2
ASCP Chemistry Exam with accurate detailed solutions
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In absorption spectrophotometry, what relationship is absorption to concentration? -
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✔✔Absorption is directly proportional to concentration. || || || || ||
What is the equation for Beer's law? - ✔✔A= a x b x c
|| || || || || || || || || || || || ||
Where "a" equals absorptivity coefficient (a constant); "b" is the path length and "c" is
|| || || || || || || || || || || || || || ||
concentration.
A red solution transmits light at.
|| || || || || ||
And strongly absorbs light at. - ✔✔Transmits light at 600-650 nm.
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Strongly absorbs light at 400-500 nm.
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A green colored solution would show the highest transmittance between: - ✔✔500-550 nm
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Which two hormones promote glyconeogensis and promote hyperglycemia? - ✔✔Growth
|| || || || || || || || || ||
hormone. ||
And.
Cortisol.
Which hormone stimulates glycogenolysis? - ✔✔Epinephrine.
|| || || || ||
What HLA antigens are genetically associated with type 1 diabetes. - ✔✔DR3.
|| || || || || || || || || || ||
And.
DR4.
,2
What is the primary mineralocorticoid hormone that stimulates sodium reabsorption and
|| || || || || || || || || || ||
potassium secretion by the kidneys. - ✔✔Aldosterone. || || || || || ||
Does excess thyroid hormone cause hyperglycemia or hypoglycemia? - ✔✔Hyperglycemia.
|| || || || || || || || ||
What hormone opposes the action of parathyroid hormone? - ✔✔Calcitonin.
|| || || || || || || || ||
What hormone is released from the kidney due to ineffective arterial pressure and promotes
|| || || || || || || || || || || || ||
activation of angiotensinogen and aldosterone secretion? - ✔✔Renin.
|| || || || || || || ||
In type 1 diabetes, what is required to prevent ketosis? - ✔✔Insulin replacement.
|| || || || || || || || || || || ||
Excess of this hormone causes hyperglycemia by increasing glucagon and inactivation of
|| || || || || || || || || || || ||
insulin; thereby promoting both gluconeogenesis and glycogenolysis. - ✔✔Thyroid
|| || || || || || || || ||
hormone.
What is type 2 diabetes associated with? - ✔✔A defect in the receptor site for insulin.
|| || || || || || || || || || || || || || || ||
Usually occurs in patient over 40 and who are obese.
|| || || || || || || || ||
What is required of the patient's diet when getting the O.G.T.T -O'Sullivan Glucose
|| || || || || || || || || || || || ||
Tolerance Test? - ✔✔Required the patient receive at least 150g of carbohydrates per day for
|| || || || || || || || || || || || || || ||
3 days prior to test.
|| || || ||
When should the G.T.T -Glucose Tolerance Test be done? - ✔✔It should be reserved for
|| || || || || || || || || || || || || || ||
confirmation of diabetes and for difficult to diagnosis patients. || || || || || || || || ||
It is not longer recommended for screening purposes.
|| || || || || || ||
,2
What criteria is used for diagnosis of diabetes mellitus for a fasting glucose? - ✔✔greater
|| || || || || || || || || || || || || || ||
than or equal to 126 mg/dL on more than a single testing event.
|| || || || || || || || || || || ||
What criteria is used for diagnosis of diabetes mellitus for a random glucose? - ✔✔Greater
|| || || || || || || || || || || || || || ||
than or equal to 200 mg/dL on more than a single testing event.
|| || || || || || || || || || || ||
What criteria is used for diagnosis of diabetes mellitus after 2 hours following ingestion of
|| || || || || || || || || || || || || || ||
75 grams of glucose load? - ✔✔A glucose greater than or equal to 200 mg/dL on more than
|| || || || || || || || || || || || || || || || || ||
a single testing event.
|| || ||
An A1C greater than or equal to what on more than a single testing event is diagnostic of
|| || || || || || || || || || || || || || || || || ||
diabetes mellitus? - ✔✔6.5. || || ||
What is the definition of Impaired Glucose Tolerance ? - ✔✔It is serum or plasma glucose
|| || || || || || || || || || || || || || || ||
at 2 hours after a 75 g glucose load of greater than or equal to 140 mg/dL and less than 200
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mg/dL.
