gvgTestvgBank
,PsychopharmacologyvgDrugsvgthevgBrainvgAndvgBehaviorvg3rdvgEditionvgmeyervgNurs
ingvgTestvgBank
TestvgBank
tovgaccompany
Psychopharmacology,vgThirdvgEdition
Meyervg•vgQuenzer
Chapter 1: Principles of Pharmacology
vg vg vg vg
MultiplevgChoice
1. refer(s)vgtovgspecificvgmolecularvgchangesvgthatvgoccurvgwhenvgavgdrugvgbindsvgt
ovgavgparticularvgtargetvgsitevgorvgreceptor,vgwhile
arevgthevgresultingvgwidespreadvgalterationsvginvgfunction.
a. Drugvgaction;vgtherapeuticvgeffects
b. Sidevgeffects;vgdrugvgeffects
c. Therapeuticvgeffects;vgsidevgeffects
d. Drugvgaction;vgdrugvgeffects
Answer:vgd
TextbookvgReference:vgPharmacology:vgThevgSciencevgofvgDrugvgAction
2. Aftervgdrugvgadministrationvghasvgoccurred,vgthevgamountvgofvgdrugvginvgthevgbloodvgthat
vgisvgfreevgtovgbindvgatvgspecificvgtargetvgsitesvgisvgreferredvgtovgas
a. thevgtherapeuticvgdose.
b. first-passvgeffects.
c. bioavailability.
d. ED50.
Answer:vgc
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
3. Thevgspecificvgmolecularvgchangesvgthatvgoccurvgwhenvgavgdrugvgbindsvgtovgavgparticula
rvgtargetvgsitevgorvgreceptorvgarevgreferredvgtovgas
a. drugvgeffects.
b. drugvgaction.
c. sidevgeffects.
d. placebovgeffects.
Answer:vgb
TextbookvgReference:vgPharmacology:vgThevgSciencevgofvgDrugvgAction
4. Whichvgofvgthevgfollowingvgisvgnotvgavgpossiblevgexplanationvgforvgplacebovgeffects?
a. Pavlovianvgconditioning
b. Geneticvgvariation
c. Drugvgcompetition
d. Expectationvgofvgoutcome
Answer:vgc
TextbookvgReference:vgPharmacology:vgThevgSciencevgofvgDrugvgAction
WWW.THENURSINGMASTERY.COM
Pagevg1vgofvg247
,PsychopharmacologyvgDrugsvgthevgBrainvgAndvgBehaviorvg3rdvgEditionvgmeyervgNurs
ingvgTestvgBank
5. The administrationvgofvgoxytocinvghasvgbeenvgproposedvgasvgavgtreatmentvgforvgautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:vgc
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
6. Whichvgfactorvgdoesvgnotvgaffectvgthevgpharmacokineticsvgofvgavgdrug?
a. Routevgofvgadministration
b. Lipidvgsolubility
c. Depotvgbinding
d. Drugvgaction
Answer:vgd
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
7. First-passvgmetabolismvgoccursvgwhenvgdrugsvgarevgtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:vga
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
8. Thevgareavgpostremavgisvgonevgareavginvgthevgbrainvgwherevgthe isvgnotvgcomplete.
a. cerebrospinalvgfluid
b. blood–brainvgbarrier
c. choroidvgplexus
d. phospholipidvgmembrane
Answer:vgb
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
9. First-passvgmetabolismvgoccursvgwithvgorallyvgadministeredvgdrugsvgbecause
a. theirvgabsorptionvgisvgslowedvgbyvgfood.
b. drugsvgabsorbedvgintovgthevgbloodstreamvgfromvgthevgstomachvggovgtovgthevglivervgonvg
thevgwayvgtovggeneralvgcirculation.
c. drugsvgmustvgfirstvgsurvivevgthevgacidicvgenvironmentvgofvgthevgstomach.
d. salivaryvgenzymesvginvgthevgmouthvgbeginvgthevgprocessvgofvgmetabolism.
Answer:vgb
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
10. Toxicvgsubstancesvginvgthevgbloodvgtriggervgavgvomitingvgresponsevgbyvgactivatingvgthe
a. blood–brainvgbarrier.
b. choroidvgplexus.
c. areavgpostrema.
d. medianvgeminence.
WWW.THENURSINGMASTERY.COM
Pagevg2vgofvg247
, PsychopharmacologyvgDrugsvgthevgBrainvgAndvgBehaviorvg3rdvgEditionvgmeyervgNurs
ingvgTestvgBank
Answer:vgc
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
11. Drugsvgadministeredvg_ havevgthevgmostvgrapidvgonsetvgofvgaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:vgd
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
12. Ionizationvgofvgavgdrugvgdependsvgonvgthe ofvgthevgsolutionvgandvgthe
ofvgthevgdrug.
a.v g pH;vgpK
a
b.v g v g pK ;vgpH
a
c.
v g concentration;vglipidvgsolubility
d.
v g pH;vgconcentration
Answer:vga
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
13. Thevgabsorptionvgofvgavgdrugvgdependsvgonvgallvgofvgthevgfollowingvgexcept
a. lipidvgsolubility.
b. ionization.
c. bodyvgtemperature.
d. thevgconcentrationvgofvgthevgdrug.
Answer:vgc
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
14. Drugsvgthatvgare shouldvgbevgavoidedvgbyvgwomenvgofvgchildbearingvgage.
a. teratogenic
b. ablevgtovgcrossvgthevgplacentalvgbarrier
c. psychoactive
d. highlyvglipid-soluble
Answer:vga
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
15. Agentsvgthatvginducevgdevelopmentalvgabnormalitiesvginvgavgfetusvgarevgknownvgas
a. psychoactivevgdrugs.
b. illicitvgdrugs.
c. teratogens.
d. placentalvgdrugs.
Answer:vgc
TextbookvgReference:vgPharmacokineticvgFactorsvgDeterminingvgDrugvgAction
16. Depotvgbindingvgisvgsaidvgtovgoccurvgwhenvgdrugs
a. bindvgtovgtheirvgtargetvgsites.
WWW.THENURSINGMASTERY.COM
Pagevg3vgofvg247