ONCC PRACTICE TESTS OCN CARE
CONTINUUM FINAL STUDY GUIDE 2026
SOLVED QUESTIONS FULLY CORRECT
⫸ Alkylating agents exert their effects by:
binding to DNA strands, preventing DNA replication and cell division.
causing the release of toxic free radicals inside the cell, triggering cell
apoptosis.
attaching to CD52 on the surface of B and T cells, resulting in antibody-
dependent lysis.
disrupting folate-dependent metabolic processes essential for cell
replication. Answer: binding to DNA strands, preventing DNA
replication and cell division.
Answer: Alkalyting agents break the DNA helix strand and interfere
with DNA replication.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27(t).
⫸ The nurse preparing to instill intravesical mitomycin should wear
which of the following pieces of personal protective equipment?
,A plastic face shield
A pair of shoe covers
A front-closing laboratory gown
One pair of powdered nitrile gloves Answer: A plastic face shield
Answer: A plastic face shield should be used when splashing of
hazardous drugs is possible. Intravesical administration carries a risk of
splashing.
Reference: Polovich, M. (2017). Safe handling of hazardous drugs (3rd
ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27.
⫸ Adjuvant therapy for breast cancer is administered:
after primary therapy to increase the chance of long-term, disease-free
survival.
before primary therapy to shrink a tumor that is inoperable in its current
state.
at any time during therapy to cure the patient and kill cancer cells.
to locally treat cancer with minimal harm to normal cells. Answer: after
primary therapy to increase the chance of long-term, disease-free
survival.
Answer: The goal of adjuvant therapy is to target minimal, residual
disease for patients at high risk of developing metastasis.
, Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 5.
⫸ Hormone therapy is effective for which two types of cancer?
Breast and prostate
Sarcoma and small cell lung
Lymphoma and gallbladder
Liver and chronic myeloid leukemia Answer: Breast and prostate
Answer: Hormone therapy has been successfully used to treat breast and
prostate cancers.
Reference: Eggert, J. (Ed.). (2017). Cancer basics (2nd ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 259.
⫸ A 25-year-old patient is being treated with temozolomide. The patient
is instructed to:
take the medication at bedtime on an empty stomach.
divide the medication doses over 24 hours.
consume a magnesium supplement with the medication.
CONTINUUM FINAL STUDY GUIDE 2026
SOLVED QUESTIONS FULLY CORRECT
⫸ Alkylating agents exert their effects by:
binding to DNA strands, preventing DNA replication and cell division.
causing the release of toxic free radicals inside the cell, triggering cell
apoptosis.
attaching to CD52 on the surface of B and T cells, resulting in antibody-
dependent lysis.
disrupting folate-dependent metabolic processes essential for cell
replication. Answer: binding to DNA strands, preventing DNA
replication and cell division.
Answer: Alkalyting agents break the DNA helix strand and interfere
with DNA replication.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27(t).
⫸ The nurse preparing to instill intravesical mitomycin should wear
which of the following pieces of personal protective equipment?
,A plastic face shield
A pair of shoe covers
A front-closing laboratory gown
One pair of powdered nitrile gloves Answer: A plastic face shield
Answer: A plastic face shield should be used when splashing of
hazardous drugs is possible. Intravesical administration carries a risk of
splashing.
Reference: Polovich, M. (2017). Safe handling of hazardous drugs (3rd
ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27.
⫸ Adjuvant therapy for breast cancer is administered:
after primary therapy to increase the chance of long-term, disease-free
survival.
before primary therapy to shrink a tumor that is inoperable in its current
state.
at any time during therapy to cure the patient and kill cancer cells.
to locally treat cancer with minimal harm to normal cells. Answer: after
primary therapy to increase the chance of long-term, disease-free
survival.
Answer: The goal of adjuvant therapy is to target minimal, residual
disease for patients at high risk of developing metastasis.
, Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014).
Chemotherapy and biotherapy guidelines and recommendations for
practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 5.
⫸ Hormone therapy is effective for which two types of cancer?
Breast and prostate
Sarcoma and small cell lung
Lymphoma and gallbladder
Liver and chronic myeloid leukemia Answer: Breast and prostate
Answer: Hormone therapy has been successfully used to treat breast and
prostate cancers.
Reference: Eggert, J. (Ed.). (2017). Cancer basics (2nd ed.). Pittsburgh,
PA: Oncology Nursing Society, p. 259.
⫸ A 25-year-old patient is being treated with temozolomide. The patient
is instructed to:
take the medication at bedtime on an empty stomach.
divide the medication doses over 24 hours.
consume a magnesium supplement with the medication.
