Test Bank for Psychopharmacology: Drugs, the Brain, and Behavior 3rd Edition by Jerrold S. Meyer & Linda F. Quenzer Chapter 1-20 | Complete Guide A+

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Psychopharmacology Drugs the Brain And Behavior 3
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Psychopharmacology,ThirdEdition s

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Chapter 1: Principles of Pharmacology
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Multiple s s Choice

1. refer(s) ssto ssspecific ssmolecular sschanges ssthat ssoccur sswhen ssa ssdrug ssbinds
ssto ssa ssparticular sstarget sssite ssor ssreceptor, sswhile are ssthe ssresulting sswidespread

ssalterations in ssfunction.
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a. Drugssaction; sstherapeutic sseffects
b. Side sseffects; ssdrug sseffects
c. Therapeutic sseffects; ssside sseffects
d. Drug ssaction; ssdrug sseffects
Answer: ssd
Textbook ssReference: ssPharmacology: s s The ssScience ssof ssDrug ssAction

2. After ssdrug ssadministration sshas ssoccurred, ssthe ssamount ssof ssdrug ssin ssthe ssblood ssthat
ssis ssfree sstobind ssat ssspecific sstarget sssites ssis ssreferred ssto ssas

a. the sstherapeutic ssdose.
b. first-pass sseffects.
c. bioavailability.
d. ED50.
Answer: ssc
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

3. The ssspecific ssmolecular sschanges ssthat ssoccur sswhen ssa ssdrug ssbinds ssto ssa ssparticular
sstarget sssite or ssreceptor ssare ssreferred ssto ssas
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a. drugsseffects.
b. drug ssaction.
c. sidesseffects.
d. placebo sseffects.
Answer: ssb
Textbook ssReference: ssPharmacology: ssThe ssScience ssof ssDrug ssAction

4. Which ssof ssthe ssfollowing ssis ssnot ssa sspossible ssexplanation ssfor ssplacebo sseffects?
a. Pavlovian ssconditioning
b. Geneticssvariation
c. Drugsscompetition
d. Expectation ssof ssoutcome
Answer: ssc
Textbook ssReference: ssPharmacology: ssThe ssScience ssof ssDrug ssAction



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5. The administration ssof ssoxytocin sshas ssbeen ssproposed ssas ssa sstreatment ssfor ssautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: ssc
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

6. Which ssfactor ssdoes ssnot ss affect ssthe sspharmacokinetics ssof ssa ssdrug?
a. Route ssof ssadministration
b. Lipid sssolubility
c. Depot ssbinding
d. Drug ssaction
Answer: ssd
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

7. First-pass ssmetabolism ss occurs sswhen ssdrugs ssare sstaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: ssa
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

8. The ssarea sspostrema ssis ssone ssarea ssin ssthe ssbrain sswhere ssthe is ssnot sscomplete.
a. cerebrospinal ssfluid
b. blood–brain ssbarrier
c. choroid ssplexus
d. phospholipid ssmembrane
Answer: ssb
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

9. First-pass ssmetabolism ssoccurs sswith ssorallyssadministered ssdrugs ssbecause
a. their ssabsorption ssis ssslowed ssbyssfood.
b. drugs ssabsorbed ssinto ssthe ssbloodstream ssfrom ssthe ssstomach ssgo ssto ssthe ssliver sson
ssthe ssway sstogeneral sscirculation.

c. drugs ssmust ssfirst sssurvive ssthe ssacidic ssenvironment ssof ssthe ssstomach.
d. salivaryssenzymes ssin ssthe ssmouth ssbegin ssthe ssprocess ss of ssmetabolism.
Answer: ssb
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

10. Toxic sssubstances ssin ssthe ssblood sstrigger ssa ssvomiting ssresponse ssby ssactivating ssthe
a. blood–brain ssbarrier.
b. choroid ssplexus.
c. area sspostrema.
d. median sseminence.




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Answer: ssc
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

11. Drugs ssadministered ss_ have ssthe ssmost ssrapid ssonset ssof ssaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: ssd
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

12. Ionization ssof ssa ssdrug ssdepends sson ssthe of ssthe sssolution ssand ssthe of
ssthedrug.

a. pH; sspKa
b. pKa; sspH
c. concentration; sslipid sssolubility
d. pH; ssconcentration
Answer: ssa
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

13. The ssabsorption ssof ssa ssdrug ssdepends sson ssall ssof ssthe ssfollowing ssexcept
a. lipid sssolubility.
b. ionization.
c. bodysstemperature.
d. the ssconcentration ssof ssthe ssdrug.
Answer: ssc
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

14. Drugs ssthat ssare should ssbe ssavoided ssby sswomen ssof sschildbearing ssage.
a. teratogenic
b. able ssto sscross ssthe ssplacental ssbarrier
c. psychoactive
d. highlysslipid-soluble
Answer: ssa
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

15. Agents ssthat ssinduce ssdevelopmental ssabnormalities ssin ssa ssfetus ssare ssknown ssas
a. psychoactive ssdrugs.
b. illicit ssdrugs.
c. teratogens.
d. placental ssdrugs.
Answer: ssc
Textbook ssReference: ssPharmacokinetic ssFactors ssDetermining ssDrug ssAction

16. Depot ssbinding ssis sssaid ssto ssoccur sswhen ssdrugs
a. bind ssto sstheir sstarget sssites.




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