NSG 6005 WEEK 1-3 PHARMACOLOGY EXAM
QUESTIONS AND CORRECT ANSWERS LATEST 2026
GRADED A+
The major reason for not crushing a sustained release capsule is that, if crushed,
the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - ANSWER-o Toxicity
Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired action
o Are converted by the liver to more active in fat-soluble forms - ANSWER-o Are
rapidly metabolized by the liver and may have little if any desired action
When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
,o His appropriately only telling you about his regularly prescribed medications
o His hiding information regarding his inappropriate use of aspirin from you
o His common misconception that intermittently taking OTC medications are not
an important part of his drug history
o A common misuse of OTC aspirin - ANSWER-o His common misconception
that intermittently taking OTC medications are not an important part of his drug
history
Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
o Both A and B
o Neither A nor B - ANSWER-o Both A and B
A twenty four year old male received multiple fractures in a motor vehicle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for Type ____ ADR when he no longer requires the opioids.
oA
oC
oE
o G - ANSWER-o E
Infants and young children are at higher risk of ADRs due to:
,o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of topical
medication
o Infant boys having a higher proportion of muscle mass, leading to a higher
volume of distribution - ANSWER-o Lack of safety and efficacy studies in the
pediatric population
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A
o Type B
o Type C
o Type D - ANSWER-o Type A
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
o Liquid ibuprofen does not have to be dosed as often as tablet form. - ANSWER-o
A six-year-old may have problems swallowing a pill.
The role of the nurse practitioner in the use of herbal medication is to:
, o Maintain competence in the prescribing of common herbal remedies.
o Recommend common OTC herbs to patients.
o Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the documented dangers. -
ANSWER-o Educate patients and guide them to appropriate sources of care.
Genetic polymorphisms account for differences in metabolism, including:
o Poor metabolizers (PMs) that lack a working enzyme
o Intermediate metabolizers (IMs) that have one working, wild-type allele and one
mutant allele
o Extensive metabolizers (EMs), with two normally functioning alleles
o All of the above - ANSWER-o All of the above
The elderly are at high risk of ADRs due to:
o Having greater muscle mass than younger adults, leading to higher volume of
distribution
o The extensive studies that have been conducted on drug safety in this age group
o The blood-brain barrier being less permeable, requiring higher doses to achieve
therapeutic effect
o Age-related decrease in renal function - ANSWER-o Age-related decrease in
renal function
QUESTIONS AND CORRECT ANSWERS LATEST 2026
GRADED A+
The major reason for not crushing a sustained release capsule is that, if crushed,
the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - ANSWER-o Toxicity
Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired action
o Are converted by the liver to more active in fat-soluble forms - ANSWER-o Are
rapidly metabolized by the liver and may have little if any desired action
When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
,o His appropriately only telling you about his regularly prescribed medications
o His hiding information regarding his inappropriate use of aspirin from you
o His common misconception that intermittently taking OTC medications are not
an important part of his drug history
o A common misuse of OTC aspirin - ANSWER-o His common misconception
that intermittently taking OTC medications are not an important part of his drug
history
Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
o Both A and B
o Neither A nor B - ANSWER-o Both A and B
A twenty four year old male received multiple fractures in a motor vehicle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for Type ____ ADR when he no longer requires the opioids.
oA
oC
oE
o G - ANSWER-o E
Infants and young children are at higher risk of ADRs due to:
,o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of topical
medication
o Infant boys having a higher proportion of muscle mass, leading to a higher
volume of distribution - ANSWER-o Lack of safety and efficacy studies in the
pediatric population
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A
o Type B
o Type C
o Type D - ANSWER-o Type A
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
o Liquid ibuprofen does not have to be dosed as often as tablet form. - ANSWER-o
A six-year-old may have problems swallowing a pill.
The role of the nurse practitioner in the use of herbal medication is to:
, o Maintain competence in the prescribing of common herbal remedies.
o Recommend common OTC herbs to patients.
o Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the documented dangers. -
ANSWER-o Educate patients and guide them to appropriate sources of care.
Genetic polymorphisms account for differences in metabolism, including:
o Poor metabolizers (PMs) that lack a working enzyme
o Intermediate metabolizers (IMs) that have one working, wild-type allele and one
mutant allele
o Extensive metabolizers (EMs), with two normally functioning alleles
o All of the above - ANSWER-o All of the above
The elderly are at high risk of ADRs due to:
o Having greater muscle mass than younger adults, leading to higher volume of
distribution
o The extensive studies that have been conducted on drug safety in this age group
o The blood-brain barrier being less permeable, requiring higher doses to achieve
therapeutic effect
o Age-related decrease in renal function - ANSWER-o Age-related decrease in
renal function
