ANTI-MALARIALS
COMPILED BY SOHIL SIDHLALL
, DISCLAIMER
These notes are independently prepared, student-made
study summaries created for educational purposes.
The content is based on standard pharmacology
references, including Katzung’s Basic and Clinical
Pharmacology (12th Edition), but is written entirely in
the author’s own words.
These notes are not copied from, endorsed by, or
affiliated with any textbook, author, publisher, or
institution.
,MEDICATION
Quinine
Chloroquine
Artemisinin and Its Derivatives
Mefloquine
Primaquine
Halofantrine
, QUININE
The first antimalarial drug was discovered in the early 1820s, originally
used to treat fevers.
It’s a natural alkaloid extracted from the bark of the Cinchona tree.
Quinidine is the dextrorotatory isomer of quinine and shares similar
pharmacologic actions.