The first cell at the site of an infec on is a(n) -correct answersneutrophil
A pa ern recogni on receptor is (are) -correct answerstoll-like receptor
A secondary lymphoid organ is (are) -correct answersSALT
The innate immune system used -correct answersPRR to recognize PAMP
The phagocy c cell that does not arrive first at the site of a chronic infec on is the -correct
answersmacrophage
The two different cells needed to produce a monoclonal an body are -correct answersA
myeloma cell that does not survive in the media used a er fusion and a spleen cell from an
immunized animal
Immunoglobulin diversity is produced in three stages. Which stage(s) is (are) accomplished a er
interac on with an gen -correct answersClonal dele on of self-reac ve B cells and soma c
muta on and affinity matura on
, If a par cular IgG molecule and IgM molecule have the same affinity, which would have a higher
avidity -correct answersIgM
The area which soma c muta on occurs and increased affinity of an body develops is the -
correct answerslymph node
In the original experiment which determined the structure of immunoglobulins, it was broken
into heavy and light chains using -correct answersurea and mercaptoethanol
To get an body diversity to the level that is needed, -correct answersrecombina on events
occur, slight changes in the junc onal region during recombina on can occur, and soma c
muta on can occur
The an body molecule that has 10 binding sites but because of steric hinderance o en binds
only five an gen molecules is -correct answersIgM
The paratope that is seen as an an gen is called an -correct answersidotype
A spleen cell and a myeloma cell are used to produce a monoclonal an body. How do they help
produce a monoclonal an body -correct answersThe myeloma cell and the spleen cell are fused
to become one cell, a hybridoma
Immunoglobulin diversity and T cell receptor diversity both involve random recombina onal
events to create diversity -correct answersA er an gen exposure, B cells have soma c
muta onal events to improve affinity, but T cells do not
Monoclonal an bodies are produced by cells that are the hybrids of -correct answersspleen
cells and myeloma cells