Medical-Surgical Nursing Study Guide & Practice MCQ Test Bank (Exam Revision)

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




combined set of 20 high-yield, nursing-focused MCQs derived
from Part 1: The Profession of Medicine (Chs. 1–13) in
Harrison’s Principles of Internal Medicine, 22nd ed.


1. A nurse is reinforcing lifestyle counseling during a routine
visit. Which intervention has the greatest population-level
impact on premature mortality?
A. Daily multivitamin use
B. Tobacco cessation
C. Increased protein intake
D. Routine full-body imaging
Answer: B
Rationale: Tobacco use remains one of the leading preventable
causes of death worldwide, contributing to cardiovascular

,disease, cancer, and chronic lung disease. Smoking cessation is
among the most effective health-promoting interventions.
Citation: Harrison’s Principles of Internal Medicine, 22e, Ch. 2 –
Promoting Good Health


2. Which nursing approach best addresses vaccine hesitancy in
a parent who is unsure about immunizing their child?
A. Provide printed statistics and end the discussion
B. Dismiss concerns to prevent misinformation
C. Use empathetic listening and motivational interviewing
D. Inform the parent vaccines are legally required
Answer: C
Rationale: Vaccine hesitancy is best managed through
respectful dialogue, acknowledgment of concerns, and
motivational interviewing to build trust and improve vaccine
acceptance.
Citation: Harrison’s Principles of Internal Medicine, 22e, Ch. 3 –
Vaccine Opposition and Hesitancy


3. A nurse is helping a patient choose between two treatment
options with similar outcomes but different side effects. This
reflects which model of clinical decision-making?
A. Paternalistic model
B. Shared decision-making

, C. Defensive medicine
D. Algorithm-driven care
Answer: B
Rationale: Shared decision-making integrates clinical evidence
with patient values and preferences, particularly when
multiple reasonable options exist.
Citation: Harrison’s Principles of Internal Medicine, 22e, Ch. 4 –
Decision-Making in Clinical Medicine


4. Which scenario best demonstrates precision medicine?
A. Prescribing the same antihypertensive for all patients
B. Adjusting therapy based on genetic tumor markers
C. Using age-based screening guidelines
D. Recommending exercise for all adults
Answer: B
Rationale: Precision medicine uses molecular, genetic, and
biomarker information to tailor diagnosis and treatment to
the individual patient.
Citation: Harrison’s Principles of Internal Medicine, 22e, Ch. 5 –
Precision Medicine and Clinical Care


5. A nurse schedules a colonoscopy for an asymptomatic 52-
year-old patient. This is an example of: