1
NR 566 Midterm Exam Study Guide
Advanced Pharmacology for Care of the
Family Questions and Answers A+
When is Lorcaserin contraindicated? <<Answer>> CrCl <30
-Not approved in children
Lorcaserin drug interactions <<Answer>> -MAOI inhibitors,
SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning <<Answer>>
increased risk for suicidal ideation and suicide attempts in
children, adolescents, and young adults
Do not take Naltrexone and Bupropion within weeks of
taking a . <<Answer>> - two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can
reduce effects of what? <<Answer>> opioids
Naltrexone and Bupropion contraindications <<Answer>> HTN,
seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA <<Answer>> -promotes weight loss by slowing
gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to
increase
bp
m <<Answer>> 10-20
,2
-monitor for tachycardia
When taking Liraglutide, monitor for in patients with
diabetes <<Answer>> hypoglycemia
Baseline labs for Liraglutide <<Answer>> lipids, CMP, HgA1C q 6
months, triglycerides
Liraglutide black box warning <<Answer>> associated with a risk
for thyroid C-cell tumors based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia
syndrome type 2 (MEN 2) or personal/family history of medullary
thyroid carcinoma
Those trying to LOSE weight should exercise at least
min/week or
more <<Answer>> 150
What BMI is bariatric surgery considered? <<Answer>> 35 or
more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to
medication and lifestyle therapy? % whereas > % is
exceptional <<Answer>> 10-15%
,3
> 15%
Most weight loss occurs during the first months of treatment
<<Answer>> 6
T or F: Dosage adjustments are not indicated for orlistat,
diethylpropion, and phentermine in the elderly <<Answer>> T
Stage 0: <<Answer>> BMI ≥ 25 = lifestyle therapy -> consider
drug therapy if lifestyle therapy is ineffective to meet goals
Stage 1: <<Answer>> BMI of 25-26 = lifestyle therapy -> consider
drug therapy if lifestyle therapy is ineffective to meet goals
BMI ≥ 27 = lifestyle therapy, consider drug therapy
Stage 2: <<Answer>> BMI 25-26 = lifestyle therapy -> consider
drug therapy if ineffective to meet goals
BMI 27-34 = lifestyle therapy, drug therapy
BMI ≥ 35 = lifestyle therapy + drug therapy + consider bariatric
surgery
Inhibitors (decrease medication metabolism)
<<Answer>> Valproate Isoniazid
Sulfonamide
Amiodarone
Chloramphe
nicol
Ketoconazol
e Grapefruit
juice
Quinidine
"VISA credit card debt inhibits spending on designers like CK to
look GQ"
Cimetidine
Ciprofloxaci
, 4
n
Erythromyci
n INH
Inducers (increase medication metabolism) <<Answer>>
Carbamazepine Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbit
al
Sulfonylurea
s
"CRAP GPS"
NR 566 Midterm Exam Study Guide
Advanced Pharmacology for Care of the
Family Questions and Answers A+
When is Lorcaserin contraindicated? <<Answer>> CrCl <30
-Not approved in children
Lorcaserin drug interactions <<Answer>> -MAOI inhibitors,
SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning <<Answer>>
increased risk for suicidal ideation and suicide attempts in
children, adolescents, and young adults
Do not take Naltrexone and Bupropion within weeks of
taking a . <<Answer>> - two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can
reduce effects of what? <<Answer>> opioids
Naltrexone and Bupropion contraindications <<Answer>> HTN,
seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA <<Answer>> -promotes weight loss by slowing
gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to
increase
bp
m <<Answer>> 10-20
,2
-monitor for tachycardia
When taking Liraglutide, monitor for in patients with
diabetes <<Answer>> hypoglycemia
Baseline labs for Liraglutide <<Answer>> lipids, CMP, HgA1C q 6
months, triglycerides
Liraglutide black box warning <<Answer>> associated with a risk
for thyroid C-cell tumors based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia
syndrome type 2 (MEN 2) or personal/family history of medullary
thyroid carcinoma
Those trying to LOSE weight should exercise at least
min/week or
more <<Answer>> 150
What BMI is bariatric surgery considered? <<Answer>> 35 or
more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to
medication and lifestyle therapy? % whereas > % is
exceptional <<Answer>> 10-15%
,3
> 15%
Most weight loss occurs during the first months of treatment
<<Answer>> 6
T or F: Dosage adjustments are not indicated for orlistat,
diethylpropion, and phentermine in the elderly <<Answer>> T
Stage 0: <<Answer>> BMI ≥ 25 = lifestyle therapy -> consider
drug therapy if lifestyle therapy is ineffective to meet goals
Stage 1: <<Answer>> BMI of 25-26 = lifestyle therapy -> consider
drug therapy if lifestyle therapy is ineffective to meet goals
BMI ≥ 27 = lifestyle therapy, consider drug therapy
Stage 2: <<Answer>> BMI 25-26 = lifestyle therapy -> consider
drug therapy if ineffective to meet goals
BMI 27-34 = lifestyle therapy, drug therapy
BMI ≥ 35 = lifestyle therapy + drug therapy + consider bariatric
surgery
Inhibitors (decrease medication metabolism)
<<Answer>> Valproate Isoniazid
Sulfonamide
Amiodarone
Chloramphe
nicol
Ketoconazol
e Grapefruit
juice
Quinidine
"VISA credit card debt inhibits spending on designers like CK to
look GQ"
Cimetidine
Ciprofloxaci
, 4
n
Erythromyci
n INH
Inducers (increase medication metabolism) <<Answer>>
Carbamazepine Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbit
al
Sulfonylurea
s
"CRAP GPS"