What is GDM? - ✔✔Gestational diabetes mellitus and it is defined as glucose intolerance
|| || || || || || || || || || || || || ||
during pregnancy. ||
When are pregnant women screened for gestational diabetes mellitus? - ✔✔Between 24 and
|| || || || || || || || || || || ||
28 weeks of gestation.
|| || || ||
What does the screening test for gestational diabetes mellitus consist of? - ✔✔An oral 50 g
|| || || || || || || || || || || || || || || ||
glucose load followed by a glucose measurement at 1 hour. || || || || || || || || || ||
A result greater than or equal to 140 mg/dL is followed by a 2 hr. or 3 hr. G.T.T to confirm
|| || || || || || || || || || || || || || || || || || || || ||
gestational diabetes. ||
If a 3 hour G.T.T is ordered, what amount of glucose load should be given? - ✔✔100 g dose.
|| || || || || || || || || || || || || || || || || ||
, 2
What are the cutoff points for the glucose tolerance test for the diagnosis of gestational
|| || || || || || || || || || || || || || ||
diabetes - ✔✔Fasting - greater to or equal to 95 mg/dL.
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1 hour- greater than or equal to 180 mg/dL.
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2 hour- greater than or equal to 155 mg/dL.
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3 hour - greater than or equal to 140 mg/dL.
|| || || || || || || || || ||
At least two cutoffs must be exceeded.
|| || || || || ||
What can cause clinical hypoglycemia? - ✔✔Insulinoma.
|| || || || || || ||
Drugs.
Alcoholism. ||
Reactive hypoglycemia. ||
What is reactive hypoglycemia characterized by? - ✔✔By delayed or excessive insulin
|| || || || || || || || || || || ||
output after eating. || || ||
Fasting insulin is normal, but post prandial levels are increased.
|| || || || || || || || ||
What is glycated hemoglobin? (G-Hgb) - ✔✔It is related to the time averaged blood glucose
|| || || || || || || || || || || || || || ||
concentration over the life span of the RBC. || || || || || || ||
How many G-Hgb fractions are there? - ✔✔3 fractions:
|| || || || || || || || ||
A1a. ||
A1b. ||
A1c
What percentage does A1c make up of the glycated hemoglobin? - ✔✔80%.
|| || || || || || || || || || ||
ASCP Chemistry Exam with accurate detailed solutions
|| || || || || ||
In absorption spectrophotometry, what relationship is absorption to concentration? -
|| || || || || || || || || ||
✔✔Absorption is directly proportional to concentration. || || || || ||
What is the equation for Beer's law? - ✔✔A= a x b x c
|| || || || || || || || || || || || ||
Where "a" equals absorptivity coefficient (a constant); "b" is the path length and "c" is
|| || || || || || || || || || || || || || ||
concentration.
A red solution transmits light at.
|| || || || || ||
And strongly absorbs light at. - ✔✔Transmits light at 600-650 nm.
|| || || || || || || || || || ||
Strongly absorbs light at 400-500 nm.
|| || || || ||
A green colored solution would show the highest transmittance between: - ✔✔500-550 nm
|| || || || || || || || || || || ||
Which two hormones promote glyconeogensis and promote hyperglycemia? - ✔✔Growth
|| || || || || || || || || ||
hormone. ||
And.
Cortisol.
Which hormone stimulates glycogenolysis? - ✔✔Epinephrine.
|| || || || ||
What HLA antigens are genetically associated with type 1 diabetes. - ✔✔DR3.
|| || || || || || || || || || ||
And.
DR4.
,2
What is the primary mineralocorticoid hormone that stimulates sodium reabsorption and
|| || || || || || || || || || ||
potassium secretion by the kidneys. - ✔✔Aldosterone. || || || || || ||
Does excess thyroid hormone cause hyperglycemia or hypoglycemia? - ✔✔Hyperglycemia.
|| || || || || || || || ||
What hormone opposes the action of parathyroid hormone? - ✔✔Calcitonin.
|| || || || || || || || ||
What hormone is released from the kidney due to ineffective arterial pressure and promotes
|| || || || || || || || || || || || ||
activation of angiotensinogen and aldosterone secretion? - ✔✔Renin.
|| || || || || || || ||
In type 1 diabetes, what is required to prevent ketosis? - ✔✔Insulin replacement.
|| || || || || || || || || || || ||
Excess of this hormone causes hyperglycemia by increasing glucagon and inactivation of
|| || || || || || || || || || || ||
insulin; thereby promoting both gluconeogenesis and glycogenolysis. - ✔✔Thyroid
|| || || || || || || || ||
hormone.
