TEST BANK For Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition By Meyer Nursing, Verified Chapters 1 - 20, Complete Newest Version

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, Chapter 1: Principles of Pharmacology [+ [+ [+ [+




Multiple Choice [+




1. refer(s) to specific molecular changes that occur when a drug binds to a p
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articular target site or receptor, while
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are the resulting widespread alterations in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects [+ [+ [+


d. Drug action; drug effects
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Answer: d [+


Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free t
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o bind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. [+


c. bioavailability.
d. ED50.
Answer: c [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target sit
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e or receptor are referred to as
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a. drug effects. [+


b. drug action. [+


c. side effects.[+


d. placebo effects. [+


Answer: b [+


Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning [+


b. Genetic variation [+


c. Drug competition [+


d. Expectation of outcome [+ [+


Answer: c [+


Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. [+ [+ [+ [+ [+ [+ [+ [+ [+ [+


a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
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b. Lipid solubility
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c. Depot binding [+


d. Drug action
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Answer: d [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken
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a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
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a. cerebrospinal fluid [+


b. blood–brain barrier [+


c. choroid plexus [+


d. phospholipid membrane [+


Answer: b [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way t
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o general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. [+


b. choroid plexus. [+


c. area postrema.
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d. median eminence. [+




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, Answer: c [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
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of the drug.
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a. pH; pKa
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b. pKa; pH [+


c. concentration; lipid solubility [+ [+


d. pH; concentration
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Answer: a [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
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b. ionization.
c. body temperature.
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d. the concentration of the drug.
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Answer: c [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble [+


Answer: a [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. [+


b. illicit drugs. [+


c. teratogens.
d. placental drugs. [+


Answer: c [+


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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