pyridoxine prevents), drug interactions
via CYP inhibition.
Adverse effects (Tetracyclines) Correct Answers Teeth
discoloration and bone growth inhibition — avoid in pregnancy
and children <8, GI upset.
Adverse effects Correct Answers Hyperglycemia,
immunosuppression, osteoporosis, weight gain, Cushingoid
features, adrenal suppression, mood changes, peptic ulcers.
,Adverse effects of Alendronate Correct Answers
Esophagitis/erosion, osteonecrosis of the jaw (rare), atypical
femoral fractures (long-term).
Adverse effects of Aspirin Correct Answers GI
bleeding/ulceration, tinnitus (salicylism), bronchospasm in
aspirin-sensitive asthmatics.
Adverse effects of Celecoxib Correct Answers Edema, HTN,
increased CV risk, possible renal impairment.
Adverse effects of cephalosporins Correct Answers
Hypersensitivity, GI upset, C. difficile; some (cefotetan) cause
disulfiram-like reaction with alcohol.
Adverse effects of Finasteride Correct Answers Decreased
libido, erectile dysfunction, decreased ejaculate volume,
possible breast tenderness/enlargement.
Adverse effects of Fluconazole Correct Answers Hepatotoxicity
(rare), GI upset, QT prolongation (rare).
Adverse effects of Fludrocortisone Correct Answers
Hypertension, edema, hypokalemia, weight gain, heart failure
exacerbation.
Adverse effects of Glipizide Correct Answers Hypoglycemia,
weight gain, GI upset, possible dermatologic reactions.
, Adverse effects of Ibuprofen Correct Answers GI
bleeding/ulceration, renal impairment, exacerbation of heart
failure, increased CV risk with long term use.
Adverse effects of Indinavir Correct Answers Nephrolithiasis
(crystalluria), hyperglycemia, lipodystrophy, hyperlipidemia, GI
upset.
Adverse effects of Insulin Correct Answers Hypoglycemia,
weight gain, injection site reactions, lipodystrophy.
Adverse effects of Levothyroxine Correct Answers Symptoms
of hyperthyroidism if over-replaced (tachycardia, weight loss,
tremor, heat intolerance).
Adverse effects of macrolides Correct Answers GI upset, QT
prolongation (esp. azithro/clarithro), cholestatic jaundice (rare).
Adverse effects of Metformin Correct Answers GI upset
(nausea, diarrhea), metallic taste, rare lactic acidosis (in renal
failure/sepsis/hypoxia).
Adverse effects of Metronidazole Correct Answers GI upset,
metallic taste, neuropathy with prolonged use, disulfiram-like
reaction.
Adverse effects of ovulation induction Correct Answers Hot
flashes, ovarian enlargement, visual disturbances, multiple
pregnancy risk.
