TEST BANK
Tietz Fundamentals Of
CLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS
7th Edition By Carl A. Burtis
TEST BANK w q
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 7th Edition Test Bank
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Table of contents: wq wq
I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis wq wq
Chapter 12. Chromatography wq wq
Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation wq wq
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes wq wq wq
Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates wq wq
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones wq wq
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals wq w q wq
IV. Pathophysiology
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Chapter 33. Diabetes wq wq
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Tietz Fundamentals of Clinical Chemistry and MolecularDiagnostics, 7e Burtis Test Bank
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Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory MedicineTest Bank
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MULTIPLE CHOICE wq
1. An individual working in a clinical chemistry laboratory is married to a sales representative w
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ho works for a company that sells chemistry laboratory supplies. When the laboratory manage
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r requests a list of needed supplies, cost of supplies, and vendors, this individual only recomme
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nds the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. wq
b. possible conflict of interest. wq wq wq
c. maintenance of confidentiality issue. wq wq wq
d. problem with resource allocation. wq wq wq
ANS: B wq
Concern has been raised over the interrelationships between practitioners in the medical field and
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commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
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and providers of diagnostic equipment and supplies. These concerns led the National Institutes
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of Health (NIH) in 1995 to require official institutional review of financial disclosure by researc
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hers and management of situations in which disclosure indicates potential conflicts of interest.
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DIF: 1 REF: w q Page 4-5 wq OBJ: 6 | 7 w q wq wq
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce t
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he pain following her recent surgery. A friend of the patient claims that the same painkiller “w
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orked wonders” to reduce her pain after the same surgery. The physician states that the differ
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ence in the effect of the drug might be caused by
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, which is studied in pharmacoge wq wq wq wq wq
netics.
a. epidemiology
b. an inherited disease wq wq
c. a conflict of interest wq wq wq
d. a genetic variation in drug-metabolizing enzymes
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ANS: D wq
Pharmacogenetics is the study of the genetic variation of drug metabolism between individua wq wq wq wq wq wq wq wq wq wq wq wq
ls.
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3. John works in a molecular diagnostics laboratory and receives a blood sample that has the na
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me of a close friend printed on the bar-
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coded label. The genetic test that is ordered on the friend’s sample would provide diagnostic i
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nformation about a disorder that has a poor prognosis, and the test is usually performed by Jo
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hn. He asks a fellow employee to analyze the sample for him and not divulge the results. Thi
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s ethical issue concerns:
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a. confidentiality of patient genetic and medical information. wq wq wq wq wq wq
b. a conflict of interest. wq wq wq
c. resource allocation. wq
d. diagnostic accuracy. wq
Tietz Fundamentals Of
CLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS
7th Edition By Carl A. Burtis
TEST BANK w q
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 7th Edition Test Bank
wq wq wq wq wq wq wq wq
wq
wq wq
Table of contents: wq wq
I. Principles Of Laboratory Medicine
wq wq wq wq
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
wq wq wq wq wq wq wq wq
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
wq wq wq wq wq wq wq wq wq wq wq
Chapter 3. Clinical Evaluation of Methods
wq wq wq wq wq
Chapter 4. Evidence-Based Laboratory Medicine
wq wq wq wq
Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
wq wq wq wq wq wq wq wq
Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
wq wq wq wq wq wq wq wq
Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis wq wq
Chapter 12. Chromatography wq wq
Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation wq wq
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes wq wq wq
Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates wq wq
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones wq wq
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals wq w q wq
IV. Pathophysiology
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Chapter 33. Diabetes wq wq
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Tietz Fundamentals of Clinical Chemistry and MolecularDiagnostics, 7e Burtis Test Bank
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Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory MedicineTest Bank
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MULTIPLE CHOICE wq
1. An individual working in a clinical chemistry laboratory is married to a sales representative w
wq wq wq wq wq wq wq wq wq wq wq wq wq wq
ho works for a company that sells chemistry laboratory supplies. When the laboratory manage
wq wq wq wq wq wq wq wq wq wq wq wq wq
r requests a list of needed supplies, cost of supplies, and vendors, this individual only recomme
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
nds the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. wq
b. possible conflict of interest. wq wq wq
c. maintenance of confidentiality issue. wq wq wq
d. problem with resource allocation. wq wq wq
ANS: B wq
Concern has been raised over the interrelationships between practitioners in the medical field and
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commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
wq wq wq wq wq wq wq wq wq
and providers of diagnostic equipment and supplies. These concerns led the National Institutes
wq wq wq wq wq wq wq wq wq wq wq wq wq wq
of Health (NIH) in 1995 to require official institutional review of financial disclosure by researc
wq wq wq wq wq wq wq wq wq wq wq wq wq wq
hers and management of situations in which disclosure indicates potential conflicts of interest.
wq wq wq wq wq wq wq wq wq wq wq wq
DIF: 1 REF: w q Page 4-5 wq OBJ: 6 | 7 w q wq wq
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce t
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
he pain following her recent surgery. A friend of the patient claims that the same painkiller “w
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
orked wonders” to reduce her pain after the same surgery. The physician states that the differ
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
ence in the effect of the drug might be caused by
wq wq wq wq wq wq wq wq wq wq
, which is studied in pharmacoge wq wq wq wq wq
netics.
a. epidemiology
b. an inherited disease wq wq
c. a conflict of interest wq wq wq
d. a genetic variation in drug-metabolizing enzymes
wq wq wq wq wq
ANS: D wq
Pharmacogenetics is the study of the genetic variation of drug metabolism between individua wq wq wq wq wq wq wq wq wq wq wq wq
ls.
DIF: 1 REF: Page 3 w q w q wq OBJ: 1 wq
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the na
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
me of a close friend printed on the bar-
wq wq wq wq wq wq wq wq
coded label. The genetic test that is ordered on the friend’s sample would provide diagnostic i
wq wq wq wq wq wq wq wq wq wq wq wq wq wq wq
nformation about a disorder that has a poor prognosis, and the test is usually performed by Jo
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hn. He asks a fellow employee to analyze the sample for him and not divulge the results. Thi
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s ethical issue concerns:
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a. confidentiality of patient genetic and medical information. wq wq wq wq wq wq
b. a conflict of interest. wq wq wq
c. resource allocation. wq
d. diagnostic accuracy. wq
