EXAM SCRIPT 2026 QUESTIONS WITH
◉ What drug is an example of a PPI? Answer: Omeprazole
◉ Famotidine is an example of what drug class? Answer: H2 Blocker
◉ Omeprazole is an example of what drug class? Answer: PPI
◉ H2 blockers moa: block histamine-2 receptors --> decreased _____
Answer: acid
◉ What medications neutralize stomach acid? Answer: Antacids
◉ What are 3 rare side effects of H2 blockers (famotidine)? Answer:
Confusion (elderly), B-12 deficiency/pernicious anemia (long-term),
Thrombocytopenia
◉ What drug/drug class moa?: block H+/K+ ATPase --> decreased
acid secretion Answer: PPI (omeprazole)
,◉ What are 3 standout ADRs of PPIs (omeprazole)? Answer: B12
deficiency/pernicious anemia, increased fracture risk
(osteoporosis), increased C. diff risk (also decreased magnesium,
kidney issues [rare], decreased effects of plavix)
◉ When should H2 Blockers (famotidine) and PPIs (omeprazole) be
taken? Answer: Must be taken first thing in the morning before
eating or drinking to "shut off" the acid pumps
◉ Metoclopramide moa: prokinetic therapy; increases/decreases
gastrointestinal motility without increasing secretions? Answer:
increases
◉ What is a BBW for metoclopramide? Answer: Extrapyramidal
symptoms (EPS)- tardive dyskinesia (younger age at higher risk)
◉ What drug should only be used as an add-on, never first-line, and
used with lowest effective dose for the shortest duration of time?
Answer: metoclopramide
◉ What 3 Antiemetic drugs are examples of Antihistamines?
Answer: Dimenhydrinate, Diphenhydramine, Meclizine
◉ Dimenhydrinate, Diphenhydramine, and Meclizine are examples
of what drug class? Answer: Antihistamines
, ◉ What drug/drug class moa?: bind to histamine-1 receptors -->
decreased secretions in mouth and eyes; bind to central cholinergic
receptors which causes decreased nausea Answer: Antihistamines
(dimenhydrinate, diphenhydramine, meclizine)
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
moa: bind to histamine-1 receptors --> decreased secretions in
mouth and eyes; bind to central _____ receptors which causes
decreased nausea Answer: cholinergic
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
moa: bind to histamine-1 receptors --> decreased secretions in
mouth and eyes; bind to central cholinergic receptors which causes
decreased _____ Answer: nausea
◉ Antihistamines (dimenhydrinate, diphenhydramine, meclizine)
moa: bind to _____-_____ receptors --> decreased secretions in mouth
and eyes; bind to central cholinergic receptors which causes
decreased nausea Answer: histamine-1
◉ What 2 Antiemetic drugs are examples of Phenothiazines?
Answer: Promethazine, Prochlorperazine