M
Genetics and Genomics in Nursing and Health Care
M M M M M M M
by Theresa A. Beery, M. Linda Workman
M M M M M M
First Edition
M
FULL TEST BANK!!!M M
, Chapter 1: DNA Structure and Function
M M M M M
MultipleMChoice
IdentifyMtheMchoiceMthatMbestMcompletesMtheMstatementMorManswersMtheMquestion.
MMMM A. 1.M InMwhichMbodyMorMcellMareaMareMmostMgenesMinMhumansMlocated?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. PlasmaMmembrane
MMMM A. 2.M WhichMconditionMorMstatementMexemplifiesMtheMconceptMofMgenomicsMratherMthanMgenetics?
A. TheMgeneMforMinsulinMisMlocatedMonMchromosomeM11MinMallMpeople.
B. ExpressionMofManyMsingleMgeneMisMdependentMonMinheritingMtwoMalleles.
C. Sex-linkedMrecessiveMdisordersMaffectMmalesMmoreMoftenMthanMfemales.
D. OneMalleleMforMeachMgeneMisMinheritedMfromMtheMmother,MandMoneMisMinheritedMfro
mMtheMfather.
MMMM A. 3.M WhatMisMtheMpurposeMofMphosphorousMinMaMDNAMstrand?
A. LinkingMtheMnucleotidesMintoMaMstrand
B. HoldingMcomplementaryMstrandsMtogether
C. EnsuringMthatMaMpurineMisMalwaysMpairedMwithMaMpyrimidine
D. PreventingMtheMseparationMofMdouble-strandedMDNAMintoMsingle-strandedMDNA
A.
MMMM
4.MWhatMisMtheMtermMusedMtoMdefineMalternativeMformsMofMaMgeneMthatMmayMresultMinMdif
ferentMexpressionMofMtheMtraitMcodedMforMbyMthatMgene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
D. 5.MWhatMpercentageMofMbasesMinMaMstretchMofMdouble-
MMMM
strandedMDNAMthatMcontainsM30%MguanineM(G)MbasesMwouldMbeMadenineM(A)?
A.M 70%
B.M 60%
C.M 30%
D.M 20%
C.
MMMM
6.MWhatMisMtheMtermMusedMtoMdescribeMtheMorganizedMpictureMofMtheMpairedMchromoso
mesMwithinMaMcellMusedMtoMdetermineMwhetherMchromosomeMnumbers,Mstructures,MandMbanding
MpatternsMareMnormal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
D.
MMMM
7.M WhatMwouldMbeMtheMsequenceMofMDNAMthatMisMcomplementaryMtoMaMDNAMsecti
onMwithMtheMbaseMsequenceMofMGGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
, B. 8.M WhichMofMtheseMcomplementaryMbaseMpairsMformMtheMstrongestMorM“tightest”Massociation?
MMMM
A. AdenineMandMthymine
B. CytosineMandMguanine
C. GuanineMandMthymine
D. CytosineMandMadenine
A 9.M WhatMactivityMoccursMduringMMMphaseMofMtheMcellMcycle?
MMMM
A. TheMcellMundergoesMcytokinesis.
B. ActivityMstops,MandMtheMcellM“sleeps.”
C. AllMDNAMisMcompletelyMreplicated.
D. TheMcellMgreatlyMincreasesMproteinMsynthesis.
B.M 10.M WhichMchromosomeMnumberMrepresentsMtheMeuploidMstateMforMnormalMhumanMsomaticMcells?
MMMM
A. 44
B. 46
C. 47
D. 48
A.M 11.M HowMdoesMtheMproteomeMdifferMfromMtheMgenome?
MMMM
A. TheMproteomeMchangesMinMresponseMtoMintracellularMandMextracellularMsignals.
B. TheMgenomeMchangesMinMresponseMtoMintracellularMandMextracellularMsignals.
C. TheMproteomeMisMstableMinMsomaticMcellsMandMunstableMinMgermMcells,Mwhereas
MtheMgenomeMisMstableMinMbothMsomaticMcellsMandMgermMcells.
D. TheMgenomeMisMstableMinMsomaticMcellsMandMunstableMinMgermMcells,Mwhereas
theMproteomeMisMstableMinMbothMsomaticMcellsMandMgermMcells.
M
C.M 12.M WhatMisMtheMmostMoutstandingMfeatureMofMaMmatureMhaploidMcell?
MMMM
A. ItMisMusuallyMhomozygous.
B. TheMsexMchromosomesMareMmissing.
C. OnlyMoneMchromosomeMofMeachMpairMisMpresent.
D. DNAMsynthesisMoccursMafterMmitosisMinsteadMofMbefore.
D.M 13.M AtMwhatMphaseMofMtheMcellMcycleMareMchromosomesMvisibleMasMseparateMstructures?
