MU NURS 615 ADVANCED PHARM EXAM 4
PRACTICE PAPER 2026 COMPLETE SOLUTIONS
◉ 5-HT3 Receptor Antagonist (ondansetron) moa: _____ receptor
blockade peripherally and centrally so that the enhanced release of
serotonin due to chemotherapy is blocked Answer: serotonin
◉ 5-HT3 Receptor Antagonist (ondansetron) moa: serotonin
receptor blockade _____ and _____ so that the enhanced release of
serotonin due to chemotherapy is blocked Answer: peripherally and
centrally
◉ What drug/drug class is most effective for motion sickness?
Answer: Antihistamines (dimenhydrinate, diphenhydramine,
meclizine)
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
can cause _____ effects in older adults and agitation in the pediatric
population Answer: anticholinergic (dry mouth, sedation)
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
can cause anticholinergic effects (dry mouth, sedation) in older
adults and _____ in the pediatric population Answer: agitation
, ◉ What drug/drug class can cause anticholinergic effects (dry
mouth, sedation) in older adults and agitation in the pediatric
population? Answer: Antihistamines (dimenhydrinate,
diphenhydramine, meclizine)
◉ What is a BBW for Phenothiazines (promethazine,
prochlorperazine)? Answer: respiratory depression (in pediatric
population)
◉ What are 2 pediatric ADRs of Phenothiazines (promethazine,
prochlorperazine)? Answer: EPS, Respiratory depression
◉ What drug/drug class is contraindicated in Parkinson's disease,
narrow-angle glaucoma, bone marrow depression, cardiovascular
disease, lung disease (chronic bronchitis) (decreased cough reflex-
aspiration risk), and pregnancy? Answer: Phenothiazines
(promethazine, prochlorperazine)
◉ What drug/drug class may cause urine discoloration (pink to
reddish-brown)? Answer: Phenothiazines (promethazine,
prochlorperazine)
◉ What drug/drug class is best for pretreatment to prevent
chemotherapy-induced N/V? Answer: 5-HT3 Receptor Antagonists
(ondansetron)
PRACTICE PAPER 2026 COMPLETE SOLUTIONS
◉ 5-HT3 Receptor Antagonist (ondansetron) moa: _____ receptor
blockade peripherally and centrally so that the enhanced release of
serotonin due to chemotherapy is blocked Answer: serotonin
◉ 5-HT3 Receptor Antagonist (ondansetron) moa: serotonin
receptor blockade _____ and _____ so that the enhanced release of
serotonin due to chemotherapy is blocked Answer: peripherally and
centrally
◉ What drug/drug class is most effective for motion sickness?
Answer: Antihistamines (dimenhydrinate, diphenhydramine,
meclizine)
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
can cause _____ effects in older adults and agitation in the pediatric
population Answer: anticholinergic (dry mouth, sedation)
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
can cause anticholinergic effects (dry mouth, sedation) in older
adults and _____ in the pediatric population Answer: agitation
, ◉ What drug/drug class can cause anticholinergic effects (dry
mouth, sedation) in older adults and agitation in the pediatric
population? Answer: Antihistamines (dimenhydrinate,
diphenhydramine, meclizine)
◉ What is a BBW for Phenothiazines (promethazine,
prochlorperazine)? Answer: respiratory depression (in pediatric
population)
◉ What are 2 pediatric ADRs of Phenothiazines (promethazine,
prochlorperazine)? Answer: EPS, Respiratory depression
◉ What drug/drug class is contraindicated in Parkinson's disease,
narrow-angle glaucoma, bone marrow depression, cardiovascular
disease, lung disease (chronic bronchitis) (decreased cough reflex-
aspiration risk), and pregnancy? Answer: Phenothiazines
(promethazine, prochlorperazine)
◉ What drug/drug class may cause urine discoloration (pink to
reddish-brown)? Answer: Phenothiazines (promethazine,
prochlorperazine)
◉ What drug/drug class is best for pretreatment to prevent
chemotherapy-induced N/V? Answer: 5-HT3 Receptor Antagonists
(ondansetron)
