,Chapter 01: Information Sources, Regulatory Agencies, Drug Legislation, and Prescription Wri
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ting
Haveles: Applied Pharmacology for the Dental Hygienist, 9th Edition
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MULTIPLE CHOICE WQ
1. Knowledge of pharmacology aids the dental professional inWQ WQ WQ WQ WQ WQ WQ
a. obtaining a patient’s health history. WQ WQ WQ WQ
b. administering drugs in the office. WQ WQ WQ WQ
c. handling emergency situations. WQ WQ
d. selection of a nonprescription medication. WQ WQ WQ WQ
e. All of the above. WQ WQ WQ
ANS: E W Q
All of the choices are true. Because many of our patients are being treated with drugs, knowledge of
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
pharmacology helps in understanding and interpreting patients’ responses to health history questions.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Knowledge of the therapeutic and adverse effects of medications obviously helps in their proper adm
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
inistration in the office. Emergency situations may be caused by drugs or treated by drugs; thus, kno
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
wledge of pharmacology is of great help, especially because a rapid response is sometimes required.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
A clear understanding of the concepts of drug action, drug handling by the body, and drug interactio
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ns will allow the dental practitioner to make proper judgments and grasp the concepts relevant to ne
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
w drug therapies on the market.
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DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (Medicati
W Q WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
on Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental Hygienist (
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Nonprescription Medication) | pp. 2-3 OBJ: 1 WQ WQ WQ WQ
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
2. Which of the following statements is true regarding planning appointments?
WQ WQ WQ WQ WQ WQ WQ WQ WQ
a. Whether or not patients are taking medication for systemic diseases is of little
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
consequence in the dental office. WQ WQ WQ WQ
b. Asthmatic patients should have dental appointments in the morning. WQ WQ WQ WQ WQ WQ WQ WQ
c. Diabetic patients usually have fewer problems with a morning appointment co
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
mpared with afternoon appointments. WQ WQ WQ
d. Both B and C are true. WQ WQ WQ WQ WQ
ANS: D W Q
Asthmatic patients who experience dental anxiety should schedule their appointments when they are
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
not rushed or under pressure early in the morning. Diabetic patients usually have relatively fewer pro
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
blems with a morning appointment. Patients taking medication for systemic diseases may require spe
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
cial handling in the dental office.
WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling) | p.
W Q WQ WQ WQ WQ WQ WQ WQ WQ W
3 OBJ: 1
Q WQ TOP: NBDHE, 6.0. Pharmacology
W Q W Q WQ WQ
,3. Nutritional or herbal supplements WQ WQ WQ
a. carry the U.S. Food and Drug Administration (FDA) approval for disease states.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
b. are not drugs. WQ WQ
c. can cause adverse effects. WQ WQ WQ
d. will not interact with other drugs the patient may be taking.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ANS: C W Q
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of nutritio
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
nal or herbal supplements do not carry FDA approval for treating disease states. These supplements ar
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
e drugs and can cause adverse effects and interact with different drugs.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements) | p.
W Q WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ W
3 OBJ: 1
Q WQ TOP: NBDHE, 6.0. Pharmacology
W Q W Q WQ WQ
4. Which type of drug name usually begins with a lowercase letter?
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
a. Brand name WQ
b. Code name WQ
c. Generic name WQ
d. Trade name WQ
ANS: C W Q
Before any drug is marketed, it is given a generic name that becomes the “official” name of the drug.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ W
Each drug is assigned only one generic name selected by the U.S. Adopted Name Council, and the n
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ame is not capitalized. The brand name is equivalent to the trade name and is capitalized. Although t
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
he brand name is technically the name of the company marketing the product, this term is often used i
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
nterchangeably with the trade name. The code name is the initial term used within a pharmaceutical
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
company to refer to a drug while it is undergoing investigation and is often a combination of capital
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
letters and numbers, the letters representing an abbreviation of the company name.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3 W Q WQ WQ WQ WQ WQ W Q
TOP: NBDHE, 6.0. Pharmacology W Q WQ WQ
5. A drug’s generic name is selected by the
WQ WQ WQ WQ WQ WQ WQ
a. pharmaceutical company manufacturing it. WQ WQ WQ
b. Food and Drug Administration (FDA). WQ WQ WQ WQ
c. U.S. Adopted Name Council. WQ WQ WQ
d. Federal Patent Office. WQ WQ
ANS: C W Q
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Adopted Na
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
me Council. The generic name is not selected by the FDA or the Federal Patent Office. The pharmac
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
eutical company manufacturing the drug clearly has an influence on the generic name given its drug,
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
but the final decision is not the company’s.