MMMM
A. G1
B. G2
C. S
D. M
B.M 14.M WhichMstatementMaboutMtheMcellMcycleMphaseMofMG0M isMtrue?
MMMM
A. HyperplasticMgrowthMinMplaceMofMhypertrophicMgrowth
B. PerformanceMofMspecificMdifferentiatedMfunctions
C. InitiationMandMcompletionMofMnucleokinesis
D. ReplicationMofMDNA
B.M 15.M WhatMisMtheMresultMofMnormalMDNAMreplication?
MMMM
A. FormationMofMtwoMnewMdaughterMcells
B. FormationMofMtwoMidenticalMsetsMofMDNA
C. DisappearanceMofMtheMoriginalMparentMcell
D. ActivationMandMattachmentMofMspindleMfibers
, MMMM A.M 16.M WhichMstatementMregardingMchromosomeMstructureMorMfunctionMisMtrue?
A. TheMchromatidsMofManyMsingleMchromosomeMareMknownMasM“sisterMchromatids.”
B. TheMgenesMlocatedMonMtheMtelomeresMofMchromosomesMareMidenticalMtoMtheMgene
sMinMtheMcentromeres.
C. ImmediatelyMbeforeMtheMmitosisMphaseMofMcellMdivision,MtheMchromosomesMof
MallM
somaticMcellsMareMhaploid.
D. AMspecificMgeneMalleleMonMoneMchromosomeMhasMaMcomplementaryMalleleMonMtheMo
therMchromosomeMofMaMpair.
MMMM C.M 17.M WhyMdoesMaMpersonMwithMnormalMchromosomesMonlyMhaveMtwoMallelesMforManyMsingleMgeneMtrait?
A. AMminimumMofMtwoMallelesMisMrequiredMforMtheMexpressionMofMmonogenicMtraits.
B. WhenMaMdominantMalleleMisMpairedMwithMaMrecessiveMallele,MonlyMtheMdominantMalle
leMisMexpressed,MandMtheMrecessiveMalleleMisMsilent.
C. OneMalleleMforMtheMmonogenicMtraitMisMonMtheMpaternallyMderivedMchromosome,M
andMtheMotherMalleleMisMonMtheMmaternallyMderivedMchromosome.
D. ExpressionMofMmoreMthanMtwoMallelesMofManyMsingle-
geneMtraitMresultsMinMenhancedMexpressionMofMrecessiveMallelesMandMsuppressedM
expressionMofMdominantMalleles.
MMMM C 18.M UnderMwhatMnormalMconditionMareMgenotypeMandMphenotypeMalwaysMtheMsame?
A. EuploidyMofMalleles
B. AneuploidyMofMalleles
C. HomozygosityMofMalleles
D. HeterozygosityMofMalleles
MMMM D.M19.M WhatMwouldMbeMtheMexpectedMresultMofMaMdrugMthatMaffectedMaMparticularMtissueMbyMcausingM
newMDNAMtoMformMwithMcovalentMbondsMinsteadMofMhydrogenMbonds?
A. NoneMofMtheMcellsMinMtheMaffectedMtissueMwouldMbeMableMtoMleaveMG0M andMenterMth
eMcellMcycle.
B. ReplicationMofMDNAMwouldMresultMinMidenticalMDNAMstrandsMinstead
MofM
complementaryMstrands.
C. MitosisMofMcellsMinMtheMtissueMwouldMresultMinMtheMproductionMofMthreeMnewMdau
ghterMcellsMinsteadMofMjustMtwo.
D. TheMnewMcellsMthatMformedMwithinMthisMtissueMwouldMnotMbeMableMtoMcompleteMthe
MnextMroundMofMmitosisMsuccessfully.
MMMM B.M 20.M HowMdoesMtheMDNAMenzymeMtopoisomeraseMcontributeMtoMDNAMreplication?
A. UnwindsMtheMdoubleMhelixMandMseparatesMtheMdouble-strandedMDNA
B. CreatesMaM“nick”MinMtheMDNAMsupercoils,MallowingMthemMtoMstraightenMbef
oreMreplication
C. InitiatesMDNAMsynthesisMinMmultipleMsitesMdownMtheMstrand,MmakingMtheMprocessM
moreMefficient
D. ConnectsMandMlinksMtheMindividualMpiecesMofMnewlyMsynthesizedMDNAMtoMfor
mMaMsingleMstrand
MMMM A.M 21.M WhereMisMtelomericMDNAMlocated?
A. AtMtheMtipsMofMtheMpMandMqMarmsMofMchromosomes.
B. InMtheMmitochondriaMofMallMsomaticMcells
C. OnlyMinMtheMgermMcellsM(ovaMandMsperm)
D. WithinMtheMhistonesMofMtheMsolenoid