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NURS 5315/ NURS5315 Final Exam – Advanced Pathophysiology | UTA (Latest 2026 Update) 100% Verified Questions & Answers | Grade A

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NURS 5315/ NURS5315 Final Exam – Advanced Pathophysiology | UTA (Latest 2026 Update) 100% Verified Questions & Answers | Grade A QUESTION The nurse practitioner notes that a patient has a pH of 7. 25 and a bicarbonate of 10. Which of following laboratory tests is most important for the nurse practitioner to review? sodium magnesium potassium creatinine Answer: The pH and bicarbonate in this question are consistent with a metabolic acidosis. The nurse practitioner should review the potassium level. Hyperkalemia is a common electrolyte imbalance seen in a metabolic acidosis. During a metabolic acidosis, hydrogen (a positive ion) shifts into the intracellular space. In order to maintain the ionic balance, potassium (a positive ion) shifts to the extracellular space and results in a hyperkalemia. None of the other labs are affected by a metabolic acidosis. QUESTION A patient is noted to have a high anion gap metabolic acidosis. Which of the following is the most likely etiology of the acidosis? CO2 retention Ethanol ingestion Vomiting Diuretic use Answer: The elevated anion gap in the setting of a metabolic acidosis is consistent with ethanol ingestion. CO2 retention results in an altered mental status and a respiratory acidosis not a metabolic acidosis. Diuretic use and vomiting may cause a metabolic alkalosis. QUESTION A child is diagnosed with osteogenic sarcoma. From which tissue did the cancer originate? A connective B epithelial C liver D nerve tissue Answer: A. Cancers arising from connective tissue, usually have the suffix "sarcoma". Epithelial cancers typically have the prefix "adeno". The liver is considered epithelial tissue. Cancerous which originate from nervous tissue have the suffix "balstoma". QUESTION Upon examining a paraplegic patient, the nurse practitioner notes that the patient's lower extremities are thin and wasted. This is an example of which cellular adaptation pattern? A. Atrophy B Hypertrophy C hyperplasia D dysplasia Answer: QUESTION Upon examining a paraplegic patient the nurse practitioner notes that the patient's lower extremities are thin and wasted. This is an example of which cellular adaptation pattern? a. Atrophy b. Hypertrophy c. Hyperplasia d. Dysplasia Answer: ANS: A The patient in this scenario has experienced muscle wasting (atrophy) secondary to the loss of use of their lower extremities. Hypertrophy is an enlargement of the cells in a tissue secondary to the increased demands on the cells. This type of response occurs in weightlifters or in the heart from increased blood pressure. Hyperplasia is the increased in the number of cells in a tissue. The cell size and organization are completely normal; however, the number of cells present in the tissue is more than normal. This is seen in benign prostatic hyperplasia. Dysplasia is an erratic arrangement in the cell's organization, sizes, and shape in a tissue. This is a pre-cancerous state seen in cervical dysplasia. QUESTION A patient with a long-standing history of GERD is at greater risk of which cellular adaptation pattern? a. Esophageal hypertrophy b. Esophageal metaplasia c. Esophageal atrophy d. Esophageal dysplasia Answer: ANS: B Long-standing GERD predisposed the esophageal cells to undergo a metaplasia. In esophageal metaplasia the normal esophageal squamous epithelial cells are replaced by intestinal-like columnar cells under the influence of the refluxed gastric acid. The columnar cells are better equipped to handle the refluxed hydrochloric acid. It is pre-cancerous condition. None of the other adaptation patterns are pertinent.

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NURSl 5315/l NURS5315l Finall Examl –l
Advancedl Pathophysiologyl |l UTAl (Latestl
2026l Update)l 100%l Verifiedl Questionsl &l
Answersl |l Gradel A

Q:l Thel nursel practitionerl notesl thatl al patientl hasl al pHl ofl 7.l 25l andl al bicarbonatel
ofl 10.l Whichl ofl followingl laboratoryl testsl isl mostl importantl forl thel nursel practitionerl
tol review?

sodium
magnesium
potassium
creatinine

Answer:
Thel pHl andl bicarbonatel inl thisl questionl arel consistentl withl al metabolicl acidosis.l Thel
nursel practitionerl shouldl reviewl thel potassiuml level.l Hyperkalemial isl al commonl
electrolytel imbalancel seenl inl al metabolicl acidosis.l Duringl al metabolicl acidosis,l
hydrogenl (al positivel ion)l shiftsl intol thel intracellularl space.l Inl orderl tol maintainl thel
ionicl balance,l potassiuml (al positivel ion)l shiftsl tol thel extracellularl spacel andl resultsl inl
al hyperkalemia.l Nonel ofl thel otherl labsl arel affectedl byl al metabolicl acidosis.l



Q:l Al patientl isl notedl tol havel al highl anionl gapl metabolicl acidosis.l Whichl ofl thel
followingl isl thel mostl likelyl etiologyl ofl thel acidosis?