WQ WQ WQ WQ WQ WQ WQ
DIF: Recall REF: Drug Names | p. 4 W Q WQ WQ WQ WQ
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
W Q WQ W Q WQ WQ
6. Which of the following is true concerning generic and trade names of drugs?
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a. A drug may only have one generic name and one trade name.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
, b. A drug may only have one generic name, but it may have several trade names
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
.
c. A drug may have several generic names, but it may only have one trade name
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
.
d. A drug may have several generic names and several trade names.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ANS: B W Q
Each drug has only one generic name but may have several trade names. For each drug, there is only
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
one generic name. It is not capitalized, and it becomes the “official” name of the drug. The pharmace
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
utical company discovering the drug gives the drug a trade name. The trade name is protected by the
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Federal Patent Law for 20 years from the earliest claimed filing date, plus patent term extensions. Alt
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
hough the brand name is technically the name of the company marketing the product, it is often used
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
interchangeably with the trade name. WQ WQ WQ WQ
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
W Q WQ WQ WQ WQ WQ W Q
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
7. Two drugs that are found to be chemically equivalent, but not biologically equivalent or
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
therapeutically equivalent are said to differ in
WQ WQ WQ WQ WQ WQ WQ
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. WQ
ANS: C W Q
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent. These
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
products are said to differ in their bioavailability. The potency of a drug is a function of the amount o
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
f drug required to produce an effect. The efficacy is the maximum intensity of effect or response that
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
can be produced by a drug. The therapeutic index is the ratio of the lethal dose for 50% of the exper
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
imental animals divided by the effective dose for 50% of the experimental animals. If the value of th
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
e therapeutic index is small, toxicity is more likely.
WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
W Q WQ WQ WQ WQ WQ WQ WQ W Q 4
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
8. How many years must pass after a drug patent expires before other drug companies can market th
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e same compound as a generic drug?
WQ WQ WQ WQ WQ WQ
a. 20 years WQ
b. 17 years WQ
c. 7 years WQ
d. 0 years WQ
ANS: D W Q
Once a drug patent expires, competing companies may immediately market the same compound in g
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
eneric form. The pharmaceutical company discovering the drug gives the drug a trade name. The tra
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
de name is protected by the Federal Patent Law for 20 years from the earliest claimed filing date, plus
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
the patent term extensions.
WQ WQ WQ WQ
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
W Q WQ WQ WQ WQ WQ WQ WQ W Q 4
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ting
Haveles: Applied Pharmacology for the Dental Hygienist, 9th Edition
WQ WQ WQ WQ WQ WQ WQ WQ
MULTIPLE CHOICE WQ
1. Knowledge of pharmacology aids the dental professional inWQ WQ WQ WQ WQ WQ WQ
a. obtaining a patient’s health history. WQ WQ WQ WQ
b. administering drugs in the office. WQ WQ WQ WQ
c. handling emergency situations. WQ WQ
d. selection of a nonprescription medication. WQ WQ WQ WQ
e. All of the above. WQ WQ WQ
ANS: E W Q
All of the choices are true. Because many of our patients are being treated with drugs, knowledge of
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
pharmacology helps in understanding and interpreting patients’ responses to health history questions.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Knowledge of the therapeutic and adverse effects of medications obviously helps in their proper adm
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
inistration in the office. Emergency situations may be caused by drugs or treated by drugs; thus, kno
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
wledge of pharmacology is of great help, especially because a rapid response is sometimes required.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
A clear understanding of the concepts of drug action, drug handling by the body, and drug interactio
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ns will allow the dental practitioner to make proper judgments and grasp the concepts relevant to ne
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
w drug therapies on the market.
WQ WQ WQ WQ WQ
DIF: Application
REF: Role of the Dental Hygienist (Medication/Health History), Role of the Dental Hygienist (Medicati
W Q WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
on Administration), Role of the Dental Hygienist (Emergency Situations), Role of the Dental Hygienist (
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Nonprescription Medication) | pp. 2-3 OBJ: 1 WQ WQ WQ WQ
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
2. Which of the following statements is true regarding planning appointments?
WQ WQ WQ WQ WQ WQ WQ WQ WQ
a. Whether or not patients are taking medication for systemic diseases is of little
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
consequence in the dental office. WQ WQ WQ WQ
b. Asthmatic patients should have dental appointments in the morning. WQ WQ WQ WQ WQ WQ WQ WQ
c. Diabetic patients usually have fewer problems with a morning appointment co
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
mpared with afternoon appointments. WQ WQ WQ
d. Both B and C are true. WQ WQ WQ WQ WQ
ANS: D W Q
Asthmatic patients who experience dental anxiety should schedule their appointments when they are
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
not rushed or under pressure early in the morning. Diabetic patients usually have relatively fewer pro
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
blems with a morning appointment. Patients taking medication for systemic diseases may require spe
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
cial handling in the dental office.
WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Role of the Dental Hygienist (Appointment Scheduling) | p.
W Q WQ WQ WQ WQ WQ WQ WQ WQ W
3 OBJ: 1
Q WQ TOP: NBDHE, 6.0. Pharmacology
W Q W Q WQ WQ
,3. Nutritional or herbal supplements WQ WQ WQ
a. carry the U.S. Food and Drug Administration (FDA) approval for disease states.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
b. are not drugs. WQ WQ
c. can cause adverse effects. WQ WQ WQ
d. will not interact with other drugs the patient may be taking.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ANS: C W Q
Nutritional or herbal supplements are quite capable of causing adverse effects. The majority of nutritio
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
nal or herbal supplements do not carry FDA approval for treating disease states. These supplements ar
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
e drugs and can cause adverse effects and interact with different drugs.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Role of the Dental Hygienist (Nutritional or Herbal Supplements) | p.
