Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Harrison’s Principles of Internal Medicine, 22nd Edition
(Volumes 1 & 2). The questions are designed for medical-
surgical nursing students, focusing on nursing assessment,
clinical judgment, safety, and priorities of care.
1. A nurse is providing education to a healthy adult patient
about integrating principles of good health into daily life. Which
statement by the patient indicates a correct understanding of a
core concept discussed in this context?
A. "I should aim for at least 150 minutes of moderate-intensity
exercise each week."
,B. "Taking a daily multivitamin is the most important thing I can
do for my health."
C. "I will schedule an annual full-body MRI scan to catch any
disease early."
D. "Preventive health is only important after the age of 50."
Answer: A
Rationale: Promoting good health emphasizes lifestyle
modifications, including regular physical activity. Public health
guidelines consistently support 150 minutes of moderate-
intensity aerobic activity per week as a foundation for disease
prevention and health promotion (Harrison’s Principles of
Internal Medicine, 22nd ed., Chapter 2: Promoting Good
Health).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 2: Promoting Good Health.
2. A nurse is preparing to administer the influenza vaccine to a
patient who states, "I got the flu from the shot last year." What
is the nurse's best response, based on understanding common
reasons for vaccine hesitancy?
A. "You must be mistaken; that is scientifically impossible."
B. "The vaccine contains an inactivated virus that cannot cause
the flu. What you likely experienced was a mild immune
response or contracted a different respiratory virus."
C. "We can skip it this year since you had a bad experience."
D. "You probably had a severe allergic reaction."
Answer: B
Rationale: A common misconception is that vaccines cause the
,illness they aim to prevent. Providing accurate, empathetic
education about the nature of inactivated vaccines and
differentiating side effects (like myalgia or low-grade fever) from
actual disease is a key nursing intervention to address hesitancy
(Harrison’s Principles of Internal Medicine, 22nd ed., Chapter 3:
Vaccine Opposition and Hesitancy).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 3: Vaccine Opposition and Hesitancy.
3. A nurse is caring for a patient newly diagnosed with
hypertension who is overwhelmed by treatment options. When
applying shared decision-making, the nurse's priority action is
to:
A. Provide the patient with a detailed list of all possible
antihypertensive medications.
B. Assess the patient's values, preferences, and capacity to
understand the information.
C. Contact the physician to select the best medication for the
patient.
D. Instruct the patient to follow the standard protocol without
question for safety.
Answer: B
Rationale: Effective shared decision-making in clinical medicine
begins with understanding the patient's individual context—
their goals, concerns, and comprehension level. This aligns with
patient-centered care and ethical practice, forming the
foundation for collaborative planning (Harrison’s Principles of
Internal Medicine, 22nd ed., Chapter 4: Decision-Making in
, Clinical Medicine).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 4: Decision-Making in Clinical Medicine.
4. When discussing the concept of precision medicine with a
patient who has a strong family history of breast cancer, the
nurse should explain that it primarily involves:
A. Using population-based guidelines for all patients with the
same diagnosis.
B. Tailoring prevention and treatment strategies based on the
individual’s genetic, biomarker, and phenotypic profile.
C. Replacing all traditional therapies with novel gene therapies.
D. Focusing solely on palliative and supportive care.
Answer: B
Rationale: Precision medicine aims to customize healthcare by
using molecular and genomic information to guide decisions
about prevention, diagnosis, and treatment for individual
patients, moving beyond a "one-size-fits-all" approach
(Harrison’s Principles of Internal Medicine, 22nd ed., Chapter 5:
Precision Medicine and Clinical Care).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 5: Precision Medicine and Clinical Care.
5. Which factor is most critical for a nurse to consider when
evaluating the appropriateness of a screening test for an
asymptomatic patient?
A. The cost of the test to the healthcare facility.
B. Whether the test is new and technologically advanced.
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Harrison’s Principles of Internal Medicine, 22nd Edition
(Volumes 1 & 2). The questions are designed for medical-
surgical nursing students, focusing on nursing assessment,
clinical judgment, safety, and priorities of care.
1. A nurse is providing education to a healthy adult patient
about integrating principles of good health into daily life. Which
statement by the patient indicates a correct understanding of a
core concept discussed in this context?
A. "I should aim for at least 150 minutes of moderate-intensity
exercise each week."
,B. "Taking a daily multivitamin is the most important thing I can
do for my health."
C. "I will schedule an annual full-body MRI scan to catch any
disease early."
D. "Preventive health is only important after the age of 50."
Answer: A
Rationale: Promoting good health emphasizes lifestyle
modifications, including regular physical activity. Public health
guidelines consistently support 150 minutes of moderate-
intensity aerobic activity per week as a foundation for disease
prevention and health promotion (Harrison’s Principles of
Internal Medicine, 22nd ed., Chapter 2: Promoting Good
Health).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 2: Promoting Good Health.
2. A nurse is preparing to administer the influenza vaccine to a
patient who states, "I got the flu from the shot last year." What
is the nurse's best response, based on understanding common
reasons for vaccine hesitancy?
A. "You must be mistaken; that is scientifically impossible."
B. "The vaccine contains an inactivated virus that cannot cause
the flu. What you likely experienced was a mild immune
response or contracted a different respiratory virus."
C. "We can skip it this year since you had a bad experience."
D. "You probably had a severe allergic reaction."
Answer: B
Rationale: A common misconception is that vaccines cause the
,illness they aim to prevent. Providing accurate, empathetic
education about the nature of inactivated vaccines and
differentiating side effects (like myalgia or low-grade fever) from
actual disease is a key nursing intervention to address hesitancy
(Harrison’s Principles of Internal Medicine, 22nd ed., Chapter 3:
Vaccine Opposition and Hesitancy).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 3: Vaccine Opposition and Hesitancy.
3. A nurse is caring for a patient newly diagnosed with
hypertension who is overwhelmed by treatment options. When
applying shared decision-making, the nurse's priority action is
to:
A. Provide the patient with a detailed list of all possible
antihypertensive medications.
B. Assess the patient's values, preferences, and capacity to
understand the information.
C. Contact the physician to select the best medication for the
patient.
D. Instruct the patient to follow the standard protocol without
question for safety.
Answer: B
Rationale: Effective shared decision-making in clinical medicine
begins with understanding the patient's individual context—
their goals, concerns, and comprehension level. This aligns with
patient-centered care and ethical practice, forming the
foundation for collaborative planning (Harrison’s Principles of
Internal Medicine, 22nd ed., Chapter 4: Decision-Making in
, Clinical Medicine).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 4: Decision-Making in Clinical Medicine.
4. When discussing the concept of precision medicine with a
patient who has a strong family history of breast cancer, the
nurse should explain that it primarily involves:
A. Using population-based guidelines for all patients with the
same diagnosis.
B. Tailoring prevention and treatment strategies based on the
individual’s genetic, biomarker, and phenotypic profile.
C. Replacing all traditional therapies with novel gene therapies.
D. Focusing solely on palliative and supportive care.
Answer: B
Rationale: Precision medicine aims to customize healthcare by
using molecular and genomic information to guide decisions
about prevention, diagnosis, and treatment for individual
patients, moving beyond a "one-size-fits-all" approach
(Harrison’s Principles of Internal Medicine, 22nd ed., Chapter 5:
Precision Medicine and Clinical Care).
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.
Chapter 5: Precision Medicine and Clinical Care.
5. Which factor is most critical for a nurse to consider when
evaluating the appropriateness of a screening test for an
asymptomatic patient?
A. The cost of the test to the healthcare facility.
B. Whether the test is new and technologically advanced.
