NUR242: Maternal Newborn Nursing- Exam 1, Part 2
Study online at https://quizlet.com/_by3b9n
1. Drug Therapy During Breast-Feeding: Drugs can be excreted in breast milk, and effects can occur
in the infant
Pharm Chapter 3
2. Drug therapy during pregnancy:: -drug cross the placenta by diffusion
- Factors affecting safety: Drug properties, Fetal gestational age, Maternal factors
-FDA has implemented pregnancy safety categories
Pharm Chapter 3
3. Pregnancy Safety Categories: - A: Studies indicate no risk to the human fetus
- B: Studies indicate no risk to the animal fetus
- C: Adverse effects reported in the animal fetus; information for humans is not available
- D: Possible fetal risk; must weigh potential benefits against risks
- X: Positive fetal risk; not normally used during pregnancy (Do no give to pregnant mother)
Pharm Chapter 3
4. Classification of young patients:: - younger than 38 weeks gestation: premature or pre-term infant
- younger than 1 month: neonate or newborn infant
- 1month~ 1 year: infant
- 1 year ~ 12 years: child
Pharm Chapter 3
5. Neonatal and Pediatric Considerations: Pharmacokinetics: Absorption
- Gastric pH less acidic until 1-2 years old
- Absorption is a lot easier when you are more basic than acidic
- Gastric emptying slowed
- Intramuscular absorption faster and irregular
Distribution
- Greater total body water means lower fat content
- decreased level of protein binding
- immature blood-brain barrier- more drugs enter the brain
Metabolism
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, NUR242: Maternal Newborn Nursing- Exam 1, Part 2
Study online at https://quizlet.com/_by3b9n
- Liver immature; does not produce enough microsomal enzymes
- other children may have increased metabolism, requiring higher doses than infants
Excretion
- Kidney is immature which slows Glomerular filtration rate
- decreased perfusion rate of kidney may reduce excretion of drugs
Pharm Chapter 3
6. Pharm Chapter 3 (Pharm lifespan considerations) main concept:: Babies absorb
faster and babies excrete slower
Pharm Chapter 34 Women's health Drugs
7. Main female sex hormone: Estrogenic, progesterone, FSH (follicle-stimulating hormone), LH (luteiniz-
ing hormone)
Pharm Chapter 34 Women's health Drugs
8. Estrogen: endogenous (made in the body)
-development and maintenance of female reproductive system
- responsible for secondary sexual characteristics or bodily features that appear in puberty
- Estrone: weak or minor estrogen, helps with sexual development
- Estriol: a weak or minor estrogen: Has to be pregnant to use estriol, helps grow uterus to maintain pregnancy
Pharm Chapter 34 Women's health Drugs
9. Exogenous (outside of the body; given to) Estrogenic Drugs: Synthetic: - Steroidal
Conjugated estrogens (mixed drugs)
- Nonsteroidal
Pharm Chapter 34 Women's health Drugs
10. Estrogenic drugs: - Conjugates estrogens (Premarin)
- Depo-Provera (birth control shot) used to treat uterine bleeding, secondary amenorrhea, endometrial cancer
Pharm Chapter 34 Women's health Drugs
11. Estrogen: indications: - Osteoporosis (treatment and prophylaxis)
- uterine bleeding
- breast or prostate cancer
Pharm Chapter 34 Women's health Drugs
12. Progestins: - levonorgestrel (Plan B)
Pharm Chapter 34 Women's health Drugs
2/7
Study online at https://quizlet.com/_by3b9n
1. Drug Therapy During Breast-Feeding: Drugs can be excreted in breast milk, and effects can occur
in the infant
Pharm Chapter 3
2. Drug therapy during pregnancy:: -drug cross the placenta by diffusion
- Factors affecting safety: Drug properties, Fetal gestational age, Maternal factors
-FDA has implemented pregnancy safety categories
Pharm Chapter 3
3. Pregnancy Safety Categories: - A: Studies indicate no risk to the human fetus
- B: Studies indicate no risk to the animal fetus
- C: Adverse effects reported in the animal fetus; information for humans is not available
- D: Possible fetal risk; must weigh potential benefits against risks
- X: Positive fetal risk; not normally used during pregnancy (Do no give to pregnant mother)
Pharm Chapter 3
4. Classification of young patients:: - younger than 38 weeks gestation: premature or pre-term infant
- younger than 1 month: neonate or newborn infant
- 1month~ 1 year: infant
- 1 year ~ 12 years: child
Pharm Chapter 3
5. Neonatal and Pediatric Considerations: Pharmacokinetics: Absorption
- Gastric pH less acidic until 1-2 years old
- Absorption is a lot easier when you are more basic than acidic
- Gastric emptying slowed
- Intramuscular absorption faster and irregular
Distribution
- Greater total body water means lower fat content
- decreased level of protein binding
- immature blood-brain barrier- more drugs enter the brain
Metabolism
1/7
, NUR242: Maternal Newborn Nursing- Exam 1, Part 2
Study online at https://quizlet.com/_by3b9n
- Liver immature; does not produce enough microsomal enzymes
- other children may have increased metabolism, requiring higher doses than infants
Excretion
- Kidney is immature which slows Glomerular filtration rate
- decreased perfusion rate of kidney may reduce excretion of drugs
Pharm Chapter 3
6. Pharm Chapter 3 (Pharm lifespan considerations) main concept:: Babies absorb
faster and babies excrete slower
Pharm Chapter 34 Women's health Drugs
7. Main female sex hormone: Estrogenic, progesterone, FSH (follicle-stimulating hormone), LH (luteiniz-
ing hormone)
Pharm Chapter 34 Women's health Drugs
8. Estrogen: endogenous (made in the body)
-development and maintenance of female reproductive system
- responsible for secondary sexual characteristics or bodily features that appear in puberty
- Estrone: weak or minor estrogen, helps with sexual development
- Estriol: a weak or minor estrogen: Has to be pregnant to use estriol, helps grow uterus to maintain pregnancy
Pharm Chapter 34 Women's health Drugs
9. Exogenous (outside of the body; given to) Estrogenic Drugs: Synthetic: - Steroidal
Conjugated estrogens (mixed drugs)
- Nonsteroidal
Pharm Chapter 34 Women's health Drugs
10. Estrogenic drugs: - Conjugates estrogens (Premarin)
- Depo-Provera (birth control shot) used to treat uterine bleeding, secondary amenorrhea, endometrial cancer
Pharm Chapter 34 Women's health Drugs
11. Estrogen: indications: - Osteoporosis (treatment and prophylaxis)
- uterine bleeding
- breast or prostate cancer
Pharm Chapter 34 Women's health Drugs
12. Progestins: - levonorgestrel (Plan B)
Pharm Chapter 34 Women's health Drugs
2/7