CO2l retention
Ethanoll ingestion
Vomiting
Diureticl use

Answer:

,Thel elevatedl anionl gapl inl thel settingl ofl al metabolicl acidosisl isl consistentl withl ethanoll
ingestion.l CO2l retentionl resultsl inl anl alteredl mentall statusl andl al respiratoryl acidosisl
notl al metabolicl acidosis.l Diureticl usel andl vomitingl mayl causel al metabolicl alkalosis.l



Q:l Al childl isl diagnosedl withl osteogenicl sarcoma.l Froml whichl tissuel didl thel cancerl
originate?

Al connective
Bl epitheliall
Cl liverl
Dl nervel tissue

Answer:
A.l Cancersl arisingl froml connectivel tissue,l usuallyl havel thel suffixl "sarcoma".l Epitheliall
cancersl typicallyl havel thel prefixl "adeno".l Thel liverl isl consideredl epitheliall tissue.l
Cancerousl whichl originatel froml nervousl tissuel havel thel suffixl "balstoma".l



Q:l Uponl examiningl al paraplegicl patient,l thel nursel practitionerl notesl thatl thel patient'sl
lowerl extremitiesl arel thinl andl wasted.l Thisl isl anl examplel ofl whichl cellularl adaptationl
pattern?

A.l Atrophy
Bl Hypertrophy
Cl hyperplasial
Dl dysplasia

Answer:




Q:l Uponl examiningl al paraplegicl patientl thel nursel practitionerl notesl thatl thel patient'sl
lowerl extremitiesl arel thinl andl wasted.l Thisl isl anl examplel ofl whichl cellularl adaptationl
pattern?
a.l Atrophy
b.l Hypertrophy
c.l Hyperplasia
d.l Dysplasia

, Answer:
ANS:l A

Thel patientl inl thisl scenariol hasl experiencedl musclel wastingl (atrophy)l secondaryl tol thel
lossl ofl usel ofl theirl lowerl extremities.l Hypertrophyl isl anl enlargementl ofl thel cellsl inl al
tissuel secondaryl tol thel increasedl demandsl onl thel cells.l Thisl typel ofl responsel occursl inl
weightliftersl orl inl thel heartl froml increasedl bloodl pressure.l Hyperplasial isl thel increasedl
inl thel numberl ofl cellsl inl al tissue.l Thel celll sizel andl organizationl arel completelyl
normal;l however,l thel numberl ofl cellsl presentl inl thel tissuel isl morel thanl normal.l Thisl
isl seenl inl benignl prostaticl hyperplasia.l Dysplasial isl anl erraticl arrangementl inl thel cell'sl
organization,l sizes,l andl shapel inl al tissue.l Thisl isl al pre-cancerousl statel seenl inl cervicall
dysplasia.l



Q:l Al patientl withl al long-standingl historyl ofl GERDl isl atl greaterl riskl ofl whichl
cellularl adaptationl pattern?
a.l Esophageall hypertrophy
b.l Esophageall metaplasia
c.l Esophageall atrophy
d.l Esophageall dysplasia

Answer:
ANS:l B

Long-standingl GERDl predisposedl thel esophageall cellsl tol undergol al metaplasia.l Inl
esophageall metaplasial thel normall esophageall squamousl epitheliall cellsl arel replacedl byl
intestinal-likel columnarl cellsl underl thel influencel ofl thel refluxedl gastricl acid.l Thel
columnarl cellsl arel betterl equippedl tol handlel thel refluxedl hydrochloricl acid.l Itl isl pre-
cancerousl condition.l Nonel ofl thel otherl adaptationl patternsl arel pertinent.l



Q:l Al 50-year-oldl malel isl diagnosedl withl primaryl lungl adenocarcinoma.l Froml whichl
tissuel didl thisl cancerl originate?
a.l Glandularl epithelial
b.l Deepl Connectivel Tissue
c.l Superficiall connective
d.l Musclel tissue

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