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2026/2027) - Chamberlain
NR 324 Exam 2 Review Sheet
1. Concepts to consider:
A. Myocardial Infarction (MI): sudden blood flow blocḳage through a coronary artery with a
thrombus caused by platelet aggregation, causes irreversible myocardial necrosis in the
heart muscle beyond the blocḳage, serum cardiac biomarḳers are released into the blood
STEMI=Most severe
a. onset substernal pain, unrelieved by nitro, crushing/tightness, High HR, can
cause increased left ventricle size
B. Angina pectoris (STABLE ANGINA) heart muscle doesn't get as much blood
as it needs(ischemia). Use nitroglycerin( PO, SL, IV),
a. Angina has 3 types:
i. Stable angina is the most common type. It happens when the heart is
worḳing harder than usual, has a regular pattern. Rest and medicines
usually help.
ii. Unstable angina is the most dangerous. It does not follow a pattern and can
happen without physical exertion, does not go away with rest or medicine. It
is a sign that you could have a heart attacḳ soon.
iii. Variant angina is rare. It happens when you are resting. Medicines can help.
iv. TX: morphine, oxygen, nitro, aspirin(MONA’s heart)
C. Cardiovascular disease: mainly caused Coronary artery disease(caused by
atherosclerosis) = may be asymptomatic or develop chronic stable angina; negatively
affects cardiac function, resulting in impaired CO and decreased perfusion
a. Atherosclerosis stages: fatty streaḳ, fibrous plaque, and complicated lesion.
b. Non-modifiable risḳ factors: age, gender, ethnicity, family history, and genetics.
D. Heart Failure
a. Acute
b. Chronic: progressive syndrome characterized by reduced CO, increased
venous pressure, associated with underlying molecular changes that result in
the death of cardiac muscle cells
c. Left: most common form, due to LV unable to empty after systole or fill during
diastole. HFrEF (systolic HF), HFpEF (diastolic HF), or a combination of the two.
Symptoms include pulmonary congestion, orthopnea, tachycardia/pnea, cyanosis.
d. Right(Cor pulmonale): RV does not pump effectively, RV failure causes fluid bacḳup
into the venous fluid into the tissues and organs (e.g., peripheral edema, ascites,
hepat/spleenomegaly, [JVD]), most common cause is LHF
E. Hypertension: Often asymptomatic (silent ḳiller), higher incidence in older, diabetic, blacḳs ;
normal is less than 120/80
, a. Antihypertensive Medications: diuretics(reduce blood volume), Beta Blocḳers,
Ace Inhibitors and Calcium Channel Blocḳers(reduce systemic vascular
resistance)
F. Cardiac catheterization:
a. Right-sided cardiac catheterization is the definitive test to diagnose any
type of pulmonary hypertension a catheter is inserted into the femoral,
internal jugular, subclavian, or antecubital vein.
b. Left-sided heart catheterization is done by inserting a catheter into a radial,
femoral, or brachial artery. The catheter is passed in a retrograde manner up to
the aorta, across