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CCRN ADULT EXAM PREP 2026 | 500+ VERIFIED Q&A | ICU NURSING MASTERY | NGN RATIONALES | GRADED A+

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Secure your CCRN certification with the most rigorous and up-to-date study resource for 2026. This guide features over 500+ verified questions and answers, specifically designed to mirror the latest AACN blueprint and "Next Generation" style rationales. Why buy this? The CCRN exam isn't just about clinical facts; it's about the AACN Synergy Model and your ability to apply clinical judgment under pressure. This mastery document bridges that gap by providing high-yield Q&A that covers the most heavily weighted domains, including Cardiovascular (17%) and Respiratory (15%) systems. Each question includes a detailed rationale that explains the "why" behind the correct answer, helping you master complex ICU scenarios like hemodynamic monitoring, multisystem failure, and ethical dilemmas in end-of-life care. With a historical first-time pass rate hovering around 72-81%, don't leave your success to chance. This guide is your "Graded A+" roadmap to passing the 150-question exam on your first attempt, saving you hundreds in retest fees. The content breakdown includes comprehensive sections on Clinical Judgment (Cardiovascular, Pulmonary, Neuro, Renal, GI/Heme/Endo, and Multisystem) and the crucial Professional Caring & Ethical Practice domain, ensuring 100% syllabus alignment for the 2026 testing cycle.

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CCRN ADULT EXAM PREP 2026 | 500+ VERIFIED Q&A |
ICU NURSING MASTERY | NGN RATIONALES
A patient who is 72 hours postoperative repair of a bowel obstruction suddenly

demonstrates shortness of breath and his respiratory rate increases from 22 to 45/min. His

SpO2 went from 95% to 88% acutely. An arterial blood gas sample obtained while the

patient is receiving oxygen via a nasal cannula at 6L/min reveals the following results:

pH 7.40

pCO2 27

pO2 50

A chest x-ray is obtained and a "ground-glass-like appearance" is reported. Auscultation of

the lungs reveals diffuse crackles that were not present previously.



Your patient just received 10 units of banked blood for a GI bleed. You know this will affect

the oxyhemoglobin dissociation curve by:



A. Shifting it to the right

B. Causing a plateau in the curve

C. Shifting it to the left

D. Causing no change in the curve

C. Shifting it to the left

A patient who is 72 hours postoperative repair of a bowel obstruction suddenly

demonstrates shortness of breath and his respiratory rate increases from 22 to 45/min. His

,2|Page


SpO2 went from 95% to 88% acutely. An arterial blood gas sample obtained while the

patient is receiving oxygen via a nasal cannula at 6L/min reveals the following results:

pH 7.40

pCO2 27

pO2 50

A chest x-ray is obtained and a "ground-glass-like appearance" is reported. Auscultation of

the lungs reveals diffuse crackles that were not present previously.



Your patient is currently on a ventilator with the following settings: AC, FiO2 100%, Rate

of 12, Tidal Volume 450, PEEP of 5. His arterial blood gas results are the following: pH

7.36, PaCO2 43, PaO2 56, HCO3 28. Which ventilator parameter do you anticipate

changing?



A. Decrease the FiO2

B. Increase the tidal volume

C. Increase the PEEP

D. Increase the rate

C. Increase the PEEP

ARDS is characterized by which of the following:



A. Refractory hypercarbia

B. Increase in surfactant

,3|Page


C. Increased lung compliance

D. Shunting

D. Shunting



Rationale: ARDS is characterized by refractory hypoxia, shunting, decreased lung compliance,

and decreased surfactant.

A 42 y/o woman with a 6 month history of worsening anxiety, heat intolerance, and weight

loss presents to the emergency department. Which of the following are indicators of

hyperthyroidism?



A. Constipation, lower body temperature, and edema

B. High T3 and T4 and low TSH.

C. Depression, dementia, and reflex changes

D. Low T3 and T4 and high TSH

B. High T3 and T4 and low TSH.



Rationale: Constipation, lower body temperature, edema, depression, dementia, reflex changes,

low T3, low T4, high TSH are all indicators of hypothyroidism.

An elderly man with Type 2 DM comes into the emergency department after spending all

day in the mall shopping with his wife. He tells you that his heart is racing and he is sweaty

and shaky. What is the best course of action for the nurse?

, 4|Page


A. Give the patient a candy bar and drink regular soda then check his BG.

B. Check his blood glucose level and obtain an ECG.

C. Check his blood glucose and inject NPH insulin if he's hyperglycemic.

D. Give the patient 4 glucose tablets and then check his blood glucose.

B. Check his blood glucose level and obtain an ECG.

Successful treatment of DKA revolves around:



A. Correction of orthostatic hypotension with electrolytes

B. Administration of fluids, electrolytes and insulin

C. Gradually decreasing a patient's excessive fluid volume from hyperosmolality

D. Administration of glucagon to elevate plasma blood levels

B. Administration of fluids, electrolytes and insulin

What is the Somogyi phenomenon generally attributed?



A. Prolonged hyperglycemia that has led to neurological damage and impaired

counterregulatory response

B. Cyclic rise in blood glucose associated with increased need for insulin

C. Nocturnal food ingestion

D. Counter-regulatory response to severe hypoglycemia

D. Counter-regulatory response to severe hypoglycemia

The serum potassium (K+) of a patient with DKA is 5.4 mEq/l. What changes would the

nurse expect to see on an EKG?

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