W Q WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ W
3 OBJ: 1
Q WQ TOP: NBDHE, 6.0. Pharmacology
W Q W Q WQ WQ
4. Which type of drug name usually begins with a lowercase letter?
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
a. Brand name WQ
b. Code name WQ
c. Generic name WQ
d. Trade name WQ
ANS: C W Q
Before any drug is marketed, it is given a generic name that becomes the “official” name of the drug.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ W
Each drug is assigned only one generic name selected by the U.S. Adopted Name Council, and the n
Q WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ame is not capitalized. The brand name is equivalent to the trade name and is capitalized. Although t
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
he brand name is technically the name of the company marketing the product, this term is often used i
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
nterchangeably with the trade name. The code name is the initial term used within a pharmaceutical
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
company to refer to a drug while it is undergoing investigation and is often a combination of capital
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
letters and numbers, the letters representing an abbreviation of the company name.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3 W Q WQ WQ WQ WQ WQ W Q
TOP: NBDHE, 6.0. Pharmacology W Q WQ WQ
5. A drug’s generic name is selected by the
WQ WQ WQ WQ WQ WQ WQ
a. pharmaceutical company manufacturing it. WQ WQ WQ
b. Food and Drug Administration (FDA). WQ WQ WQ WQ
c. U.S. Adopted Name Council. WQ WQ WQ
d. Federal Patent Office. WQ WQ
ANS: C W Q
Each drug is assigned only one generic name (e.g., ibuprofen). It is selected by the U.S. Adopted Na
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
me Council. The generic name is not selected by the FDA or the Federal Patent Office. The pharmac
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
eutical company manufacturing the drug clearly has an influence on the generic name given its drug,
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
but the final decision is not the company’s.
WQ WQ WQ WQ WQ WQ WQ
DIF: Recall REF: Drug Names | p. 4 W Q WQ WQ WQ WQ
OBJ: 3 TOP: NBDHE, 6.0. Pharmacology
W Q WQ W Q WQ WQ
6. Which of the following is true concerning generic and trade names of drugs?
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
a. A drug may only have one generic name and one trade name.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
, b. A drug may only have one generic name, but it may have several trade names
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
.
c. A drug may have several generic names, but it may only have one trade name
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
.
d. A drug may have several generic names and several trade names.
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
ANS: B W Q
Each drug has only one generic name but may have several trade names. For each drug, there is only
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
one generic name. It is not capitalized, and it becomes the “official” name of the drug. The pharmace
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
utical company discovering the drug gives the drug a trade name. The trade name is protected by the
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
Federal Patent Law for 20 years from the earliest claimed filing date, plus patent term extensions. Alt
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
hough the brand name is technically the name of the company marketing the product, it is often used
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
interchangeably with the trade name. WQ WQ WQ WQ
DIF: Comprehension
REF: Drug Names | p. 4 OBJ: 3
W Q WQ WQ WQ WQ WQ W Q
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
7. Two drugs that are found to be chemically equivalent, but not biologically equivalent or
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
therapeutically equivalent are said to differ in
WQ WQ WQ WQ WQ WQ WQ
a. potency.
b. efficacy.
c. bioavailability.
d. therapeutic index. WQ
ANS: C W Q
A preparation can be chemically equivalent yet not biologically or therapeutically equivalent. These
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
products are said to differ in their bioavailability. The potency of a drug is a function of the amount o
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
f drug required to produce an effect. The efficacy is the maximum intensity of effect or response that
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
can be produced by a drug. The therapeutic index is the ratio of the lethal dose for 50% of the exper
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
imental animals divided by the effective dose for 50% of the experimental animals. If the value of th
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
e therapeutic index is small, toxicity is more likely.
WQ WQ WQ WQ WQ WQ WQ WQ
DIF: Recall
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
W Q WQ WQ WQ WQ WQ WQ WQ W Q 4
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ
8. How many years must pass after a drug patent expires before other drug companies can market th
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
e same compound as a generic drug?
WQ WQ WQ WQ WQ WQ
a. 20 years WQ
b. 17 years WQ
c. 7 years WQ
d. 0 years WQ
ANS: D W Q
Once a drug patent expires, competing companies may immediately market the same compound in g
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
eneric form. The pharmaceutical company discovering the drug gives the drug a trade name. The tra
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
de name is protected by the Federal Patent Law for 20 years from the earliest claimed filing date, plus
WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ WQ
the patent term extensions.
WQ WQ WQ WQ
DIF: Application
REF: Drug Names (Drug Substitution) | p. 5 OBJ:
W Q WQ WQ WQ WQ WQ WQ WQ W Q 4
TOP: NBDHE, 6.0. Pharmacology
W Q WQ WQ