OpenStax Microbiology Test Bank
Chapter 18: Adaptive Specific Host Defenses
Chapter 18: Adaptive Specific Host Defenses
* = Correct answer
Multiple Choice
1. Which of the following are the primary cells involved in the adaptive immune system?
A. dendritic cells
B. eosinophils
C. lymphocytes*
D. macrophages
Difficulty: Easy
ASM Standard: 14
2. Antibodies are made up of which of the following?
A. carbohydrates
B. glycoproteins*
C. lipids
D. nucleic acids
Difficulty: Easy
ASM Standard: 14
3. Which molecular fragment on an antigen molecule do antibodies recognize and respond to?
A. epitope*
B. Fab region
C. Fc region
D. variable region
Difficulty: Easy
ASM Standard: N/A
4. A molecule that is too small to be antigen is known as a(n) ________. These molecules are
typically associated with ________.
A. adjuvant; allergies
B. adjuvant; viruses
C. hapten; allergies*
D. hapten; viruses
Difficulty: Moderate
ASM Standard: 7
5. Which class of antibody is the most abundant in serum?
A. IgA
B. IgE
Page 1 of 16
,OpenStax Microbiology Test Bank
Chapter 18: Adaptive Specific Host Defenses
C. IgG*
D. IgM
Difficulty: Moderate
ASM Standard: N/A
6. Which class of antibody provides protection against parasitic pathogens?
A. IgA
B. IgE*
C. IgG
D. IgM
Difficulty: Moderate
ASM Standard: N/A
7. On an antibody, where do phagocytic cells bind during antibody-mediated opsonization?
A. disulfide bond
B. Fab region
C. Fc region*
D. variable region
Difficulty: Easy
ASM Standard: 14
8. Which MHC class is mostly likely found on macrophages?
A. class I
B. class II*
C. both class I and class II
D. neither class I nor class II
Difficulty: Easy
ASM Standard: N/A
9. Which cells do not express MHCs?
A. erythrocytes*
B. hepatocytes
C. intestinal epithelial cells
D. leukocytes
Difficulty: Hard
ASM Standard: N/A
10. Which process describes the cross-linking of pathogens by antibodies so the kidney and
spleen can filter them from the blood?
A. agglutination*
B. complementation
Page 2 of 16
, OpenStax Microbiology Test Bank
Chapter 18: Adaptive Specific Host Defenses
C. neutralization
D. transformation
Difficulty: Moderate
ASM Standard: 14
12. Which complement cascade begins with antibodies binding to a pathogen?
A. alternative only
B. classical only*
C. lectin only
D. all three pathways (alternative, classic, and lectin)
Difficulty: Hard
ASM Standard: 14
13. T cells mature in which location?
A. bone marrow
B. testes
C. thymus*
D. thyroid
Difficulty: Easy
ASM Standard: 14
14. A cell that has been infected with an intracellular pathogen will be targeted for destruction by
which type of lymphocyte?
A. B cell
B. CD4+ regulatory T cell
C. CD8+ cytotoxic T cell*
D. plasma cell
Difficulty: Moderate
ASM Standard: 14, 23
15. Helper T cells are activated by which of the following?
A. MHC class I
B. MHC class II*
C. either MHC class I or class II
D. both MHC class I and class II presenting the same antigen
Difficulty: Easy
ASM Standard: 14
16. Cytotoxic T cells are activated by which of the following?
A. MHC class I*
B. MHC class II
Page 3 of 16
Chapter 18: Adaptive Specific Host Defenses
Chapter 18: Adaptive Specific Host Defenses
* = Correct answer
Multiple Choice
1. Which of the following are the primary cells involved in the adaptive immune system?
A. dendritic cells
B. eosinophils
C. lymphocytes*
D. macrophages
Difficulty: Easy
ASM Standard: 14
2. Antibodies are made up of which of the following?
A. carbohydrates
B. glycoproteins*
C. lipids
D. nucleic acids
Difficulty: Easy
ASM Standard: 14
3. Which molecular fragment on an antigen molecule do antibodies recognize and respond to?
A. epitope*
B. Fab region
C. Fc region
D. variable region
Difficulty: Easy
ASM Standard: N/A
4. A molecule that is too small to be antigen is known as a(n) ________. These molecules are
typically associated with ________.
A. adjuvant; allergies
B. adjuvant; viruses
C. hapten; allergies*
D. hapten; viruses
Difficulty: Moderate
ASM Standard: 7
5. Which class of antibody is the most abundant in serum?
A. IgA
B. IgE
Page 1 of 16
,OpenStax Microbiology Test Bank
Chapter 18: Adaptive Specific Host Defenses
C. IgG*
D. IgM
Difficulty: Moderate
ASM Standard: N/A
6. Which class of antibody provides protection against parasitic pathogens?
A. IgA
B. IgE*
C. IgG
D. IgM
Difficulty: Moderate
ASM Standard: N/A
7. On an antibody, where do phagocytic cells bind during antibody-mediated opsonization?
A. disulfide bond
B. Fab region
C. Fc region*
D. variable region
Difficulty: Easy
ASM Standard: 14
8. Which MHC class is mostly likely found on macrophages?
A. class I
B. class II*
C. both class I and class II
D. neither class I nor class II
Difficulty: Easy
ASM Standard: N/A
9. Which cells do not express MHCs?
A. erythrocytes*
B. hepatocytes
C. intestinal epithelial cells
D. leukocytes
Difficulty: Hard
ASM Standard: N/A
10. Which process describes the cross-linking of pathogens by antibodies so the kidney and
spleen can filter them from the blood?
A. agglutination*
B. complementation
Page 2 of 16
, OpenStax Microbiology Test Bank
Chapter 18: Adaptive Specific Host Defenses
C. neutralization
D. transformation
Difficulty: Moderate
ASM Standard: 14
12. Which complement cascade begins with antibodies binding to a pathogen?
A. alternative only
B. classical only*
C. lectin only
D. all three pathways (alternative, classic, and lectin)
Difficulty: Hard
ASM Standard: 14
13. T cells mature in which location?
A. bone marrow
B. testes
C. thymus*
D. thyroid
Difficulty: Easy
ASM Standard: 14
14. A cell that has been infected with an intracellular pathogen will be targeted for destruction by
which type of lymphocyte?
A. B cell
B. CD4+ regulatory T cell
C. CD8+ cytotoxic T cell*
D. plasma cell
Difficulty: Moderate
ASM Standard: 14, 23
15. Helper T cells are activated by which of the following?
A. MHC class I
B. MHC class II*
C. either MHC class I or class II
D. both MHC class I and class II presenting the same antigen
Difficulty: Easy
ASM Standard: 14
16. Cytotoxic T cells are activated by which of the following?
A. MHC class I*
B. MHC class II
Page 3 of 16
