GASTROINTESTINAL SYSTEM DRUGS EXAM
2026-2027 QUESTIONS AND CORRECT ANSWERS
GRADED A+
A nurse is caring for a client with cancer regularly administered opioids. The client
tells the nurse they need a laxative. What would be the best laxative to address
opioid induced constipation?
A. Bisacodyl
B. Mineral oil
C. Inulin
D. Docusate sodium
A. Bisacodyl
What is the benefit of adding proton pump inhibitors (PPIs) to the treatment regime
treating an H. pylori bacterial infection?
A. decreases pepsin production
B. protects ulcer craters
C .assists in eliminating the bacteria
D. decreases production of gastric secretions
D. decreases production of gastric secretions
What is the mechanism of action of hydroxyzine (Vistaril), an antihistamine, that
enables it to have antiemetic effects?
,A. Binds to histamine receptors in the respiratory tract
B. Blocks dopamine receptors in the brain
C. Blocks the action of acetylcholine in the brain
D. Relaxes skeletal muscle
C. Blocks the action of acetylcholine in the brain
Metoclopramide is classified as a nonphenothiazine antiemetic.
False
True
True
Pancreatic enzymes are required for absorption of carbohydrates, protein, and fat.
Replacement therapy is used when clients are in deficiency states. What conditions
create a deficiency state for pancreatic enzymes?
A. All choices are correct
B. Cystic fibrosis
C. Pancreatic obstruction
D. Chronic pancreatitis
All choices are correct
What is the removal of possibly toxic substances triggered by the medulla called?
A. Elimination
B. Vomiting
,C. Swallowing
D. Peristalsis
B. Vomiting
A nurse instructs a client taking an antidiarrheal agent to stop the drug and call the
health care provider if the client does not experience relief within which time
frame?
48 hours
72 hours
36 hours
24 hours
48 hours
While reviewing the medication history of a client newly prescribed omeprazole,
the nurse sees that the client is also taking warfarin. What potential interaction
should the nurse account for when developing the plan of care for this client?
A. hemorrhage
B. venous thromboembolism
C. rebound gastroesophageal reflux disease (GERD)
D. fluid volume excess
A. hemorrhage
, A client has sought care because their diarrhea has not resolved, despite taking
over-the-counter loperamide 12 mg/day for the past 2 days. In addition to referring
the client to their health care provider, the nurse will provide which instruction?
A. Supplement the loperamide with psyllium.
B. Increase the dose to 16 mg/day until seeing the health care provider.
C. Stop taking the medication.
D. Reduce fluid intake to 1 L/day until the diarrhea resolves.
C. Stop taking the medication.
Carter, age 2, is diagnosed with cystic fibrosis; the physician places him on
pancrelipase. What would be the most appropriate diagnosis for Carter related to
his medication regimen?
A. Risk for injury related to the side effects of the drug therapy
B. Alteration in comfort related to the drug therapy and the adverse effect of a
headache
C. Imbalanced nutrition: less than body requirements, related to impaired digestion
secondary to insufficient pancreatic enzymes
D. Alterations in elimination related to the disease process
C. Imbalanced nutrition: less than body requirements, related to impaired digestion
secondary to insufficient pancreatic enzymes
When considering the tendency of antiemetic agents to cross the placenta, which
assessment question should the nurse initially ask every childbearing aged woman
before initiating the therapy?
A. "Do you plan to get pregnant anytime soon?"
B. "Have you ever been pregnant?"
2026-2027 QUESTIONS AND CORRECT ANSWERS
GRADED A+
A nurse is caring for a client with cancer regularly administered opioids. The client
tells the nurse they need a laxative. What would be the best laxative to address
opioid induced constipation?
A. Bisacodyl
B. Mineral oil
C. Inulin
D. Docusate sodium
A. Bisacodyl
What is the benefit of adding proton pump inhibitors (PPIs) to the treatment regime
treating an H. pylori bacterial infection?
A. decreases pepsin production
B. protects ulcer craters
C .assists in eliminating the bacteria
D. decreases production of gastric secretions
D. decreases production of gastric secretions
What is the mechanism of action of hydroxyzine (Vistaril), an antihistamine, that
enables it to have antiemetic effects?
,A. Binds to histamine receptors in the respiratory tract
B. Blocks dopamine receptors in the brain
C. Blocks the action of acetylcholine in the brain
D. Relaxes skeletal muscle
C. Blocks the action of acetylcholine in the brain
Metoclopramide is classified as a nonphenothiazine antiemetic.
False
True
True
Pancreatic enzymes are required for absorption of carbohydrates, protein, and fat.
Replacement therapy is used when clients are in deficiency states. What conditions
create a deficiency state for pancreatic enzymes?
A. All choices are correct
B. Cystic fibrosis
C. Pancreatic obstruction
D. Chronic pancreatitis
All choices are correct
What is the removal of possibly toxic substances triggered by the medulla called?
A. Elimination
B. Vomiting
,C. Swallowing
D. Peristalsis
B. Vomiting
A nurse instructs a client taking an antidiarrheal agent to stop the drug and call the
health care provider if the client does not experience relief within which time
frame?
48 hours
72 hours
36 hours
24 hours
48 hours
While reviewing the medication history of a client newly prescribed omeprazole,
the nurse sees that the client is also taking warfarin. What potential interaction
should the nurse account for when developing the plan of care for this client?
A. hemorrhage
B. venous thromboembolism
C. rebound gastroesophageal reflux disease (GERD)
D. fluid volume excess
A. hemorrhage
, A client has sought care because their diarrhea has not resolved, despite taking
over-the-counter loperamide 12 mg/day for the past 2 days. In addition to referring
the client to their health care provider, the nurse will provide which instruction?
A. Supplement the loperamide with psyllium.
B. Increase the dose to 16 mg/day until seeing the health care provider.
C. Stop taking the medication.
D. Reduce fluid intake to 1 L/day until the diarrhea resolves.
C. Stop taking the medication.
Carter, age 2, is diagnosed with cystic fibrosis; the physician places him on
pancrelipase. What would be the most appropriate diagnosis for Carter related to
his medication regimen?
A. Risk for injury related to the side effects of the drug therapy
B. Alteration in comfort related to the drug therapy and the adverse effect of a
headache
C. Imbalanced nutrition: less than body requirements, related to impaired digestion
secondary to insufficient pancreatic enzymes
D. Alterations in elimination related to the disease process
C. Imbalanced nutrition: less than body requirements, related to impaired digestion
secondary to insufficient pancreatic enzymes
When considering the tendency of antiemetic agents to cross the placenta, which
assessment question should the nurse initially ask every childbearing aged woman
before initiating the therapy?
A. "Do you plan to get pregnant anytime soon?"
B. "Have you ever been pregnant?"
