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PNLE Medical-Surgical Nursing Reviewer 2025/2026 – Advanced Adult Health Comprehensive Exam Prep | High-Yield Practice Questions with Verified Answers & Detailed Rationales | Philippine Nursing Licensure Examination (Board Exam) Success Guide

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This PNLE Medical-Surgical Nursing Reviewer 2025/2026 is a comprehensive, high-yield board exam preparation guide specifically designed for candidates preparing for the Philippine Nursing Licensure Examination administered by the Professional Regulation Commission. Structured around adult health nursing principles most frequently tested in previous board cycles, this reviewer features carefully developed multiple-choice practice questions with verified correct answers and in-depth rationales explaining both correct and incorrect options to strengthen clinical judgment and critical thinking skills. Core content areas include cardiovascular, respiratory, endocrine, renal, gastrointestinal, neurological, hematologic, and musculoskeletal disorders; fluid and electrolyte balance; emergency and critical care concepts; pharmacologic management; perioperative nursing; prioritization and delegation; and evidence-based interventions. Each section is strategically organized to simulate real board exam conditions while reinforcing time management, test-taking strategy, and safe patient-centered care decision-making. Updated for the 2025/2026 examination cycle, this guide transforms complex medical-surgical concepts into structured, exam-focused review material designed to increase retention, improve accuracy, and boost first-attempt board exam success rates. Ideal for graduating BSN students and repeat examinees aiming to maximize performance and achieve professional licensure with confidence.

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PNLE MEdicaL-SurgicaL NurSiNg rEviEwEr
2025/2026 – advaNcEd aduLt HEaLtH
coMPrEHENSivE ExaM PrEP | HigH-YiELd PracticE
QuEStioNS witH vErifiEd aNSwErS & dEtaiLEd
ratioNaLES | PHiLiPPiNE NurSiNg LicENSurE
ExaMiNatioN (Board ExaM) SuccESS guidE
Question 1

Which of the following is the priority assessment for a patient with suspected acute
pancreatitis?

A) Blood glucose levels
B) Abdominal pain
C) Serum amylase and lipase
D) Vital signs

Correct Option: C) Serum amylase and lipase

Rationale:
In suspected acute pancreatitis, measuring serum amylase and lipase levels is critical because
elevated levels confirm the diagnosis. While abdominal pain (Option B) and vital signs (Option
D) are important, the lab values provide definitive evidence of pancreatitis.


Question 2

A nurse is caring for a patient with chronic obstructive pulmonary disease (COPD). Which
of the following actions should the nurse prioritize?

A) Encourage deep breathing exercises
B) Administer bronchodilators as prescribed
C) Monitor oxygen saturation levels
D) Educate the patient on smoking cessation

Correct Option: B) Administer bronchodilators as prescribed

Rationale:
Administering bronchodilators is the priority to relieve airway obstruction in COPD. Oxygen
saturation monitoring (Option C) is essential, but pharmacological intervention is critical for
immediate relief.


Question 3

,In a patient diagnosed with heart failure, which of the following signs indicates worsening
fluid overload?

A) Weight loss
B) Decreased urinary output
C) Peripheral edema
D) Increased heart rate

Correct Option: C) Peripheral edema
Rationale:
Peripheral edema is a classic sign of fluid overload in patients with heart failure, indicating the
body is retaining excess fluid. While decreased urinary output (Option B) may also indicate
overload, visible edema is a more immediate concern.


Question 4

Which of the following medications is the most appropriate for a patient experiencing a
hypertensive crisis?

A) Furosemide
B) Lisinopril
C) Nitroglycerin
D) Metoprolol

Correct Option: C) Nitroglycerin

Rationale:
Nitroglycerin is effective for rapid reduction of blood pressure in a hypertensive crisis due to its
vasodilating properties. While other medications can be used, nitroglycerin provides the quickest
response.


Question 5

A nurse is monitoring a client following a total hip replacement. Which of the following
findings would be considered an early indication of a potential complication?

A) Mild pain at the surgical site
B) Increased blood pressure
C) Sudden onset of shortness of breath
D) Low-grade fever
Correct Option: C) Sudden onset of shortness of breath

,Rationale:
Sudden onset of shortness of breath could indicate a pulmonary embolism, a serious
complication following hip surgery that requires immediate attention. Other symptoms, while
potentially concerning, do not signal immediate life-threatening conditions.
Question 6

Which laboratory value is most indicative of kidney function?

A) Liver enzymes
B) Serum creatinine
C) Hemoglobin
D) Electrolytes

Correct Option: B) Serum creatinine

Rationale:
Serum creatinine is a primary indicator of kidney function. Elevated levels suggest impaired
kidney function, making it crucial for assessing renal health.



Question 7
What is the primary nursing intervention for a patient experiencing chest pain?

A) Administer oxygen
B) Obtain an ECG
C) Start an IV line
D) Provide reassurance

Correct Option: A) Administer oxygen

Rationale:
Administering oxygen is critical to ensure adequate tissue perfusion in a patient with chest pain,
particularly if myocardial ischemia is suspected.



Question 8

A patient with diabetes is experiencing diabetic ketoacidosis (DKA). What clinical
manifestation should the nurse expect?

A) Bradycardia
B) Polyuria
C) Decreased respiratory rate
D) Hypertension

, Correct Option: B) Polyuria

Rationale:
Polyuria is a common symptom of DKA due to osmotic diuresis caused by high glucose levels.
Other options do not typically correlate with DKA.



Question 9

For which of the following conditions is the use of beta-blockers contraindicated?

A) Hypertension
B) Asthma
C) Angina
D) Atrial fibrillation

Correct Option: B) Asthma

Rationale:
Beta-blockers can cause bronchoconstriction, making them contraindicated for patients with
asthma, where airway constriction is a primary concern.



Question 10

What is a common side effect of opioid analgesics that nurses should monitor?

A) Hypertension
B) Constipation
C) Tachycardia
D) Diarrhea
Correct Option: B) Constipation

Rationale:
Opioids frequently cause constipation due to decreased gastrointestinal motility. This side effect
requires proactive management in patients receiving these medications.


Question 11

A patient with liver cirrhosis is at risk for developing which of the following complications?

A) Hyperglycemia
B) Hepatic encephalopathy

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