COMPREHENSIVE PRACTICE EXAM 2026: HIGH-
YIELD QUESTIONS & RATIONALES
A 32 year old man has acute bronchitis. He is a non smoker and is otherwise healthy. How
should he be managed?
A. Treat symptoms only
B. Prescribe a macrolide antibiotic.
C. Prescribe an an antitussive.
D. Prescribe an antibiotic and antitussive. - ---correct answer ---A. Treat symptoms
only
An 84 year old male has acute bronchitis. Which of the following tests would you perform as the
Nurse Practitioner?
A. Sputum culture
B. Chest X-ray
C. Chest CT
D. Chest MRI - ---correct answer ---B. Chest X-ray
A 58 year old male has acute bronchitis. He is a heavy smoker, but is otherwise healthy. What is
the most likely etiology?
A. Viral infection
B. S. pneumoniae
C. B. Pertussis
D. Haemophilus influenzae - ---correct answer ---D. Haemophilus influenzae
A 76 year old man has acute productive cough, fever 100-101 F for the past 3-4 days. He is a non
smoker and is otherwise healthy. Which likely diagnosis should be included in your differential?
,A. Acute bronchitis
B. Pneumonitis
C. Pneumonia
D. COPD
E. Bronchiectasis
F. Pertussis - ---correct answer ---C. Pneumonia
Which of the following warrant a chest x-ray when an acute cough is present?
A. Temp 100.4
B. HR 86
C. Rales, consolidation
D. >65 years of age
E. RR 26 - ---correct answer ---A. C. E.
Abnormal vital signs (increased RR or HR, temp >100.4)
Rales, consolidation
>75 years of age with cough
A 76 year old male has a chest x-ray that shows infiltrates. Which of the following medication is
first-line treatment?
A. Amoxicillin 1 gram TID
B. Doxycycline 100 mg BID
C. Azithromycin 500 mg on first day, then 250 mg daily
D. Clarithromycin 500 mg BID - ---correct answer ---A. Amoxicillin 1 gram TID
A 76 year old male with a he of COPD, diabetes mellitus, and alcoholism has a chest x-ray that
shows infiltrates. Which of the following medications is first line treatment?
A. Amoxicillin
B. Levofloxacin
, C. Azithromycin
D. Doxycycline - ---correct answer ---B. Levofloxacin
A 76 year old male with a he of COPD, diabetes mellitus, and alcoholism has a chest x-ray that
shows infiltrates. Which of the following is the most likely pathogen?
A. H. flu
B. S. Pneumoniae
C. B. Pertussis
D. Viral infection - ---correct answer ---A. H. flu.
A 56 year old male has suspected COPD. Which of the following symptoms are indicative of
COPD?
A. Progressive dyspnea
B. Acute cough
C. Sputum productive over the past 2 months
D. FEV1/FVC ratio >0.70
E. Alpha-1 antitrypsin deficiency - ---correct answer ---A. C. E.
Chronic cough >8 weeks and FEV1/FVC ration <0.70.
A 56 year old male has been diagnosed with COPD. Which of the follow medications is
considered first-line?
A. SABAs (albuterol)
B. LABAs (salmeterol)
C. Inhaled anticholinergics (ipratropium)
D. LAAC (aclindinium) - ---correct answer ---A. SABAs (albuterol) is first-line
Which of the following diagnoses decrease Hgb over time?
A. COPD Stage 3