Neuropharmacology - Advanced
Pharm - NURS8024 - Exam 3
Questions And 100% Correct Answers
\.In Parkinson's disease the amount of __________ lost directly
correlates to severity of symptoms. - ANSWERS✔-Dopamine
\.The goal of treatment for Parkinson's disease is to CURE and REVERSE
degeneration. T / F - ANSWERS✔-False - Tx focus is on restoring balance
\.Sinamet (Levodopa & Carbidopa) MOA includes: - ANSWERS✔-Assist
in conversion of levodopa to dopamine in the basal nigra - Increase in
body's production of dopamine
\.How does Carbidopa help in Parkinson's disease? - ANSWERS✔-
Carbidopa enhances availability of levodopa to cross the BBB. Decrease
metabolism of levodopa in the GI system
\.An NP understand that treatment effectiveness _____________
between the 3rd and 5th year of Parkinson treatment using sinemet. -
ANSWERS✔-Decreases
,\.Important Pt Ed on Levodopa: - ANSWERS✔-Take on an Empty
Stomach
\.ADE with Levodopa include: - ANSWERS✔-CNS effects
(Visual/Auditory Hallucinations, AIM, depression, GI effects, Tachy,
Acute glaucoma
\.Amantadine is used to treat? - ANSWERS✔-MINOR Parkinsons
\.MOA for Amantadine includes: - ANSWERS✔-Enhances dopaminergic
neurotransmission, muscarininc blocking
\.An NP would be cautious in prescribing Amantadine for minor
Parkinson's in a patient with what dx? - ANSWERS✔-Seizure D/O & CHF
\.Name two dopamine receptor agonists: - ANSWERS✔-Ropinirole &
Pramipexole
\.Name the one anticholingeric for EPS / Parkinsons - ANSWERS✔-
Cogentin / Benzotropine
, \.ADE of dopamine receptor agonists include: - ANSWERS✔-GI, Postural
HYPO, Dyskinesias, confusion, delusions, hallucinations, IMPULSIVITY
\.Ropinirole and Pramipexole CAUSE: - ANSWERS✔-IMPULSIVITY
\.Cogentin / Benzotropine is an________________ drug - ANSWERS✔-
Anticholinergic
\.MAO-B Inbhitors - ANSWERS✔-Monamine Oxidase B Inhibitors
\.When prescribing MAO-B Inhibitors use CAUTION with what two
medications? - ANSWERS✔-Fluoxetine or Meperidine (Prozac or
Demerol)
\.MAO-B Inhibitors include: - ANSWERS✔-Selegiline (Eldepryl) &
Rasagiline (Azilect)
\.Use MAO-B Inhibitors _____________ and adjunct with __________. -
ANSWERS✔-Early ; Levodopa
\.COMT (Catehcol-O-Methyltransferase Inhibitors) - ANSWERS✔-Help
with uptake of Levodopa which increases dopamine in CNS
Pharm - NURS8024 - Exam 3
Questions And 100% Correct Answers
\.In Parkinson's disease the amount of __________ lost directly
correlates to severity of symptoms. - ANSWERS✔-Dopamine
\.The goal of treatment for Parkinson's disease is to CURE and REVERSE
degeneration. T / F - ANSWERS✔-False - Tx focus is on restoring balance
\.Sinamet (Levodopa & Carbidopa) MOA includes: - ANSWERS✔-Assist
in conversion of levodopa to dopamine in the basal nigra - Increase in
body's production of dopamine
\.How does Carbidopa help in Parkinson's disease? - ANSWERS✔-
Carbidopa enhances availability of levodopa to cross the BBB. Decrease
metabolism of levodopa in the GI system
\.An NP understand that treatment effectiveness _____________
between the 3rd and 5th year of Parkinson treatment using sinemet. -
ANSWERS✔-Decreases
,\.Important Pt Ed on Levodopa: - ANSWERS✔-Take on an Empty
Stomach
\.ADE with Levodopa include: - ANSWERS✔-CNS effects
(Visual/Auditory Hallucinations, AIM, depression, GI effects, Tachy,
Acute glaucoma
\.Amantadine is used to treat? - ANSWERS✔-MINOR Parkinsons
\.MOA for Amantadine includes: - ANSWERS✔-Enhances dopaminergic
neurotransmission, muscarininc blocking
\.An NP would be cautious in prescribing Amantadine for minor
Parkinson's in a patient with what dx? - ANSWERS✔-Seizure D/O & CHF
\.Name two dopamine receptor agonists: - ANSWERS✔-Ropinirole &
Pramipexole
\.Name the one anticholingeric for EPS / Parkinsons - ANSWERS✔-
Cogentin / Benzotropine
, \.ADE of dopamine receptor agonists include: - ANSWERS✔-GI, Postural
HYPO, Dyskinesias, confusion, delusions, hallucinations, IMPULSIVITY
\.Ropinirole and Pramipexole CAUSE: - ANSWERS✔-IMPULSIVITY
\.Cogentin / Benzotropine is an________________ drug - ANSWERS✔-
Anticholinergic
\.MAO-B Inbhitors - ANSWERS✔-Monamine Oxidase B Inhibitors
\.When prescribing MAO-B Inhibitors use CAUTION with what two
medications? - ANSWERS✔-Fluoxetine or Meperidine (Prozac or
Demerol)
\.MAO-B Inhibitors include: - ANSWERS✔-Selegiline (Eldepryl) &
Rasagiline (Azilect)
\.Use MAO-B Inhibitors _____________ and adjunct with __________. -
ANSWERS✔-Early ; Levodopa
\.COMT (Catehcol-O-Methyltransferase Inhibitors) - ANSWERS✔-Help
with uptake of Levodopa which increases dopamine in CNS
