Lehne's Pharmacology for Nursing Care -
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
UNIT I: INTRODUCTION
Chapter 1 – Orientation to Pharmacology
Lehne’s Pharmacology for Nursing Care, 12th Edition
20 High-Yield NCLEX-Style MCQs
1. A nurse explains that pharmacology primarily involves which
of the following?
A. The study of herbal supplements only
B. The study of drugs and their effects on living systems
,C. The study of disease pathology
D. The study of surgical interventions
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their
interactions with living systems, including mechanisms, effects,
and clinical use.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology.
2. Which statement best describes pharmacodynamics?
A. Study of drug absorption and excretion
B. Study of drug concentration in plasma
C. Study of biochemical and physiologic effects of drugs
D. Study of drug cost-effectiveness
Correct Answer: C
Rationale: Pharmacodynamics examines what drugs do to the
body, including mechanisms of action and physiologic
responses.
Citation: Lehne’s, 12th ed., Ch. 1 – Orientation to
Pharmacology.
3. Which process is part of pharmacokinetics?
A. Receptor binding
B. Drug metabolism
,C. Therapeutic effect
D. Drug-receptor specificity
Correct Answer: B
Rationale: Pharmacokinetics describes drug movement through
the body: absorption, distribution, metabolism, and excretion
(ADME).
Citation: Lehne’s, 12th ed., Ch. 1 – Orientation to
Pharmacology.
4. A drug that produces the same response as a naturally
occurring substance is classified as a(n):
A. Antagonist
B. Partial agonist
C. Agonist
D. Enzyme inhibitor
Correct Answer: C
Rationale: An agonist activates receptors to produce a response
similar to endogenous compounds.
Citation: Lehne’s, 12th ed., Ch. 1.
5. A drug that blocks receptor activation without activating the
receptor is a(n):
A. Agonist
B. Antagonist
, C. Potentiator
D. Synergist
Correct Answer: B
Rationale: Antagonists bind to receptors but prevent activation,
blocking the effects of agonists.
Citation: Lehne’s, 12th ed., Ch. 1.
6. Which term describes the highest effect a drug can produce?
A. Potency
B. Efficacy
C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the maximal therapeutic response a
drug can achieve.
Citation: Lehne’s, 12th ed., Ch. 1.
7. A nurse notes Drug A requires a lower dose than Drug B to
achieve the same effect. Drug A is more:
A. Effective
B. Toxic
C. Potent
D. Selective
Correct Answer: C
Rationale: Potency refers to the amount of drug needed to
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
UNIT I: INTRODUCTION
Chapter 1 – Orientation to Pharmacology
Lehne’s Pharmacology for Nursing Care, 12th Edition
20 High-Yield NCLEX-Style MCQs
1. A nurse explains that pharmacology primarily involves which
of the following?
A. The study of herbal supplements only
B. The study of drugs and their effects on living systems
,C. The study of disease pathology
D. The study of surgical interventions
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their
interactions with living systems, including mechanisms, effects,
and clinical use.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology.
2. Which statement best describes pharmacodynamics?
A. Study of drug absorption and excretion
B. Study of drug concentration in plasma
C. Study of biochemical and physiologic effects of drugs
D. Study of drug cost-effectiveness
Correct Answer: C
Rationale: Pharmacodynamics examines what drugs do to the
body, including mechanisms of action and physiologic
responses.
Citation: Lehne’s, 12th ed., Ch. 1 – Orientation to
Pharmacology.
3. Which process is part of pharmacokinetics?
A. Receptor binding
B. Drug metabolism
,C. Therapeutic effect
D. Drug-receptor specificity
Correct Answer: B
Rationale: Pharmacokinetics describes drug movement through
the body: absorption, distribution, metabolism, and excretion
(ADME).
Citation: Lehne’s, 12th ed., Ch. 1 – Orientation to
Pharmacology.
4. A drug that produces the same response as a naturally
occurring substance is classified as a(n):
A. Antagonist
B. Partial agonist
C. Agonist
D. Enzyme inhibitor
Correct Answer: C
Rationale: An agonist activates receptors to produce a response
similar to endogenous compounds.
Citation: Lehne’s, 12th ed., Ch. 1.
5. A drug that blocks receptor activation without activating the
receptor is a(n):
A. Agonist
B. Antagonist
, C. Potentiator
D. Synergist
Correct Answer: B
Rationale: Antagonists bind to receptors but prevent activation,
blocking the effects of agonists.
Citation: Lehne’s, 12th ed., Ch. 1.
6. Which term describes the highest effect a drug can produce?
A. Potency
B. Efficacy
C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the maximal therapeutic response a
drug can achieve.
Citation: Lehne’s, 12th ed., Ch. 1.
7. A nurse notes Drug A requires a lower dose than Drug B to
achieve the same effect. Drug A is more:
A. Effective
B. Toxic
C. Potent
D. Selective
Correct Answer: C
Rationale: Potency refers to the amount of drug needed to
