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Samenvatting Overzicht Geneesmiddelen deel 1 (Behaald Resultaat: 18/20)

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Dit document bevat een overzicht van al de geneesmiddelen van deel 2 van Pieter-Jan Guns met uitgebreide uitleg

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Farmacologie
Geneesmiddelen Partim I

5 Hydroxytryptamine of serotonine

Klasse: neurotransmitter

Aangrijpingspunt (receptoren): de 7 serotonine receptoren

Effect:

1A receptor: inhibitie neuronen

1B receptor: Vasculaire vasoconstrictie

1D receptor: Cerebrale vasoconstrictie

2 receptor: aggregatie bloedplaatjes

3 receptor: braakreflex en nociceptie

4 receptor: GI motiliteit, peristaltiek, gastroprokinetisch en anti-emmetisch

Bijwerkingen: /

Gebruik/indicatie:/

Contra indicaties:/

Belangrijke extra info:/

Acetylcholine

Klasse: neurotransmitter

Aangrijpingspunt (receptoren): muscarine en nictoninerge receptoren

Effect:

- mAchR: Rest and Digest actie van het autonoom zenuwstelsel, zweetsecretie van het
sympathisch zenuwstelsel, vasodilatatie door NO vrijstelling.
- nAchR: ganglionaire synapsen, motorische eindplaat, productie adrenaline in de bijnier.

Bijwerkingen: braken, miose, lensaccommodatie, diarree, incontinentie, bradycardie, spasmen

Gebruik/indicatie: /

Contra indicaties: /

Belangrijke extra info: wordt geïnactiveerd door Ach esterase.




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