Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
1. Which principle best characterizes modern medical practice
as described in Harrison’s?
A. Disease-centered decision-making
B. Exclusive reliance on technology
C. Integration of scientific evidence with patient values
D. Standardized care without individualization
Correct Answer: C
Rationale: Harrison’s emphasizes combining evidence-based
medicine with patient preferences and values to guide care.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 The Practice of Medicine
2. Promoting Good Health
2. Which nursing intervention most directly supports health
promotion at the population level?
A. Treating acute illness promptly
B. Encouraging lifestyle modification to reduce risk factors
C. Increasing diagnostic testing
D. Specializing care delivery
Correct Answer: B
Rationale: Health promotion focuses on modifying behaviors
(e.g., diet, activity, smoking) to prevent disease.
Citation: Harrison’s, 22nd ed., Ch. 2 Promoting Good Health
3. Vaccine Opposition and Hesitancy
3. The most effective approach to vaccine hesitancy
recommended in Harrison’s is:
A. Confrontational correction
B. Withholding care
C. Respectful, evidence-based dialogue addressing concerns
D. Legal enforcement
Correct Answer: C
Rationale: Trust-building communication improves vaccine
,acceptance more than coercion.
Citation: Harrison’s, 22nd ed., Ch. 3 Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
4. Shared decision-making is most appropriate when:
A. Evidence strongly favors one option
B. Patient values do not affect outcomes
C. Multiple reasonable options exist
D. Time constraints prohibit discussion
Correct Answer: C
Rationale: When benefits and risks vary by patient preference,
shared decision-making is essential.
Citation: Harrison’s, 22nd ed., Ch. 4 Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Use genetic and biologic data to tailor care
C. Eliminate population-based recommendations
D. Reduce diagnostic testing
Correct Answer: B
Rationale: Precision medicine integrates genomic and
, molecular data to individualize diagnosis and treatment.
Citation: Harrison’s, 22nd ed., Ch. 5 Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
6. A key requirement for an effective screening test is that it:
A. Detects rare conditions only
B. Has high specificity but low sensitivity
C. Improves outcomes through early detection
D. Is inexpensive regardless of accuracy
Correct Answer: C
Rationale: Screening must lead to improved morbidity or
mortality, not just earlier diagnosis.
Citation: Harrison’s, 22nd ed., Ch. 6 Screening and Prevention of
Disease
7. The Safety and Quality of Health Care
7. Most medical errors are attributed to:
A. Individual incompetence
B. System-level failures
C. Patient nonadherence
D. Equipment malfunction alone
Correct Answer: B
Rationale: Harrison’s emphasizes systems-based causes over
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
1. Which principle best characterizes modern medical practice
as described in Harrison’s?
A. Disease-centered decision-making
B. Exclusive reliance on technology
C. Integration of scientific evidence with patient values
D. Standardized care without individualization
Correct Answer: C
Rationale: Harrison’s emphasizes combining evidence-based
medicine with patient preferences and values to guide care.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 The Practice of Medicine
2. Promoting Good Health
2. Which nursing intervention most directly supports health
promotion at the population level?
A. Treating acute illness promptly
B. Encouraging lifestyle modification to reduce risk factors
C. Increasing diagnostic testing
D. Specializing care delivery
Correct Answer: B
Rationale: Health promotion focuses on modifying behaviors
(e.g., diet, activity, smoking) to prevent disease.
Citation: Harrison’s, 22nd ed., Ch. 2 Promoting Good Health
3. Vaccine Opposition and Hesitancy
3. The most effective approach to vaccine hesitancy
recommended in Harrison’s is:
A. Confrontational correction
B. Withholding care
C. Respectful, evidence-based dialogue addressing concerns
D. Legal enforcement
Correct Answer: C
Rationale: Trust-building communication improves vaccine
,acceptance more than coercion.
Citation: Harrison’s, 22nd ed., Ch. 3 Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
4. Shared decision-making is most appropriate when:
A. Evidence strongly favors one option
B. Patient values do not affect outcomes
C. Multiple reasonable options exist
D. Time constraints prohibit discussion
Correct Answer: C
Rationale: When benefits and risks vary by patient preference,
shared decision-making is essential.
Citation: Harrison’s, 22nd ed., Ch. 4 Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Use genetic and biologic data to tailor care
C. Eliminate population-based recommendations
D. Reduce diagnostic testing
Correct Answer: B
Rationale: Precision medicine integrates genomic and
, molecular data to individualize diagnosis and treatment.
Citation: Harrison’s, 22nd ed., Ch. 5 Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
6. A key requirement for an effective screening test is that it:
A. Detects rare conditions only
B. Has high specificity but low sensitivity
C. Improves outcomes through early detection
D. Is inexpensive regardless of accuracy
Correct Answer: C
Rationale: Screening must lead to improved morbidity or
mortality, not just earlier diagnosis.
Citation: Harrison’s, 22nd ed., Ch. 6 Screening and Prevention of
Disease
7. The Safety and Quality of Health Care
7. Most medical errors are attributed to:
A. Individual incompetence
B. System-level failures
C. Patient nonadherence
D. Equipment malfunction alone
Correct Answer: B
Rationale: Harrison’s emphasizes systems-based causes over
