NBME BIOCHEMISTRY SHELF EXAM NEWEST
2026 QUESTIONS and CORRECT DETAILED
ANSWERS ALREADY GRADED A+
What steroid can be used to treat beta-blocker overdose? - CORRECT
ANSWER-glucagon
Which form of aldolase is liver-specific? - CORRECT ANSWER-B
triose phosphate isomerase - CORRECT ANSWER-G3P <-> DHAP; DHAP -
component of glycerol phosphate shuttle
What TCA step makes GTP? - CORRECT ANSWER-succinate thiokinase
What TCA step makes FADH? - CORRECT ANSWER-succinate dehydrogenase
What is the only membrane-bound enzyme in TCA? - CORRECT ANSWER-
succinate dehydrogenase
What characterizes succinate? - CORRECT ANSWER-dicarboxylic acid
,What neurotransmitter stimulates release of epinephrine from adrenal medulla? -
CORRECT ANSWER-acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What
is another assoc symptom? - CORRECT ANSWER-metanephrine; assoc with
HBP
What does acetazolamide (carbonic anhydrase ib) treat? - CORRECT ANSWER-
glaucoma, epilepsy, altitude sickness, congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - CORRECT ANSWER-pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - CORRECT ANSWER-Glu
HA protein of influenza binds to - CORRECT ANSWER-cytokine receptors
What is a reducing-sugar test? - CORRECT ANSWER-Tests for aldo-keto sugars
, What is omeprazole? - CORRECT ANSWER-proton pump ib
Name some GAG's. - CORRECT ANSWER-heparin sulfate, chondroitin sulfate,
What type of reaction is glucuronidation? - CORRECT ANSWER-oxidation
In Marfan's syndrome, what part of fibrillin's protein structure is affected? -
CORRECT ANSWER-primary structure
What are the symptoms of Huntington's disease? - CORRECT ANSWER-anxiety,
uncontrollable mvmts, slurring of speech, difficulty focusing or concentrating;
caused by triple repeat expansion
What is Chediak-Higashi syndrome? - CORRECT ANSWER-phagocyte deficiency
-> hypergammaglobulinemia, significant neutropenia,
In exposure to carbon monoxide or cyanide, which way does the ox sat curve
shift? - CORRECT ANSWER-to the L; increased affinity at low pO_2
What is pralidoxime chloride? - CORRECT ANSWER-reactivate
acetylcholinesterase
2026 QUESTIONS and CORRECT DETAILED
ANSWERS ALREADY GRADED A+
What steroid can be used to treat beta-blocker overdose? - CORRECT
ANSWER-glucagon
Which form of aldolase is liver-specific? - CORRECT ANSWER-B
triose phosphate isomerase - CORRECT ANSWER-G3P <-> DHAP; DHAP -
component of glycerol phosphate shuttle
What TCA step makes GTP? - CORRECT ANSWER-succinate thiokinase
What TCA step makes FADH? - CORRECT ANSWER-succinate dehydrogenase
What is the only membrane-bound enzyme in TCA? - CORRECT ANSWER-
succinate dehydrogenase
What characterizes succinate? - CORRECT ANSWER-dicarboxylic acid
,What neurotransmitter stimulates release of epinephrine from adrenal medulla? -
CORRECT ANSWER-acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What
is another assoc symptom? - CORRECT ANSWER-metanephrine; assoc with
HBP
What does acetazolamide (carbonic anhydrase ib) treat? - CORRECT ANSWER-
glaucoma, epilepsy, altitude sickness, congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - CORRECT ANSWER-pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - CORRECT ANSWER-Glu
HA protein of influenza binds to - CORRECT ANSWER-cytokine receptors
What is a reducing-sugar test? - CORRECT ANSWER-Tests for aldo-keto sugars
, What is omeprazole? - CORRECT ANSWER-proton pump ib
Name some GAG's. - CORRECT ANSWER-heparin sulfate, chondroitin sulfate,
What type of reaction is glucuronidation? - CORRECT ANSWER-oxidation
In Marfan's syndrome, what part of fibrillin's protein structure is affected? -
CORRECT ANSWER-primary structure
What are the symptoms of Huntington's disease? - CORRECT ANSWER-anxiety,
uncontrollable mvmts, slurring of speech, difficulty focusing or concentrating;
caused by triple repeat expansion
What is Chediak-Higashi syndrome? - CORRECT ANSWER-phagocyte deficiency
-> hypergammaglobulinemia, significant neutropenia,
In exposure to carbon monoxide or cyanide, which way does the ox sat curve
shift? - CORRECT ANSWER-to the L; increased affinity at low pO_2
What is pralidoxime chloride? - CORRECT ANSWER-reactivate
acetylcholinesterase