What is type 2 diabetes associated with? - ✔✔A defect in the receptor site for insulin.
|| || || || || || || || || || || || || || || ||
Usually occurs in patient over 40 and who are obese.
|| || || || || || || || ||
What is required of the patient's diet when getting the O.G.T.T -O'Sullivan Glucose
|| || || || || || || || || || || || ||
Tolerance Test? - ✔✔Required the patient receive at least 150g of carbohydrates per day for
|| || || || || || || || || || || || || || ||
3 days prior to test.
|| || || ||
When should the G.T.T -Glucose Tolerance Test be done? - ✔✔It should be reserved for
|| || || || || || || || || || || || || || ||
confirmation of diabetes and for difficult to diagnosis patients. || || || || || || || || ||
It is not longer recommended for screening purposes.
|| || || || || || ||
,2
What criteria is used for diagnosis of diabetes mellitus for a fasting glucose? - ✔✔greater
|| || || || || || || || || || || || || || ||
than or equal to 126 mg/dL on more than a single testing event.
|| || || || || || || || || || || ||
What criteria is used for diagnosis of diabetes mellitus for a random glucose? - ✔✔Greater
|| || || || || || || || || || || || || || ||
than or equal to 200 mg/dL on more than a single testing event.
|| || || || || || || || || || || ||
What criteria is used for diagnosis of diabetes mellitus after 2 hours following ingestion of
|| || || || || || || || || || || || || || ||
75 grams of glucose load? - ✔✔A glucose greater than or equal to 200 mg/dL on more than
|| || || || || || || || || || || || || || || || || ||
a single testing event.
|| || ||
An A1C greater than or equal to what on more than a single testing event is diagnostic of
|| || || || || || || || || || || || || || || || || ||
diabetes mellitus? - ✔✔6.5. || || ||
What is the definition of Impaired Glucose Tolerance ? - ✔✔It is serum or plasma glucose
|| || || || || || || || || || || || || || || ||
at 2 hours after a 75 g glucose load of greater than or equal to 140 mg/dL and less than 200
|| || || || || || || || || || || || || || || || || || || || ||
mg/dL.
What is GDM? - ✔✔Gestational diabetes mellitus and it is defined as glucose intolerance
|| || || || || || || || || || || || || ||
during pregnancy. ||
When are pregnant women screened for gestational diabetes mellitus? - ✔✔Between 24 and
|| || || || || || || || || || || ||
28 weeks of gestation.
|| || || ||
What does the screening test for gestational diabetes mellitus consist of? - ✔✔An oral 50 g
|| || || || || || || || || || || || || || || ||
glucose load followed by a glucose measurement at 1 hour. || || || || || || || || || ||
A result greater than or equal to 140 mg/dL is followed by a 2 hr. or 3 hr. G.T.T to confirm
|| || || || || || || || || || || || || || || || || || || || ||
gestational diabetes. ||
If a 3 hour G.T.T is ordered, what amount of glucose load should be given? - ✔✔100 g dose.
|| || || || || || || || || || || || || || || || || ||
, 2
What are the cutoff points for the glucose tolerance test for the diagnosis of gestational
|| || || || || || || || || || || || || || ||
diabetes - ✔✔Fasting - greater to or equal to 95 mg/dL.
|| || || || || || || || || ||
1 hour- greater than or equal to 180 mg/dL.
|| || || || || || || ||
2 hour- greater than or equal to 155 mg/dL.
|| || || || || || || || ||
3 hour - greater than or equal to 140 mg/dL.
|| || || || || || || || || ||
At least two cutoffs must be exceeded.
|| || || || || ||
What can cause clinical hypoglycemia? - ✔✔Insulinoma.
|| || || || || || ||
Drugs.
Alcoholism. ||
Reactive hypoglycemia. ||
What is reactive hypoglycemia characterized by? - ✔✔By delayed or excessive insulin
|| || || || || || || || || || || ||
output after eating. || || ||
Fasting insulin is normal, but post prandial levels are increased.
|| || || || || || || || ||
What is glycated hemoglobin? (G-Hgb) - ✔✔It is related to the time averaged blood glucose
|| || || || || || || || || || || || || || ||
concentration over the life span of the RBC. || || || || || || ||
How many G-Hgb fractions are there? - ✔✔3 fractions:
|| || || || || || || || ||
A1a. ||
A1b. ||
A1c
What percentage does A1c make up of the glycated hemoglobin? - ✔✔80%.
|| || || || || || || || || || ||
